Product Description: Recombinant DNA techniques have revolutionized the isolation and production of antibodies. This volume describes methods and technologies which will allow the researchers to isolate a new antibody, analyse its properties, format the correct antibody or fragment, and produce sufficient quantities for experimental use...read more

Product Description: Cell biologists have recently come to understand that asymmetry of division is an important regulatory phenomenon in the fate of a cell. In adult organisms asymmetric divisions regulate the stem cell reservoir and are a source of the drift that contributes to aging...read more

Product Description: Discover the power of recovery ministry for your church. Churchgoers who experience painful family issues, addictions, abuse, loss, mental illnesses, and other secret sorrows begin to believe they live beyond the grip of God’s redemptive hand...read more

Product Description: Homologous recombination involves the precise exchange of similar or identical nucleic acid sequences between two DNA molecules. This process directs the repair of many DNA lesions in somatic cells and generates genetic variation in sperm and egg cells during meiosis...read more

Product Description: The processes of DNA recombination and repair are vital to cell integrity -- an error can lead to a disease such as cancer. These processes are therefore expanding areas of research and are now being taught in many undergraduate and postgraduate courses...read more (view table of contents, read Amazon.com's description)

This book provides an in-depth analysis of the mechanisms and biological consequences of genome rearrangements in bacteria. Genome rearrangements are a result of the actions of discrete genetic elements such as conjugative transposons, plasmids, phage, and non-conjugative transposons. Bacteria also contain systems to mediate genetic rearrangements such as the general recombination pathway and specialized endogenous recombination mechanisms. The biological effects of these rearrangements are far-reaching and impact on bacterial virulence, antibiotic resistance and the ability of bacteria to avoid the attentions of the host immune system (e.g. antigenic variation). These rearrangements also provide the raw material on which natural selection can act. Each chapter examines the mechanisms involved in genome rearrangements and the direct biological consequences of these events. This book is written by leading research workers and is an invaluable resource for graduate students and researchers in this field.

Product Description: Describing the scientific and commercial applications of microbial recombinant DNA technology, this outstanding, single-source reference offers state-of-the-art reviews of gene expression in the most important classes of recombinant microorganisms-providing numerous examples of the expression of homologous genes or heterologous gene products...read more

Product Description: In recent years, the DNA sequence rearrangements, widespread in both prokaryotes and eurkaryotes, have been the subject of intense research effort. "Gene Rearrangement" describes the latest developments in a number of areas of current interest, including genomic rearrangements in prokaryotes, the molecular basis of antigenic variation in African trypanosomes, and DNA amplification in eukaryotes...read more

Product Description: Gene targeting offers new approaches to basic research and holds out the promise of eventual correction of genetic diseases. With simple, direct language and extensive illustrations, this advanced textbook offers a comprehensive review of homologous recombination and gene targeting techniques - the basic principles, methods, applicatiuons, and social implications...read more

Product Description: This title presents Nobel Laureate Arthur Kornberg's formal San Diego State University Distinguished Graduate Research Lecture. It is followed by excerpts from a colloquium discussion and by a short bibliography. Originally published in 1988.

Product Description: This book is concerned with the genetic consequences of nu­ cleotide pool imbalance. There are a number of ways in which this state can be achieved and the majority of papers in this volume de­ scribe the effects of nucleotide pool imbalance on DNA replication and repair, and the induction of gene mutations in various organisms...read more

Product Description: The twin aims of this new introductory textbook are; firstly to discuss the concepts and experimental strategies of research into genetic recombination in simple terms, and secondly to demonstrate how the different types of recombination - homologous, site-specific, transpositional and illegitimate - are related...read more

Product Description: Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Genetic recombination is a process by which a molecule of nucleic acid (usually DNA; but can also be RNA) is broken and then joined to a different DNA molecule...read more

Product Description: Genetic recombination, in the broadest sense, can be defined as any process in which DNA sequences interact and undergo a transfer of information, producing new “recombinant” sequences that contain information from each of the original molecules...read more

Product Description: A Safety Considerations Genomic sequencing involves a number of hazardous steps, such as high current, high voltage, radioactive and highly toxic chemicals. It is, therefore, absolutelyessen- tial that the instructions of equipment manufacturers be followed and that particular attention is paid to the local and federal safety regulations...read more

Product Description: As researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In this book, scientists from around the world, who are leaders in this field, contribute their vast experience and expertise to produce a comprehensive and fascinating text for researchers and clinicians alike...read more