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Genetic Recombination: Reviews and Protocols
By Alan S. Waldman (editor)
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Bibliographic Detail
Publisher Humana Pr Inc
Publication date November 10, 2010
Pages 272
Binding Paperback
Edition Reprint
Book category Adult Non-Fiction
ISBN-13 9781617374425
ISBN-10 1617374423
Original list price $139.00
Other format details sci/tech
Summaries and Reviews
Amazon.com description: Product Description: Genetic recombination, in the broadest sense, can be defined as any process in which DNA sequences interact and undergo a transfer of information, producing new “recombinant” sequences that contain information from each of the original molecules. All organisms have the ability to carry out recombination, and this striking universality speaks to the essential role recombination plays in a variety of biological processes fundamentally important to the maintenance of life. Such processes include DNA repair, regulation of gene expression, disease etiology, meiotic chromosome segregation, and evolution. One important aspect of recombination is that it typically occurs only between sequences that display a high degree of sequence identity. The stringent requirement for homology helps to ensure that, under normal circumstances, a cell is protected from deleterious rearrangements since a swap of genetic information between two nearly identical sequences is not expected to dramatically alter a genome. Recombination between dissimilar sequences, which does happen on occasion, may have such harmful consequences as chromosomal translocations, deletions, or inversions. For many organisms, it is also important that recombination rates are not too high lest the genome become destabilized. Curiously, certain organisms, such as the trypanosome parasite, actually use a high rate of recombination at a particular locus in order to switch antigen expression continually and evade the host immune system effectively.

Editions
Hardcover
Book cover for 9781588292360
 
from Humana Pr Inc (April 1, 2004)
9781588292360 | details & prices | 260 pages | 6.00 × 9.00 × 0.75 in. | 1.25 lbs | List price $139.00
About: Genetic recombination, in the broadest sense, can be defined as any process in which DNA sequences interact and undergo a transfer of information, producing new “recombinant” sequences that contain information from each of the original molecules.
Paperback
Book cover for 9781617374425
 
The price comparison is for this edition
Reprint edition from Humana Pr Inc (November 10, 2010)
9781617374425 | details & prices | 272 pages | List price $139.00
About: Genetic recombination, in the broadest sense, can be defined as any process in which DNA sequences interact and undergo a transfer of information, producing new “recombinant” sequences that contain information from each of the original molecules.

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