Product Description: For many years I performed tissue culture in large scientific insti- tions that had a great deal of infrastructure. When I set up a tissue l- oratory outside such an infrastructure, however, I found there was a shortage of easily accessible information about the basic needs, reagents, and techniques for establishing such a facility...read more

Product Description: The ability to introduce macromolecules into animal cells, includ­ ing DNA, RNA, proteins, and other bioactive compounds has facili­ tated a broad range of biological studies, from biochemistry and biophysics to molecular biology, cell biology, and whole animal stud­ ies...read more

Product Description: This book introduces fundamental principles and practical application of techniques used in the scalable production of biopharmaceuticals with animal cell cultures. A broad spectrum of subjects relevant to biologics production and manufacturing are reviewed, including the generation of robust cell lines, a survey of functional genomics for a better understanding of cell lines and processes, as well as advances in regulatory compliant upstream and downstream development...read more

Product Description: Animal cell technology is a discipline of growing importance, which aims not merely at understanding structure, function and behaviour of differentiated animal cells, but especially at the development of their abilities useful for clinical application...read more

The second edition of this book constitutes a comprehensive manual of new techniques for setting up mammalian cell lines for production of biopharmaceuticals, and for optimizing critical parameters for cell culture considering the whole cascade from lab to final production. The chapters are written by world-renowned experts and the volume’s five parts reflect the processes required for different stages of production. This book is a compendium of techniques for scientists in both industrial and research laboratories that use mammalian cells for biotechnology purposes.

This body of work represents the first volume of a book series covering the field of tissue engineering. Tissue engineering, which refers to a category of therapeutic or diagnostic products and processes which are based upon a combination of living cells and biomaterials, was defined as a field only a few years ago (1988). Tissue engineering is an inherently interdisciplinary field, combining bioengineering, life sciences and clinical sciences. The definition of this area of work as the field of tissue engineering brought together scientists from multiple backgrounds who already were working toward the achievement of similar goals. Why a book series exclusively devoted to tissue engineering? The field of tissue engineering is heterogeneous. The cells involved in tissue engineering can be autologous, allogeneic or xenogeneic. The biomaterials utilized can be either naturally occurring, synthetic or a combination of both. The appli­ cation of the technology can be either for acute or permanent purposes. An attempt to cover the field of tissue engineering in a single volume, with the degree of detail necessary for individuals with different scientific back­ grounds and disciplines, would be a difficult task to accomplish, particularly when this field is just emerging and changing rapidly. Therefore, addressing different technologies within the field of tissue engineering, in a comprehen­ sive manner, is the main mission of this series of volumes. A stellar group of scientists has been brought together to form the editorial board of the series.

Product Description: In the past two decades, the importance of animal cell technology has increased enormously. First, useful proteins can be produced by cultured animal cells, in which the desired product can be modified and organized so as to retain its biological function...read more

Product Description: Cell Biology and Biotechnology: Novel Approaches to Increased Cellular Productivity contains the proceedings of the symposium by the same name held in Cambridge, Massachusetts, January 30 - February 2, 1992. State-of-the-art research is presented on: the IGF-1 Receptor and Gene Expression During the Cell Cycle; Attachment Control of Fibroplast Proliferation; Cell Biology and Serum-Free Mouse Embryo Cells; Immunoglobulin Production Stimulating Factors; Erythropoietin Control of Programmed Death in Erythroid Progenitors; Prohormone Processing Enzymes and Protein Production; Control of Translation Initiation by Phosphorylation; Protein Retention in the Endoplasmic Reticulum Mediated by GPR78; Molecular Approaches Towards Manipulating the Expression of the Glucose Related Proteins in Mammalian Cells; Protein Folding in the Endoplasmic Reticulum; Sorting of Membrane Proteins in the Endocytic and Exocytic Pathways; CIS-Acting Elements Which Regulate Immunoglobulin Gene Transcription...read more

Product Description: The efficiency of delivering DNA into mammalian cells has increased t- mendously since DEAE dextran was first shown to be capable of enhancing transfer of RNA into mammalian cells in culture. Not only have other chemical methods been developed and refined, but also very efficient physical and viral delivery methods have been established...read more

Product Description: Highly experienced researchers describe in step-by-step detail methods that have proven most useful in delivering genes to mammalian cells. Volume 1: Nonviral Gene Transfer Techniques focuses on gene delivery by a variety of chemical and physical methods, including ultrasound, biolistics, peptides, PNA clamps, liposomes, microinjection, electroporation, particle bombardment, dendrimers, and hydrodynamics...read more

Product Description: There is an urgent need to develop new approaches to treat conditions as- ciated with the aging global population. The surgeon’s approach to many of these problems could be described as having evolved through three stages: Removal: Traditionally, diseased or badly damaged tissues and structures might simply be removed...read more

Product Description: Animal cell technology is a growing discipline of cell biology which aims not only to understand the structure, function and behavior of differentiated animal cells, but also to ascertain their ability to be used for industrial and medical purposes...read more

Product Description: The advancement of science is ever more contingent upon the interaction of experts vast amount of scientific information being gathered every day that exceeds the ability of any one scientist to acquire. As an illustration of the frantic pace of scientific disc- more acute in the case of scientific fields at the interface of different and seemingly distant areas of study...read more

Product Description: Animal Cell Technology is a growing discipline of cell biology which aims not only to understand structures, functions and behaviours of differentiated animal cells, but also to ascertain their abilities to be used in industrial and medical purposes...read more

Product Description: Animal cell technology is a growing discipline of cell biology which aims not only to understand structures, functions and behaviors of differentiated animal cells, but also to ascertain their abilities to be used for industrial and medical purposes...read more

This book focuses on practical applications for using adult and embryonic stem cells in the pharmaceutical development process. It emphasizes new technologies to help overcome the bottlenecks in developing stem cells as therapeutic agents. A key reference for professionals working in stem cell science, it presents the general principles and methodologies in stem cell research and covers topics such as derivitization and characterization of stem cells, stem cell culture and maintenance, stem cell engineering, applications of high-throughput screening, and stem cell genetic modification with their use for drug delivery.

Product Description: Animal Cell Technology: from Biopharmaceuticals to Gene Therapy provides a comprehensive insight into biological and engineering concepts related to mammalian and insect cell technology, as well as an overview of the applications of animal cell technology...read more

Product Description: This book provides a comprehensive volume that integrates a wide spectrum of methods required to implement current and future progress in tissue engineering. Leading experts in various disciplines provide examples of recent advances in tissue engineering-related methodologies...read more

Product Description: The 19th ESACT meeting was to highlight the novel capabilities of the industry to move the products towards the clinic. It was attended by a wide range of workers in the industry and for many it was their first ESACT meeting. The proceedings here include the short papers adding the knowledge of the previous meetings and provide a reference for the researcher entering, or continuing in the field of Animal Cell Technology...read more

Product Description: Tocci and Widmer use a block diagram approach to basic logic operations, enabling readers to have a firm understanding of logic principles before they study the electrical characteristics of the logic ICs. KEY TOPICS For each new device or circuit, the authors describe the principle of the operation, give thorough examples, and then show its actual application...read more (view table of contents, read Amazon.com's description)

Product Description: Cell immobilisation biotechnology is a multidisciplinary area, shown to have an important impact on many scientific subdisciplines – including biomedicine, pharmacology, cosmetology, food and agricultural sciences, beverage production, industrial waste treatment, analytical applications, biologics production...read more