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With the rise of genomics, the life sciences have entered a new era. Maps of genomes have become the icons for a comprehensive knowledge of the organism on a previously unattained level of complexity, and the organisation of genetic knowledge in maps has been a major driving force in the establishment of the discipline. This book provides a comprehensive history of molecular genetics and genomics.The first section of the book shows how the genetic cartography of classical genetics was linked to the molecular analysis of gene structure through the introduction of new model organisms such as bacteria and through the invention of new experimental tools such as gene transfer. The second section addresses the moral and political economy of human genome sequencing in all its technical, epistemic, social and economic complexity.With detailed analyses of the scientific practices of mapping and its illustration of the diversity of mapping practices this book is a significant contribution to the history of genetics. A companion volume from the same editors - Classical Genetic Research and Its Legacy: The Mapping Cultures of Twentieth Century Genetics - covers the history of mapping procedures as they were developed in classical genetics.

Product Description: Until the middle of the eighteenth century, the biological makeup of an organism was ascribed to an individual instance of "generation" -- involving conception, pregnancy, embryonic development, parturition, lactation, and even astral influences and maternal mood -- rather than the biological transmission of traits and characteristics...read more

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Product Description: In this powerful work of conceptual and analytical originality, the author argues for the primacy of the material arrangements of the laboratory in the dynamics of modern molecular biology. In a post-Kuhnian move away from the hegemony of theory, he develops a new epistemology of experimentation in which research is treated as a process for producing epistemic things...read more (view table of contents, read Amazon.com's description)