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Robert Crichton has written 9 work(s)
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Iron is of fundamental importance to the growth, development and well-being of almost all living organisms. Multiple biological systems have evolved for the uptake, utilisation, storage, and homeostasis of iron in microbes, plants and mammals. Both iron deficiency and iron overload are found extensively in humans; the intimate links between iron and oxidative stress are associated with a wide range of pathologies. Iron has a well established role in infections by a range of microorganisms and parasites. Other metals such as copper and zinc are also closely linked with iron metabolism. Iron overloads and deficiencies are important factors in the health of humans and are therefore a key target in drug development. Iron Metabolism: From Molecular Mechanisms to Clinical Consequences, 3rd Edition presents a comprehensive overview of this important field.Topics covered include: Solution chemistry of iron in biological media The importance of iron for biological systems Microbial iron transport and metabolism Iron uptake by plants and fungi Cellular iron uptake and export in mammals Intracellular iron storage and biomineralization Intracellular iron metabolism and cellular iron homeostasis Iron absorption in mammals, with particular reference to man, and regulation of systemic iron balance Pathophysiology of iron deficiency and iron overload in man Iron and oxidative stress Brain iron homeostasis and its perturbation in various neurodegenerative diseases Interactions between iron and other metals Written in a lively style by one of the leaders in the field and presented in full colour, this third, expanded edition of Iron Metabolism has been fully updated with the latest discoveries. Major additions include recent information on mitochondrial iron metabolism and the role of frataxin; transcriptional control of iron homeostasis; orally active iron chelators; the roles of hepcidin and erythropoietin; the increasing number of types of iron overload; and the importance of iron in Alzheimerâs disease. Iron Metabolism is essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and the medical sciences. It will also find space on the bookshelves of bioinorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, and pharmacologists in the pharmaceutical industry interested in developing novel iron-binding drugs.
Hardcover:
9781118925614 | 4th edition (John Wiley & Sons Inc, May 31, 2016), cover price $195.00
9780470010280 | 3 edition (John Wiley & Sons Inc, June 15, 2009), cover price $234.00 | About this edition: Iron is of fundamental importance to the growth, development and well-being of almost all living organisms.
Miscellaneous:
9780470010297 | 3 edition (John Wiley & Sons Inc, March 12, 2009), cover price $370.00
Miscellaneous:
9780470010303 | 3 onl edition (John Wiley & Sons Inc, June 15, 2009), cover price $180.00
Product Description: Dementia and neurodegenerative diseases such as Parkinsonâs and Alzheimerâs are becoming an increasingly important cause of medical and social concern due to the growth in the ageing population. Mechanisms and Metal Involvement in Neurodegenerative Diseases delivers in one volume a streamlined source of information on each of the main neurodegenerative diseases including mild cognitive impairment, Parkinson's, Alzheimer's, Freiderich's ataxia, prion disease, multiple sclerosis and alcoholic brain damage...read more
Hardcover:
9781849735889 | 1 edition (Royal Society of Chemistry, July 24, 2013), cover price $240.00 | About this edition: Dementia and neurodegenerative diseases such as Parkinsonâs and Alzheimerâs are becoming an increasingly important cause of medical and social concern due to the growth in the ageing population.
Product Description: Remote from the rest of war-torn Italy, the little town of Santa Vittoria has but one thing to boast of: its fabulous wine cellars. For this cause, the citizens, led by their wine-loving mayor Bombolini, scheme and plot to prevent the Germans from locating and looting the town's only treasure...read more
Paperback:
9780192815927, titled "Little Dorrit" | Reprint edition (Oxford Univ Pr, August 1, 1982), cover price $7.95 | also contains Little Dorrit | About this edition: The daughter of an imprisoned debtor suffers injustices of nineteenth-century English society
CD/Spoken Word:
9781441703378 | Mp3 una edition (Blackstone Audio Inc, July 20, 2010), cover price $29.95 | About this edition: Remote from the rest of war-torn Italy, the little town of Santa Vittoria has but one thing to boast of: its fabulous wine cellars.
9781441703347 | Unabridged edition (Blackstone Audio Inc, July 20, 2010), cover price $109.00 | About this edition: Remote from the rest of war-torn Italy, the little town of Santa Vittoria has but one thing to boast of: its fabulous wine cellars.
Hardcover:
9781568491493 | Buccaneer Books, October 30, 2007, cover price $21.95
Paperback:
9780881842678 | Carroll & Graf Pub, November 1, 1986, cover price $3.95 | About this edition: The clownish Bombolini becomes a man of significance when he devises a plan to prevent the Germans from taking Santa Vittoria's liquor supply
Miscellaneous:
9780470852033 | 2 edition (John Wiley & Sons Inc, June 9, 2003), cover price $475.00
Product Description: Remote from the rest of war-torn Italy, the little town of Santa Vittoria has but one thing to boast of: its fabulous wine cellars. For this cause, the citizens, led by their wine-loving mayor Bombolini, scheme and plot to prevent the Germans from locating and looting the town's only treasure...read more
Cassette/Spoken Word:
9780786112036 | Unabridged edition (Blackstone Audio Inc, December 1, 1997), cover price $69.95 | About this edition: Remote from the rest of war-torn Italy, the little town of Santa Vittoria has but one thing to boast of: its fabulous wine cellars.
Paperback:
9780881843187 | Carroll & Graf Pub, June 1, 1987, cover price $4.95 | About this edition: A Scottish girl living in the coal-mining town of Pitmungo, sets out on her sixteenth birthday to find a husband who will help her achieve social success
Hardcover:
9780394465821 | Alfred a Knopf Inc, November 1, 1972, cover price $10.00 | About this edition: A Scottish girl living in the coal-mining town of Pitmungo, sets out on her sixteenth birthday to find a husband who will help her achieve social success
Miscellaneous:
9780080556222 | Elsevier Science Pub Ltd, June 30, 1905, cover price $94.95
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