search for books and compare prices
By
Jean-Claude Tardif (editor) and
Martial G. Bourassa (editor)
Price
Store
Arrives
Preparing
Shipping
Jump quickly to results on these stores:
The price is the lowest for any condition, which may be new or used; other conditions may also be available.
Bibliographic Detail
Publisher
Springer Verlag
Publication date
October 14, 2012
Pages
258
Binding
Paperback
Edition
Reprint
Book category
Adult Non-Fiction
ISBN-13
9789401058810
ISBN-10
9401058814
Dimensions
0.75 by 6.50 by 9.25 in.
Original list price
$129.00
Summaries and Reviews
Amazon.com description: Product Description: Generation of oxidants or reactive oxygen species is a natural process of human biology. Mitochondrial respiration, phagocytic activity and cyclooxygenase activation are all essential processes of life, which also generate oxidative species. In humans, chronic oxidative stress often coupled with deficiency of antioxidant defenses is associated with the aging process and can lead to the development of disorders such as cancer and arterial disease. Major cardiovascular conditions in which oxidative damage has been strongly implicated include atherosclerosis, myocardial ischemia and reperfusion, coronary restenosis and congestive heart failure. Compelling evidence points to oxidative stress as an important trigger in the complex chain of events leading to atherosclerosis. The expression of chemotactic factors and adhesion molecules is modified by oxidative stress. Exposure to superoxide ions activates the NF-kappa B regulatory complex and triggers the transcription of several atherosclerosis related genes. These events lead to the accumulation of macrophages in the arterial wall. Macrophages avidly incorporate oxidized low-density lipoproteins (LDL) to form foam cells. The activity of matrix metalloproteinases is also regulated by oxidative stress. This activity appears to be closely coupled with smooth muscle cell activation and migration. Matrix metalloproteinases have also been implicated in the pathophysiology of plaque rupture. Antioxidant supplementation including vitamin E decreases susceptibility ofLDL to oxidation and retards the progression of atherosclerosis in animal models.
Editions
Hardcover
2 edition from Springer Verlag (December 1, 2005)
9780387295527 | details & prices | 494 pages | 7.25 × 10.00 × 1.00 in. | 2.70 lbs | List price $249.00
About: Chronic oxidative stress is associated with the aging process and often leads to the development of disorders such as cancer and arterial disease.
About: Chronic oxidative stress is associated with the aging process and often leads to the development of disorders such as cancer and arterial disease.
Paperback
2 edition from Springer Verlag (December 5, 2014)
9781489995926 | details & prices | List price $249.00
About: Chronic oxidative stress is associated with the aging process and often leads to the development of disorders such as cancer and arterial disease.
About: Chronic oxidative stress is associated with the aging process and often leads to the development of disorders such as cancer and arterial disease.
The price comparison is for this edition
Reprint edition from Springer Verlag (October 14, 2012)
9789401058810 | details & prices | 258 pages | 6.50 × 9.25 × 0.75 in. | 0.95 lbs | List price $129.00
About: Generation of oxidants or reactive oxygen species is a natural process of human biology.
About: Generation of oxidants or reactive oxygen species is a natural process of human biology.
Pricing is shown for items sent to or within the U.S., excluding shipping and tax. Please consult the store to determine exact fees. No warranties are made express or implied about the accuracy, timeliness, merit, or value of the information provided. Information subject to change without notice. isbn.nu is not a bookseller, just an information source.