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By
John K. Buolamwini (editor) and
Alex A. Adjei (editor)
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Bibliographic Detail
Publisher
Humana Pr Inc
Publication date
August 16, 2013
Binding
Paperback
Edition
Reprint
Book category
Adult Non-Fiction
ISBN-13
9781489938398
ISBN-10
1489938397
Dimensions
0 by 5 by 9 in.
Original list price
$169.00
Other format details
medical
Summaries and Reviews
Amazon.com description: Product Description: We are in an exciting era in the war against cancer, with real prospects for novel anticancer drugs that are cancer cell-specific without the toxicities that have been the hallmark of conventional cytotoxic cancer chemotherapy. Advances in cancer cell biology fueled by the molecular biology revolution have resulted in the uncovering of many novel potential molecular targets for cancer therapy. New anticancer drug discovery and development is now largely focused on exploiting these new molecular targets, which encompass oncogenes, tumor s- pressor genes, and their gene products, as well as targets involved in tumor angiogenesis, metastasis, survival, and longevity mechanisms. Exploitation of some of these targets has already yielded fruits and introduced new paradigms of molecularly targeted cancer therapy into the clinic, namely, protein kinase in- bition by antibodies or small molecules, exemplified by Herceptin® (trastuzumab), a humanized antibody targeted against the HER-2 growth factor receptor tyrosine kinase for the treatment of metastatic breast cancer; and Gleevec, a small molecule bcr-abl kinase inhibitor for the treatment of chronic myel- enous leukemia.
Editions
Hardcover
Ill edition from Humana Pr Inc (April 1, 2003)
9780896039636 | details & prices | 500 pages | 6.00 × 9.25 × 1.00 in. | 1.65 lbs | List price $199.00
Paperback
The price comparison is for this edition
With John K. Buolamwini (other contributor) |
Reprint edition from Humana Pr Inc (August 16, 2013)
9781489938398 | details & prices | List price $169.00
About: We are in an exciting era in the war against cancer, with real prospects for novel anticancer drugs that are cancer cell-specific without the toxicities that have been the hallmark of conventional cytotoxic cancer chemotherapy.
About: We are in an exciting era in the war against cancer, with real prospects for novel anticancer drugs that are cancer cell-specific without the toxicities that have been the hallmark of conventional cytotoxic cancer chemotherapy.
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