One is a fifteen—year—old boy with an uncanny ability to recite every bone in the skeletal system whenever he gets anxious — and that happens a lot. The meaning of "appropriate behaviour" mystifies him: he doesn't understand most people and they certainly don't understand him.

The other is a graduating senior with the world at her feet. Joining the Best Buddies club at her school and pairing up with a boy with Aspergers/autism is the perfect addition to her med school applications. Plus, the president of the club is a rather attractive, if mysterious, added bonus.

Told in the alternating voices of Harrison and Anna, Fragile Bones is the story of two teens whose lives intertwine in unexpected ways.

Each One—to—One novel tells the story of a different pair of teens participating in the Best Buddies program at Sir Winston Churchill Secondary School. Follow the lives of this group of friends who come together with different expectations and problems, seeing the world from their own unique perspectives and facing it head on together.