Amazon.com description: Product Description: This textbook contains an account of self/non self discrimination in other invertebrate and vertebrate organisms. Klein demonstrates how the intricate molecular and cellular mechanisms of defence are fashioned by evolution as answers to a variety of biological problems of survival. He goes on to describe our understanding of lymphoid organs, T and B cells, immunoglobulins, lymphokines, histocompatibility, tolerance and the concepts and experiments that define modern immunology. Up-to-date and aiming to do justice to the new molecular understanding of the subject this book redefines the contours of a discipline that increasingly occupies centre stage in modern life science. It emphasizes current trends in immunological research and describes the organization of the immune system, the components of the immune response and the immune system and disease.