When there is uncertainty about the gender identity or social gender role of an individual, determining exactly who the opposite sex is can be a complicated question for both the transgender person and for those who seek to relate to her. Written in both an enlightened and a reader friendly style interspersed with vignettes, When the Opposite Sex Isn’t offers a combination of insights and common sense understanding of the diversity of the human condition together with concepts of gender and sexuality that expand the horizons of any mental health professional, regardless of the clinical focus of his or her work. Samons challenges concepts once taken for granted, thus providing stimulus for creative thinking which many lay readers will also find interesting and entertaining, whether or not they are (thus far) acquainted with a transgender person.