Preface

Contributors

Construction of Microsatellite-Based, High-Resolution Genetic Maps in the Mouse

Paul A. Lyons

Genetic Analysis of Complex Traits

Stephen P. Bryant

Mathias N. Chiano

Sequence-Based Detection of Single Nucleotide Polymorphisms

Deborah A. Nickerson

Natali Kolker

Scott L. Taylor

Mark J. Rieder

Genomic Mismatch Scanning for the Mapping of Genetic Traits

Farideh Mirzayans

Michael A. Walter

Detection of Chromosomal Abnormalities by Comparative Genomic Hybridization

Mario A. J. A. Hermsen

Marjan M. Weiss

Gerrit A. Meijer

Jan P. A. Baak

Construction of a Bacterial Artificial Chromosome Library

Sangdun Choi

Ung-Jin Kim

Contiguation of Bacterial Clones

Sean J. Humphray

Susan J. Knaggs

Ioannis Ragoussis

Mapping of Genomic Clones by Fluorescence In Situ Hybridization

Margaret A. Leversha

Map Integration: From a Genetic Map to a Physical Gene Map and Ultimately to the Sequence Map

Panagiotis Deloukas

Construction of Full-Length-Enriched cDNA Libraries: The Oligo-Capping Method

Yutaka Suzuki

Sumio Sugano

Construction of Transcript Maps by Somatic Cell/Radiation Hybrid Mapping: The Human Gene Map

Panagiotis Deloukas

Preparation and Screening of High-Density cDNA Arrays with Genomic Clones

Gunther Zehetner

Maria Pack

Katja Schafer

Direct Selection of cDNAs by Genomic Clones

Daniela Toniolo

Exon Trapping: Application of a Large-Insert Multiple-Exon-Trapping System

Martin C. Wapenaar

Johan T. Den Dunnen

Sequencing Bacterial Artificial Chromosomes

David E. Harris

Lee Murphy

Finding Genes in Genomic Nucleotide Sequences by Using Bioinformatics

Yvonne J. K. Edwards

Simon M. Brocklehurst

Gene Identification Using the Pufferfish, Fugu rubripes, by Sequence Scanning

Greg Elgar

Isolation of Differentially Expressed Genes Through Subtractive Suppression Hybridization

Oliver Dorian von Stein

Isolation of Differentially Expressed Genes by Representational Difference Analysis

Christine Wallrapp

Thomas M. Gress

Expression Profiling and the Isolation of Differentially Expressed Genes by Indexing-Based Differential Display

Michael P. Starkey

Expression Profiling by Systematic High-Throughput In Situ Hybridization to Whole-Mount Embryos

Nicolas Pollet

Christof Niehrs

Expression Monitoring Using cDNA Microarrays: A General Protocol

Xing Jian Lou

Mark Schena

Frank T. Horrigan

Richard M. Lawn

Ronald W. Davis

Prediction of Protein Structure and Function by Using Bioinformatics

Yvonne J. K. Edwards

Amanda Cottage

Identification of Novel Genes by Gene Trap Mutagenesis

Anne K. Voss

Tim Thomas

Determination of Gene Function by Homologous Recombination Using Embryonic Stem Cells and Knockout Mice

Ahmed Mansouri

Genomic Analysis Utilizing the Yeast Two-Hybrid System

Ilya G. Serebriiskii

Garabet G. Toby

Russell L. Flnley, Jr.

Erica A. Golemis

Methods for Adeno-Associated Virus-Mediated Gene Transfer into Muscle

Terry J. Amiss

Richard Jude Samulski

Retroviral-Mediated Gene Transduction

Donald S. Anson

Gene Therapy Approaches to Sensitization of Human Prostate Carcinoma to Cisplatin by Adenoviral Expression of p53 and by Antisense Jun Kinase Oligonucleotide Methods

Ruth Gjerset

Ali Haghighi

Svetlana Lebedeva

Dan Mercola

Ribozyme Gene Therapy

Leonidas A. Phylactou

Index