search for books and compare prices
Tables of Contents for Medical Management of Pulmonary Diseases
Chapter/Section Title
Page #
Page Count
Preface
v
Contributors
xxiii
I. The Anatomy and Physiology of the Respiratory Tract
Anatomy of the Respiratory System
1
14
Theodore W. Marcy
Gerald S. Davis
Overview
1
1
Function of the Respiratory System
1
2
Structure-Function Relationships
3
10
Summary
13
2
Suggested Reading
13
2
Muscles, Nerves, and Central Control of Respiration
15
16
James C. Leiter
Respiratory Muscles and Nerves
15
4
Central Control of Respiration
19
6
Integrated Control
25
6
Suggested Reading
29
2
Principles of Air Movement Into and Out of the Lung
31
20
David A. Kaminsky
Introduction
31
1
Forces Involved in Air Movement
32
4
Air Movement Into the Lung
36
7
Air Movement Out of the Lung
43
2
Work of Breathing
45
2
Summary
47
1
Appendix
48
3
Suggested Reading
49
2
Principles of Blood Flow, Gas Exchange, and Oxygen Delivery
51
14
Jason Kelley
Introduction
51
1
Blood Flow
51
2
Gas Exchange
53
7
Oxygen Transport and Delivery
60
3
Carbon Dioxide Clearance
63
2
Suggested Reading
64
1
Host Defense Mechanisms of the Lung
65
14
Herbert Y. Reynolds
Introduction
65
3
Overview
68
3
Alveolar Space--Air Exchange Surface
71
2
Recognition and Characterization of Defects in Host Defense
73
6
Suggested Reading
78
1
II. Symptoms and Signs of Respiratory Disease
The Respiratory System: History
79
14
Gerald S. Davis
Theodore W. Marcy
Symptoms of Respiratory Disease
79
8
Past Medical History, Family History, and Smoking
87
1
Occupational and Environmental Exposure History
88
2
Medication Use History
90
2
Conclusions
92
1
Suggested Reading
92
1
Physical Examination of the Respiratory System and Thorax
93
18
Gerald S. Davis
Theodore W. Marcy
Inspection
93
3
Digital Clubbing
96
2
Palpation
98
4
Percussion
102
1
Auscultation
103
3
Cardiovascular Examination for Respiratory Disease
106
2
Synthesis
108
3
Suggested Reading
109
2
Lung Sounds in Health and Disease
111
12
Raymond L.H. Murphy, Jr.
Robert G. Loudon
Classification of Lung Sounds
111
2
The Mechanisms That Produce Lung Sounds
113
4
Acute Respiratory Disorders
117
2
Chronic Respiratory Disorders
119
1
Observer Variability
120
1
Computer-Based Analysis
121
1
Conclusions
121
2
Suggested Reading
121
2
III. Common Diagnostic Studies: Principles and Interpretation
Pulmonary Function Testing
123
30
David A. Kaminsky
Introduction
123
3
Spirometry
126
7
Lung Volumes
133
3
Measures of Gas Exchange
136
3
Special Testing
139
4
Summary
143
2
Cases
145
8
Suggested Reading
150
3
Principles and Interpretation of the Chest Radiograph
153
16
Peter A. Dietrich
Todd Peebles
Role of the Chest Radiograph in the Evaluation of Patients with Respiratory Symptoms
153
1
Common Radiographic Techniques
153
1
An Approach to Chest Film Interpretation
154
6
Chest Radiographs in Selected Clinical Situations
160
7
Limitations of the Chest Film
167
2
Suggested Reading
168
1
Computed Tomography
169
30
Kevin K. Matsuba
Jeffrey S. Klein
General Utility of Computed Tomography of the Chest
169
1
Specific Diagnostic Problems
170
29
Suggested Reading
196
3
Bronchoscopy in Diagnosis and Management of Pulmonary Diseases
199
14
Michael Unger
Overview
199
1
Classification of Bronchoscopy
200
3
Indications for Diagnostic Bronchoscopy
203
3
Therapeutic Interventional Bronchoscopy
206
2
Complications
208
2
Summary
210
3
Suggested Reading
210
3
Diagnostic Sampling of Lung Tissues and Cells
213
8
Kevin O. Leslie
Louis A. Lanza
Richard A. Helmers
Thomas V. Colby
Introduction
213
1
Specimens from Bronchoscopy
213
3
Specimens from Transthoracic Needle Biopsy and Aspiration
216
1
Specimens from Thoracoscopy and Thoracotomy
217
4
Suggested Reading
218
3
IV. Common Diagnostic and Treatment Dilemmas
Dyspnea
221
12
Donald A. Mahler
Roberto Mejia
Introduction
221
1
What Is Dyspnea? What Causes Dyspnea?
221
2
Types of Dyspnea
223
1
Acute Dyspnea
224
1
Positional Dyspnea
225
2
Chronic Dyspnea
227
1
Treatment Strategies
228
3
Summary
231
2
Suggested Reading
231
2
Management of Cough
233
14
Richard S. Irwin
J. Mark Madison
Introduction
233
1
What Does Cough Mean to the Physician?
233
1
Why Do Patients with Cough Seek Medical Attention So Frequently?
234
1
What Has Been Learned About the Workup of Chronic, Persistent Cough?
235
2
What Protocols Are Recommended for Evaluating Cough?
237
2
What Is the Role of Empiric Therapy in Diagnosing the Cause of Chronic Cough?
239
3
What Has Been Learned About the Treatment of Chronic, Persistent Cough?
242
2
What are the Common Pitfalls in Managing Patients with Chronic Cough?
244
3
Suggested Reading
245
2
Chronic Rhinitis and Sinusitis
247
18
Sidney S. Braman
Anatomy and Physiology of the Nose and Paranasal Sinuses
247
3
Symptoms of Rhinitis and Sinusitis
250
2
Epidemiology of Rhinitis and Sinusitis
252
1
Chronic Rhinitis
253
6
Nasal Polyposis
259
1
Lung Function in Allergic Rhinitis
260
1
Nasal Hyperreactivity
261
1
Nasal Disease and Obstructive Sleep Apnea
261
1
Acute and Chronic Sinusitis
261
4
Suggested Reading
263
2
Pleural Effusion and Pneumothorax
265
28
Patrick A. Dowling
Veena B. Antony
Introduction
265
1
Pleural Effusion
265
21
Pneumothorax
286
7
Suggested Reading
290
3
Acute Lower Respiratory Tract Infection
293
16
Shawn J. Skerrett
Epidemiology of Acute Lower Respiratory Tract Infection
293
1
Microbiology of Acute Lower Respiratory Tract Infection
294
1
Clinical Presentation of Acute Lower Respiratory Tract Infection
295
1
Evaluation of Patients with Suspected Acute Lower Respiratory Tract Infection
296
6
Management of Acute Lower Respiratory Tract Infection
302
4
Prognosis and Follow-Up
306
3
Suggested Reading
306
3
Acute Respiratory Failure
309
20
John J. Marini
Introduction
309
1
Oxygenation Failure
309
9
Ventilatory Failure
318
6
Principles of Managing Respiratory Failure
324
5
Suggested Reading
326
3
Evaluation and Management of the Solitary Pulmonary Nodule
329
12
T. Glen Bouder
Jay H. Ryu
Introduction
329
2
Initial Evaluation
331
2
Diagnostic Procedures
333
3
Decision Making
336
2
Prognosis
338
1
Conclusion
338
3
Suggested Reading
339
2
Hemoptysis
341
16
David H. Ingbar
Introduction
341
1
Etiologies
341
11
Approach to Diagnosis and Management
352
2
Treatment
354
3
Suggested Reading
355
2
V. Common Therapies
Oxygen Therapy
357
14
Walter J. O'Donohue, Jr.
Introduction
357
1
Regulations and Requirements for Home Oxygen Therapy
357
2
Physician Responsibility in Long-Term Oxygen Therapy
359
1
Oxygen Reimbursement Issues
360
1
Oxygen During Sleep and Exercise
360
2
Oxygen Delivery Systems
362
1
Oxygen Concentrators
362
6
Conclusion
368
3
Suggested Reading
368
3
Smoking Prevention and Smoking Cessation
371
12
Roger H. Secker-Walker
Scope of the Problem
371
2
Smoking Prevention
373
1
Smoking Cessation
374
9
Suggested Reading
381
2
Lung Transplantation
383
30
James H. Dauber
Introduction
383
1
Definitions and Surgical Considerations
383
1
Diseases Amenable to Transplantation
384
2
Selection of Recipients
386
3
Selection of a Donor
389
2
Principles of Immunosuppression
391
3
Outcomes of Lung Transplantation
394
3
Complications
397
13
Summary
410
3
Suggested Reading
410
3
Principles of Mechanical Ventilation
413
16
Theodore W. Marcy
Goals of Mechanical Ventilation
413
1
Classification of Ventilator Modes
413
8
Ventilator Settings in Specific Clinical Settings
421
3
Evaluating for Discontinuation of Ventilatory Support
424
1
Long-Term Ventilation
425
4
Suggested Reading
426
3
VI. Important Specific Diseases
Asthma
429
22
William J. Calhoun
Introduction
429
1
Goals of Asthma Management
429
1
Approach to Asthma Diagnosis
430
6
Approach to Asthma Management
436
10
Specific Asthma Syndromes
446
2
Summary
448
3
Suggested Reading
449
2
Chronic Obstructive Pulmonary Disease and Emphysema
451
24
John W. Kreit
Robert M. Rogers
Introduction
451
1
Pathophysiology
451
2
Clinical Features
453
2
Diagnosis
455
2
Management of Stable COPD
457
10
Evaluation and Management of COPD Exacerbations
467
5
Conclusion
472
3
Suggested Reading
473
2
Sarcoidosis
475
12
Gunnar Gudmundsson
Gary W. Hunninghake
Introduction
475
1
Pathogenesis
475
2
Clinical Manifestations
477
1
Treatment
478
9
Suggested Reading
485
2
Chronic Diffuse Parenchymal Lung Diseases
487
44
Talmadge E. King, Jr.
Marvin I. Schwarz
Introduction
487
7
Occupational and Environmental Causes of DPLD
494
1
Drug-Induced Interstitial Lung Disease
494
2
Fibrotic Diseases of Unknown Etiology
496
16
Collagen Vascular Diseases
512
5
``Primary'' or Unclassified Syndromes
517
14
Suggested Reading
528
3
Venous Thromboembolism
531
20
Roger H. Secker-Walker
Venous Thromboembolism
531
3
Clinical Features
534
1
Diagnosis
535
3
Management
538
11
Summary
549
2
Suggested Reading
549
2
Sleep-Disordered Breathing
551
18
David E. Gannon
Introduction
551
1
Physiology of Sleep and Sleep-Disordered Breathing
551
2
Definitions
553
1
Risk Factors
554
1
Clinical Presentation
554
2
Clinical Evaluation of Patients
556
7
Management of Obstructive Sleep Apnea Syndrome
563
4
Conclusion
567
2
Suggested Reading
567
2
Lung Cancer
569
12
M. Patricia Rivera
Diane E. Stover
Epidemiology
569
1
Risk Factors/Etiology
569
1
Molecular Biology
570
1
Histology
571
1
Clinical Presentation
571
1
Paraneoplastic Syndromes
572
1
Diagnosis
572
1
Preoperative Assessment of NSCLC
573
3
Staging of SCLC
576
1
Natural History of Lung Cancer
577
1
Treatment of NSCLC
577
2
Treatment of SCLC
579
1
Prevention
580
1
The Future
580
1
Suggested Reading
580
1
Heart Disease Caused by Lung Disease
581
14
William E. Hopkins
Introduction
581
1
Pulmonary Hypertension
581
6
Parenchymal Lung Disease and Hypoxia
587
2
Pulmonary Vascular Occlusive Disease with Right Heart Failure
589
3
Pulmonary Vascular Occlusive Disease Without Right Heart Failure
592
3
Suggested Reading
593
2
Cystic Fibrosis
595
18
William P. Sexauer
Stanley B. Fiel
Introduction
595
1
Pathophysiology
595
2
Approach to the Patient
597
1
Antimicrobial Therapy
598
5
Chest Physiotherapy and Mucociliary Clearance
603
1
Bronchodilators and Aerosols
604
1
Mucolytics and DNase
604
1
Anti-Inflammatory Therapies
605
2
Lung Transplantation
607
1
Complications
608
3
Summary
611
2
Suggested Reading
612
1
Tuberculosis
613
14
Jeffrey D. Edelman
Milton D. Rossman
Introduction
613
1
Clinical Presentation of Tuberculosis
613
2
Diagnosis of TB Infection
615
2
Tuberculin Skin Testing and Prophylaxis
617
2
Treatment of Active Tuberculosis
619
4
Prevention of Transmission
623
4
Suggested Reading
624
3
Infections Due to Nontuberculous Mycobacteria
627
12
Michael D. Iseman
Introduction
627
1
Various Forms of Pulmonary Disease
627
3
Diagnosis of Pulmonary NTM Infection
630
1
Principles of Treatment
631
2
Adjunctive Therapy
633
1
Common Pathogens
633
4
Recommended Management
637
2
Suggested Reading
638
1
Chronic Fungal Pulmonary Infections
639
14
Scott F. Davies
Introduction
639
1
Histoplasmosis
640
2
Blastomycosis
642
2
Coccidiodomycosis
644
3
Cryptococcosis
647
1
Aspergillosis
648
5
Suggested Reading
652
1
VII. Respiratory Disease in Special Settings
Occupational and Environmental Airway Disease
653
14
Joel N. Kline
David A. Schwartz
Introduction
653
1
Occupational History
654
1
Occupational Asthma
655
4
Chronic Airway Disease-Chronic Obstructive Pulmonary Disease, Industrial Bronchitis, and Byssinosis
659
1
Toxic Fumes
660
3
Reactive Airways Dysfunction Syndrome (RADS)
663
1
Organic Dust Toxic Syndrome (ODTS)
664
2
Management and Outcome
666
1
Suggested Reading
666
1
Occupational and Environmental Lung Diseases Caused by Inhaled Particles and Fibers
667
30
Gerald S. Davis
Diagnosis of Occupational Parenchymal Lung Diseases
667
3
Dose, Time, Exposure, and Biological Response
670
3
Lung Diseases Caused by Inhaled Particles
673
11
Lung Diseases Caused by Inhaled Fibers
684
6
Lung Diseases Caused by Cobalt
690
4
Lung Diseases Caused by Beryllium
694
1
Conclusions
695
2
Suggested Reading
695
2
Hypersensitivity Pneumonitis
697
16
Gerald S. Davis
Clinical Features
697
4
Agents and Environmental Exposures
701
4
Pathogenesis
705
2
Prevalence
707
1
Diagnosis
707
2
Prognosis
709
1
Therapy
709
4
Suggested Reading
710
3
Evaluation of Respiratory Impairment and Disability
713
8
Akshay Sood
Carrie A. Redlich
Introduction
713
1
Basic Definitions
713
1
Guidelines for Disability Evaluation
714
1
Clinical Approach to Evaluating Pulmonary Disability
714
2
Evaluation of Common Diseases
716
3
Workmen's Compensation
719
1
Reporting Disability and Compensation Evaluations
720
1
Suggested Reading
720
1
Altitude and Illness
721
14
William G.B. Graham
Introduction
721
1
General Adaptive Mechanisms in Normals
722
2
Altitude and Illness
724
1
Acute Mountain Sickness
725
1
High-Altitude Pulmonary Edema (HAPE)
726
1
High-Altitude Cerebral Edema
727
1
Altitude and Existing Lung Disease
728
1
Lung Disease and Adaptation to Altitude
728
2
Aircraft Flight
730
5
Suggested Reading
732
3
Obesity
735
16
Dudley F. Rochester
Introduction
735
1
Quantification and Distribution of Obesity
735
2
Gas Exchange and Pulmonary Function
737
1
Respiratory System Compliance and Resistance
738
1
Control of Breathing
738
1
Respiratory Muscle and Exercise Performance
739
1
Clinical Complications Related to the Respiratory System
740
3
Weight Loss in Morbid Obesity
743
1
Treatment of OSA and Ventilatory Failure
744
2
Case Presentation
746
1
Summary
747
4
Suggested Reading
748
3
Pregnancy
751
18
Jing W. Liu
Dudley F. Rochester
Introduction
751
1
Respiratory Physiology in Pregnancy
751
3
Obstructive Lung Diseases
754
4
Restrictive Disorders of the Lungs and Chest Wall
758
1
Infectious Diseases
759
3
Acute Respiratory Failure
762
2
Deep Venous Thrombosis and Pulmonary Embolism
764
5
Suggested Reading
767
2
Preoperative Evaluation and Management of the Respiratory Disease Patient
769
14
Simon D. Spivack
Joseph L. Saraceno
The Surgical Procedure as a Challenge to the Respiratory Disease Patient
769
1
Anesthesia
769
2
Site-Specific Risks for Surgery
771
6
Perioperative Interventions That Minimize Risk
777
1
Smoking Cessation
777
1
Lung Expansion Techniques
778
2
Management of Airflow Obstruction
780
1
Prophylaxis Against Deep Vein Thrombosis
780
3
Suggested Reading
781
2
Index
783