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Tables of Contents for Introducing Genetics
Chapter/Section Title
Page #
Page Count
Introduction
1
6
Key concepts in genetics
3
4
Monohybrid inheritance
7
13
Key principles of genetic inheritance
8
2
A genetic explanation of the monohybrid cross
10
1
Representing genetic crosses
11
1
A Punnett Square
12
1
Mendel's first law of segregation
13
1
Predicting the outcome of crosses
14
1
Chance and probability in genetics
15
1
The importance of large numbers
16
1
The test cross
17
3
Problems
19
1
Extensions to monohybrid inheritance
20
18
Multiple allelism
21
2
Incomplete dominance
23
2
Representing crosses involving incomplete dominance
25
1
Explaining incomplete dominance
26
1
Redefining dominance relationships
26
2
Codominance
28
1
Lethal alleles
29
2
Are lethal alleles recessive or dominant?
31
1
Human pedigrees
31
3
The multiplication rule
34
4
Problems
36
2
Dihybrid inheritance
38
20
Two genes--two characters
39
3
Test cross
42
1
Mid-chapter summary
42
2
Two genes -- one trait
44
3
Complementary genes
47
4
Epistasis
51
3
The chi-squared (χ2) test
54
4
Problems
57
1
The chromosomal basis of inheritance
58
16
The structure of chromosomes
59
2
The number of chromosomes
61
1
Homologous pairs of chromosomes
62
1
Diploid and haploid cells
62
1
Two types of nuclear division
63
1
Mitosis
63
3
The biological significance of mitosis
66
1
Meiosis
67
1
The biological significance of meiosis
68
2
Revisiting Mendel's laws
70
4
Problems
73
1
Sex determination and sex linkage
74
15
Sex-determining chromosomes
75
1
Other sex-determining mechanisms
76
2
The Y chromosome and sex determination in humans
78
1
The expression of X-linked genes
79
1
Representing crosses involving X-linked genes
80
1
Sex-linked inheritance patterns
80
2
Pedigree analysis of human X-linked recessive inheritance
82
2
Human X-linked dominant inheritance
84
1
Inactivation of the X chromosome
85
1
Y-linked inheritance
86
3
Problems
88
1
Linkage and chromosome mapping
89
15
The discovery of linkage
90
3
Representing dihybrid crosses involving linked genes
93
1
Explaining Bateson and Punnett's sweet pea results
93
2
The use of the test cross in linkage studies
95
2
Producing chromosomal maps
97
4
A few comments on physical mapping
101
3
Problems
103
1
Variation in chromosomal number and structure
104
17
Changes in chromosome number: terminology
105
1
Aneuploidy
106
1
Monosomy
107
1
Trisomy
107
3
Polyploidy
110
1
Origins of polyploidy
111
1
Producing an autopolyploid
111
1
Producing an allopolyploid
112
2
Changes in chromosome structure
114
1
Changes in the arrangement of genes
115
3
Changes in the number of genes on a chromosome
118
3
Problems
120
1
The principles of quantitiative genetics
121
19
Multifactorial traits: some definitions
122
1
Representing multifactorial traits
123
1
Calculating the mean
124
2
Calculating the variance
126
1
Calculating the standard deviation
127
1
Genes or environment?
128
1
Partitioning phenotypic variance
128
3
Heritability index
131
1
Partitioning genetic variance
132
2
Narrow sense heritability
134
1
Investigating multifactorial traits in humans
134
6
Problems
138
2
An introduction to population genetics
140
17
Population genetics: some definitions
141
1
Calculating allele frequencies
142
1
The Hardy--Weinberg law
143
2
Calculating genotype frequencies
145
1
Testing for equilibrium
146
1
Disturbances of the Hardy--Weinberg equilibrium
147
1
Mutation
148
1
Migration
149
1
Genetic drift: random changes in small populations
150
2
Selection
152
5
Problems
156
1
Heredity at the molecular level
157
11
The structure of DNA -- a summary
158
1
The biochemical nature of nucleotides
158
1
The double helix
159
2
DNA coiling
161
1
Replicating DNA
162
2
Molecular details of DNA replication
164
4
Problems
167
1
From genes to proteins
168
15
Information flow from gene to protein -- a summary
170
1
The biochemical nature of RNA
170
1
Producing RNA: transcription
171
1
The different forms of RNA
172
1
Exons and introns
173
1
The genetic code
174
2
Producing the protein: translation
176
2
Causes and consequences of mutation
178
5
Problems
182
1
Manipulating genes
183
14
An overview of recombinant DNA technology
184
1
Restriction enzymes
184
1
Vectors
185
2
Creating a recombinant DNA molecule
187
1
Introducing the recombinant DNA molecule into a host cell
187
2
The production of human recombinant proteins
189
3
The production of transgenic crops
192
5
Glossary
197
6
Further reading
203
1
Solutions to problems
204
10
Index
214