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Tables of Contents for Neurobiology of the Immune System
Chapter/Section Title
Page #
Page Count
Contributors
xi
Preface
xiii
Neuroimmune Relationships in Perspective
Frank Hucklebridge
Angela Clow
Introduction
1
1
Innate and Acquired Immunity
2
7
The Neuroendocrine System and the Balance of the Immune System
9
5
Conclusions
14
3
Sympathetic Nervous System Interaction with the Immune System
Virginia M. Sanders
Adam P. Kohm
Introduction
17
1
Anatomy and Physiology
18
3
Adrenergic Receptor Expression on Immune Cells
21
4
Effect of β2AR Stimulation on CD4+ T Lymphocytes
25
3
Effect of β2AR Stimulation on B Lymphocytes
28
3
Conclusion
31
12
References
32
11
Mechanisms by Which Cytokines Signal the Brain
Adrian J. Dunn
Introduction
43
6
Interleukin-1 (IL-1)
49
9
Conclusions
58
9
References
59
8
Neuropeptides: Modulators of Immune Responses in Health and Disease
David S. Jessop
Introduction
67
1
CRH and Related Peptides
68
2
Pro-opiomelanocortin (POMC) Peptides
70
5
Opioid Peptides Other Than β-Endorphin
75
4
Trophic Peptides
79
1
Other Immunoneuropeptides
80
1
Quantitative Analysis of Immunoneuropeptides by MACS
81
1
Conclusions
82
11
References
84
9
Brain--immune Interactions in Sleep
Lisa Marshall
Jan Born
Sleep
93
5
Microbial Products and Cytokines: A Brief Overview
98
4
Effects of Microbial Products and Cytokines on Sleep
102
9
Effect of Sleep--Wake Activity on Cytokines and the Immune System
111
10
Summary
121
12
References
123
10
Neuroendocrinology of Autoimmunity
Michael Harbuz
Introduction
133
1
The Hypothalamic-Pituitary-Adrenal (HPA) Axis
134
4
The HPA Axis in Autoimmune Disease
138
13
Neurotransmitters in Disease
151
3
Summary
154
9
References
155
8
Systemic Stress-Induced Th2 Shift and Its Clinical Implications
Ilia J. Elenkov
Introduction
163
1
Th1/Th2 Paradigm: Role of Type 1 and Type 2 Cytokines
164
2
Stress Hormones and Th1/Th2 Balance
166
5
Clinical Implications
171
8
Conclusions
179
8
References
180
7
Neural Control of Salivary S-IgA Secretion
Gordon B. Proctor
Guy H. Carpenter
Introduction
187
2
Nerve-Mediated Increases in Salivary Secretion of S-IgA
189
3
Autonomimetic Stimulation of pIgR-Mediated IgA Transcytosis
192
7
Studies of Reflex IgA Secretion
199
5
Long-Term Influences of Nerves on S-IgA Secretion
204
2
Effects of Nerves on Plasma Cell Production of IgA
206
2
Conclusion
208
6
References
208
6
Stress and Secretory Immunity
Jos A. Bosch
Christopher Ring
Eco J. C. De Geus
Enno C. I. Veerman
Arie V. Nieuw Amerongen
Introduction
214
1
Saliva as a Model for Mucosal Secretory Defense
215
1
An Outline of Secretory Immunity
216
2
The Neurobiological Basis for Stress-Induced Changes in Salivary Secretory Immunity
218
5
Stress and Secretory IgA
223
17
Stress and Innate Secretory Immunity
240
2
Stress and Microbial Colonization Processes
242
1
Future Perspectives
243
12
References
245
10
Cytokines and Depression
Angela Clow
Introduction
255
1
Depression and Immune System Dysregulation
256
4
Neuroendocrine Dysregulation
260
2
Relationship between Immune and Neuroendocrine System Changes
262
1
Effect of Cytokines on Mood
263
1
Role of Brain Monoamines
264
3
Conclusions
267
8
References
268
7
Immunity and Schizophrenia: Autoimmunity, Cytokines, and Immune Responses
Fiona Gaughran
Background
275
2
Autoimmune Diseases and Schizophrenia
277
4
T and B Lymphocytes in Schizophrenia
281
7
HLA Antigens in Schizophrenia
288
1
HPA Axis in Schizophrenia
289
1
Effects of Antipsychotic Medication
290
1
Treatment of Schizophrenia with Immunosuppressants
291
1
Vaccine Response
291
1
Th1/Th2 Imbalance in Schizophrenia
292
2
Summary
294
9
References
294
9
Cerebral Lateralization and the Immune System
Pierre J. Neveu
Introduction
303
2
Opposite Effects of Left- and Right-Cortical Ablations on Immunity
305
4
Association between Behavioral Lateralization and Immune Reactivity
309
8
General Conclusion and Perspectives
317
8
References
318
7
Behavioral Conditioning of the Immune System
Frank Hucklebridge
Introduction
325
7
Conditioned Immunosuppression Using Cyclosporin A
332
3
Conditioned Immunopotentiation
335
3
Antigen as the Unconditioned Stimulus
338
4
Human Studies
342
5
Conclusions
347
6
References
348
5
Psychological and Neuroendocrine Correlates of Disease Progression
Julie M. Turner-Cobb
Introduction
353
2
Psychological Correlates Associated with Disease Progression
355
8
Intervention Studies
363
1
Neuroendocrine and Immunological Correlates That Underpin Disease Progression
364
5
Neuroimmune Alterations Associated with Psychological Interventions
369
3
Other Explanatory Mechanisms in Disease Progression
372
11
References
373
10
The Role of Psychological Intervention in Modulating Aspects of Immune Function in Relation to Health and Well-Being
J. H. Gruzelier
Introduction
383
1
Relaxation Training
384
4
Guided Imagery of the Immune System
388
15
Hypnosis and Immunity
403
3
Research Directions
406
13
References
412
7
Index
419
14
Contents of Recent Volumes
433