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Tables of Contents for The Human Genome
Chapter/Section Title
Page #
Page Count
Acknowledgments
ix
Preface
xi
SECTION 1 The Basics of Heredity
1
44
Slaying Molecular Dragons: Brenda's Tale
3
4
The Answer In A Nutshell: Genes, Proteins, and the Basis of Life
7
8
Mendel and the Concept of the Gene
15
10
Human Mendelian Genetics
25
12
One Man's Trait Is Another Man's Disease
37
8
SECTION 2 The Central Dogma of Molecular Biology
45
40
DNA: The Genetic Alphabet
47
8
The Central Dogma of Molecular Biology: How Genes Encode Proteins
55
10
Splicing the Modular Gene
65
6
Orchestrating the Human Genome
71
14
SECTION 3 How Chromosomes Move
85
40
So What are Chromosomes Anyway?
87
8
How Cells Move Your Genes Around
95
12
Passing Genes Between Generations
107
10
The Chromosomal Basis of Heredity
117
8
SECTION 4 Mutation
125
78
Absent Essentials and Monkey Wrenches
127
12
How We Detect Mutations
139
14
We Are All Mutants
153
16
What Constitutes Normal?
169
8
Mutations in Mammoth Genes
177
10
Expanded Repeat Traits
187
16
SECTION 5 Genes, Chromosomes, and Sex
203
50
The X and Y Chromosomes: The Odd Couple
205
10
Genetics of Sex, Gender, and Orientation
215
22
Aneuploidy: When Too Much or Too Little Counts
237
16
SECTION 6 Breaking the Rules
253
24
Imprinting
255
10
Imitating Heredity: One Trait, Many Causes
265
12
SECTION 7 The Human Genome Landscape
277
48
The Human Genome Project
279
8
There's Cloning and Then There's Cloning
287
12
The Human Genome Sequence
299
12
Finding Genes in the Human Genome
311
14
SECTION 8 Complex and Heterogeneous Traits
325
52
Genotype Phenotype Correlations
327
10
How Complex Can It Get?
337
8
Quantitative Traits
345
8
The MAOA Gene: Is There a Genetic Basis for Criminality?
353
6
The Multiple-Hit Hypothesis: The Genetics of Cancer
359
18
SECTION 9 Genetic Testing and Therapy
377
42
Genetic Testing and Screening
379
24
Magic Bullets: The Potential for Gene Therapy
403
16
SECTION 10 Fears, Faith, and Fantasies
419
22
Heroes Among Us
421
8
Fears, Faith, and Fantasies
429
12
Credits
441
10
Index
451