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Tables of Contents for Pathology and Pathogenesis of Human Viral Disease
Chapter/Section Title
Page #
Page Count
Preface
xv
Acknowledgments
xvii
Enteroviruses
Introduction
1
1
Virology and Epidemiology
2
1
Neurological Disease
3
7
Aseptic Meningitis
3
1
Encephalitis
4
1
Polimyelitis
4
2
Post-Poliomyelitis Syndrome (PPS)
6
2
Chronic CNS Infection in the Immunocompromised Patient
8
2
Heart Disease
10
6
Clinical Diagnostic Criteria
10
1
Pathological Diagnostic Criteria: The ``Dallas'' Criteria
11
2
Enterovirus Etiology
13
1
Natural History of Group B Coxsackievirus Myocarditis
13
1
Pathogenic Mechanisms
14
2
Striated Muscle Disease
16
1
Epidemic Myalgia: Pleurodynia, Bornholm Disease
17
1
Lung Disease
18
1
Testicular Disease
18
1
Liver Disease
19
1
Kidney Disease
19
1
Placental Lesions of Neonatally Infected Infants
20
1
Skin and Mucus Membrane Disease
20
1
Type I Diabetes Mellitus
21
14
Rhinoviruses
Influenza Viruses
Influenza Viruses
35
4
Risk Factors
39
1
Lung Disease
40
1
Heart Disease
41
2
Muscle Disease
43
1
Salivary Gland Disease
43
1
Central Nervous System Disease
43
1
Reye-Johnson Syndrome
43
18
Parainfluenza Viruses
Respiratory Syncytial Virus (RSV)
Herpesviruses: General Principles
Introduction
61
1
Cellular Virus Replication
61
1
Herpesvirus Latency
62
1
Herpesvirus Cytopathology (Alpha and Beta)
63
2
Herpes Simplex Virus (HSV) Types 1 and 2
Introduction
65
1
Primary and Recurrent Oral and Skin Infections
65
1
Urogenital Tract Disease
66
3
Generalized Systemic Disease
69
2
Central Nervous System Disease
71
4
Respiratory Tract Disease
75
1
Digestive Tract Disease
76
1
Liver Disease
77
1
Lymph Node Disease
78
1
Eye Disease
78
9
Cytomegalovirus
Historical Overview
87
1
Cytomegalic Inclusion Body Cells
88
1
Epidemiology and Natural History
89
1
Congenital CMV Infection and Disease
90
2
Placental Infection and Diseases
92
1
Infections of Immunologically Intact Children and Adults
92
1
Mononucleosis and the Posttransfusion Syndrome
93
1
Nervous System Infection and Disease
93
3
Pulmonary Infection and Disease
96
4
Digestive Tract Infection and Disease
100
1
Liver Infection and Disease
101
1
Pancreas Infection and Disease
102
1
Genitourinary Tract Infection and Disease
102
3
Myocardial Infection and Disease
105
1
Eye Disease
106
1
Ear Disease
107
1
Possible Role of CMV in Atherosclerosis
107
10
Epstein-Barr Virus (EBV)
Introduction and Historical Overview
117
1
Cellular and Molecular Biology of EBV
118
2
Infectious Mononucleosis (IM)
120
3
Neuromuscular Disease
122
1
Myocarditis and Pericarditis
123
1
Kidney Disease
123
1
Lower Female Genital Tract
123
1
X-Linked Lymphoproliferative Disease (XLP) (Duncan's Disease)
123
1
Burkitt's Lymphoma (BL)
124
3
Lymphoproliferative Disorders (LPDs) Associated with Immunosuppression
127
2
Non-Hodgkin's Lymphoma
129
1
Hodgkin's Disease (HD)
130
1
Nasopharyngeal Carcinoma (NPC)
131
2
Lymphoepitheliomatous Gastric Carcinoma
133
1
Sinonasal Tumors
133
1
Pulmonary Disease
134
1
Lymphomatoid Granulomatosis
135
1
Inflammatory Pseudotumors
135
1
Sjogren's Syndrome and Salivary Gland Tumors
135
1
Hairy Leukoplakia (HCL)
136
2
Virus-Associated Hematophagocytic Syndrome
138
9
Varicella-Zoster Virus (VZV)
Introduction and Historical Overview
147
1
Disseminated Childhood VZV Infection of the Skin: Chickenpox
147
2
Hemorrhagic VZV Infections of the Skin
149
1
Chronic VZV Infections of the Skin
150
1
Nervous System Disease
151
5
Herpes Zoster
151
3
Encephalopathies
154
2
Eye Disease
156
2
Ear Disease
158
1
Pulmonary Disease
158
1
Digestive Tract Disease
159
1
Liver Disease
159
1
Renal Disease
160
2
Testicular Disease
162
1
Heart Disease
162
1
Joint, Synovial, and Muscle Diseases
162
1
Congenital VZV Infection
162
9
Herpesvirus Type 6 (HHV-6)
Kaposi Sarcoma-Associated Herpesvirus (KSHV, HHV-8)
Introduction
171
2
Epidemiology
173
1
Pathogenesis and Pathology
174
4
Angiosarcomas and Other Vascular Lesions
178
1
Body Cavity-Based Non-Hodgkin's Lymphoma (BCBL)
178
2
Angiofollicular Lymph Node Hyperplasia
180
9
Herpesvirus Simiae Virus (Herpes B)
Adenoviruses
Introduction
189
1
Epidemiology
189
2
Respiratory Tract Disease
191
4
Disease in Immunosuppressed Patients
195
1
Genitourinary Tract Disease
196
1
Digestive Tract Disease
197
1
Myocardial Disease
197
1
Central Nervous System Disease
197
1
Eye Disease
198
7
Retroviruses: General Principles
Human Immunodeficiency Viruses
Human Immunodeficiency Viruses 1 and 2 (HIV-1 and HIV-2)
205
2
HIV-1 Clinical Course in Adults
207
3
HIV-1 Clinical Course in Infants and Children
210
2
Persistent Generalized Lymphadenopathy (PGL) (syn. Progressive Generalized Lymphadenopathy)
212
3
Diseases of the Hematopoietic System
215
1
Diseases of the Central Nervous System
216
6
Acute Meningitis
216
1
Acute Meningitis
216
1
HIV-1 Encephalopathy
216
1
Cognitive/Motor Complex (Syn. Dementia Complex)
217
2
Myelopathy and Myelitis
219
1
Neuropathy
219
1
Myositis
220
1
Opportunistic CMV Infections of the Central and Peripheral Nervous Systems
221
1
Diseases of the Respiratory Tract
222
4
Diffuse Alveolar Damage (DAD)
222
1
Lymphoid Interstitial Pneumonia (LIP), Nonspecific Interstitial Pneumonia (NIP), Follicular Bronchitis/Bronchiolitis (FBB)
222
1
Pulmonary Hypertension and Vascular-Occlusive Disease
223
2
Opportunistic Infections of the Lung
225
1
Diseases of the Heart
226
1
Diseases of the Vasculature
227
1
Diseases of the Kidney
228
1
Diseases of the Testis
229
1
Diseases of the Digestive Tract
230
1
Tubuloreticular Structures (TRSs) and Cylindrical Confronting Cisternae (CCC)
231
1
Lymphomas
231
1
Kaposi's Sarcoma
232
2
Cervical Cancer
234
9
Human T Cell Leukemia/Lymphoma Viruses (HTLV-1 and-2)
Introduction
243
1
T Cell Leukemia/Lymphoma (TLL) Syndrome
244
3
Tropical Spastic Paraparesis (TSP)
247
1
Inflammatory Conditions Associated with HTLV-1 Infection
248
1
HTLV-2
249
4
Hepatitis Viruses
Introduction
253
1
Orally Acquired Short-Incubation-Period Acute Hepatitis
254
3
Hepatitis A Virus (HAV)
254
1
Hepatitis E Virus (HEV)
255
2
Parentally Acquired Long-Incubation-Period Acute and Chronic Hepatitis
257
5
Hepatitis B Virus (HBV)
257
3
Hepatitis D Virus (HDV) (Delta Agent)
260
1
Hepatitis C Virus (HCV)
260
2
Chronic Hepatitis (CH)
262
2
Hepatocellular Carcinoma (HCC)
264
6
Autoimmune Hepatitis (AH)
270
1
Papillary Acrodermatitis (Gianotti-Crosti Syndrome; GCS)
271
1
Glomerulonephritis
272
5
Hemorrhagic Fever Viruses
Introduction
277
1
Arenaviruses
277
5
Argentinian and Bolivian Hemorrhagic Fevers
278
2
Venezuelan and Sao Paulo Hemorrhagic Fever
280
1
West African Hemorrhagic Fever (Lassa Virus)
280
2
Bunyaviruses
282
5
Hemorrhagic Fever With Renal Disease
282
3
Rift Valley Fever (RVF)
285
1
Crimean-Congo Hemorrhagic Fever (CCHF)
286
1
Filoviruses
287
2
Marburg Virus Disease
287
1
Ebola Virus
287
2
Flaviviruses
289
14
Yellow Fever
290
2
Dengue
292
1
Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS)
293
10
Hantavirus Pulmonary Syndrome (HPS)
Papillomaviruses
Introduction
303
2
Disease of the Skin
305
3
Disease of the Female Genital Tract
308
6
Vulva and Vagina
309
2
Cervix Uteri
311
3
Endometrium
314
1
Disease of the Glans Penis
314
1
Disease of the Digestive Tract
315
2
Oropharynx
315
1
Esophagus
315
2
Anus
317
1
Disease of the Larynx and Tracheobronchial Tree
317
4
Disease of the Eye
321
1
Disease of the Middle Ear
322
5
Papovaviruses
Introduction
327
2
Progressive Multifocal Leukoencephalopathy (PML)
329
2
Urinary Tract Infection and Disease
331
4
Parvoviruses
Introduction
335
2
Joint Disease
337
1
Erythropoietic Systemic Disease
337
2
Infections in Pregnancy
339
1
Inflammatory Lesions
340
1
Tissue Diagnosis
340
3
Neurotropic Arthropod-Transmitted Viruses
Introduction
343
1
Togaviruses (Alphaviruses)
344
5
Eastern Equine Encephalitis (EEE)
346
1
Western Equine Encephalitis (WEE)
347
1
Venezuelan Equine Encephalitis (VEE)
348
1
Flaviviruses
349
5
St. Louis Encephalitis (SLE)
351
1
Japanese B Encephalitis (JBE)
352
1
Other Flavivirus Encephalitides
353
1
Bunyaviruses
354
1
LaCrosse (California Encephalitis Group)
354
1
Reoviruses
354
3
Rabiesviruses
Introduction
357
1
Epidemiology
357
1
Clinical Disease
358
1
Pathogenesis
359
1
Central Nervous System Disease
360
5
Poxviruses
Introduction
365
1
Orthopoxviruses
366
9
Variola (Major and Minor)
367
4
Vacciniavirus
371
2
Monkeypox
373
2
Parapoxviruses
375
2
Milker's Nodules
377
1
Bovine Papular Stomatitis (BPS)
377
1
Ecthyma Contagiosum (orf)
377
1
Molluscipoxviruses
377
4
Mumps
Introduction
381
1
Salivary Gland Disease
382
1
Central Nervous System Disease
382
1
Testicular Disease
383
1
Pancreatic Disease
384
1
Mumps-Associated Diabetes Mellitus
385
1
Ear Disease
386
1
Joint Disease
386
3
Rubellavirus
Introduction
389
1
Naturally Acquired Postnatal Infections
390
1
Congenitally Acquired Infections
391
6
Rubeola (Measles)
Introduction
397
2
Respiratory Tract Disease
399
3
Atypical Measles Syndrome
402
1
Central Nervous System Disease
403
4
Meningoencephalitis After Natural Infection
403
1
Meningoencephalitis in the Immunosuppressed Patient
403
1
Meningoencephalitis After Measles Vaccine
404
1
Subacute Sclerosing Panencephalitis (SSPE)
404
3
Middle Ear Disease
407
1
Eye Disease
407
1
Pregnancy
407
4
Transmissible Spongiform Encephalopathy
Introduction
411
1
Scrapie
412
1
Human Spongiform Encephalopathies: Clinical Features
412
3
Creutzfeldt-Jakob Disease (CJD)
413
1
Gerstmann-Straussler-Scheinker Disease (GSS)
414
1
Kuru
414
1
Fatal Familial Insomnia (FFI)
415
1
Human Spongiform Encephalophathies: Pathological Features
415
2
Prions (Protein Infectious Organisms)
417
4
New Variant CJD (vCJD)
421
1
Iatrogenic CJD
422
1
Precautions for Pathologists
422
2
Ancillary Nonhistopathological Diagnostic Approaches of the Prion Diseases
424
7
Lymphocytic Choriomeningitis Virus (LCMV)
Enteric Viral Disease
Introduction
431
1
Norwalk-Like Viruses (NLVs)
432
1
Rotaviruses (RVs)
433
5
Additional Enteric Viruses
438
1
Pathophysiology of Viral Enteritis
439
2
Index
441