Product Description: Surfing is sixteen-year-old Iris's world, and when the ultra-talented Zeke walks into her life, it soon becomes her passion. Over one amazing summer, as she is drawn into his sphere, she experiences love, new friendships, but also loss, with an intensity she never dreamed of...read more

Product Description: This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques...read more

Product Description: Understanding space is perhaps the key to understanding Earth, and this book about far away planets is contrasts them to our Earth and explains much about our origin, our solar system, and the thrill of outer space. It also describes the technology that supports research into our universe today...read more

Product Description: When the late Professor C. D. Darlington founded what developed into the International Chromosome Conferences in Oxford in 1964, he was concerned that scientists who worked on different aspects of chromosomes, or who studied them in different ways, should have the opportunity of "discussing the fundamental problems of chromosomes with one another"...read more

Product Description: Chromosome Painting is the most modern and novel technique for directly identifying several gene sequences simultaneously in the chromosome, with the aid of specific probes in molecular hybridization. Its resolution ranges from single copy to entire genome sequences...read more

Product Description: Chromosomale Mutationen sind eine der m|glichen Ursachen f}r Ver{nderungen der Erbinformation. Neben grunds{tzlichen As- pekten, wie Reparaturmechanismen der Zelle oder Ursachen von Chromosomenver{nderungen, werden angewandte Aspekte, z...read more

Product Description: Chromosomes have structure, determined by the interactions of proteins with DNA, and chromosomes have functions, in particular, replication of DNA and transcription of messenger RNA. Chromosome structure and function are not separate topics, since chromosome organization pro­ foundly influences the activity of the genome in replication and transcrip­ tion...read more

Product Description: Proceedings of the NATO Advanced Research Workshop on Chromosome Segregation and Aneuploidy, held at Aghia Pelagia, Greece, October 10-15, 1992

Product Description: A Historical Perspective on the Study of Chromosome Structure and Function R. Appels Division of Plant Industry CSIRO P.O. Box 1600 A.C.T. AUSTRALIA "Modern physical science gives us no model to explain the re­ duplication of the gene-string in each cell generation, or to ex­ plain the production of effective quantities of specific enzymes or other agents by specific genes...read more

Product Description: A book that constitutes the first attempt to comprehensively assemble current knowledge of different types of such elements, highlight recent developments in the field, and challenge the distinction between viruses and linear plasmids...read more

Product Description: For both volumes: Expert investigators describe not only the classic methods, but also the many novel techniques they have perfected for the transfer of large DNAs into the cells of both microbes and animals via large-insert recombinant DNAs...read more

Covering various questions parents ask about the causes, characteristics and diagnosis of Down Syndrome, this edition includes the difficult issues around prenatal tests. It deals with the early reactions and feelings that parents may have and how the family adapts and copes when a child is diagnosed with Down Syndrome.

Product Description: Kinetochores orchestrate the faithful transmission of chromosomes from one generation to the next. Kinetochores were first depicted over 100 years ago, but kinetochore research has progressed by leaps and bounds since the first description of their constituent DNA and proteins in the 1980s...read more

Product Description: The 2005 Workshop, published as volume 1061 of the Annals, focused on testicular cell dynamics and brought an influx of new information into the field of male reproduction. Several laboratories have been actively investigating the endocrine signals between the germ and somatic cells of the testis, revealing previously unknown patterns of cell signaling and cell-to-cell communication in male reproductive tract tissues...read more

Integrating classical knowledge of chromosome organisation with recent molecular and functional findings, this book presents an up-to-date view of chromosome organisation and function for advanced undergraduate students studying genetics. The organisation and behaviour of chromosomes is central to genetics and the equal segregation of genes and chromosomes into daughter cells at cell division is vital. This text aims to provide a clear and straightforward explanation of these complex processes. Following a brief historical introduction, the text covers the topics of cell cycle dynamics and DNA replication; mitosis and meiosis; the organisation of DNA into chromatin; the arrangement of chromosomes in interphase; euchromatin and heterochromatin; nucleolus organisers; centromeres and telomeres; lampbrush and polytene chromosomes; chromosomes and evolution; chromosomes and disease, and artificial chromosomes. Topics are illustrated with examples from a wide variety of organisms, including fungi, plants, invertebrates and vertebrates. This book will be valuable resource for plant, animal and human geneticists and cell biologists. Originally a zoologist, Adrian Sumner has spent over 25 years studying human and other mammalian chromosomes with the Medical Research Council (UK). One of the pioneers of chromosome banding, he has used electron microscopy and immunofluorescence to study chromosome organisation and function, and latterly has studied factors involved in chromosome separation at mitosis. Adrian is an Associate Editor of the journal Chromosome Research, acts as a consultant biologist and is also Chair of the Committee of the International Chromosome Conferences. The most up-to-date overview of chromosomes in all their forms. Introduces cutting-edge topics such as artificial chromosomes and studies of telomere biology. Describes the methods used to study chromosomes. The perfect complement to Turner.

Product Description: This fascinating volume addresses the processes and mechanisms taking place in the cell during meiosis and recombination. It covers multicellular eukaryotes such as Drosophila, Arabidopsis, mice and humans. Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II – reducing chromosome number from the diploid level to a haploid genome, reshuffling the homologous chromosomes by their centromeres, and recombining chromosome arms by crossing-over...read more

Product Description: The goal of this book is neither to provide a basic introduction to imprinting, nor to provide a comprehensive survey of the current state of the field. Rather, the book covers more recent advances, drawing attention to the emerging subtleties and complexities associated with imprinted genes...read more

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Product Description: 2006 marked the 50th anniversary of the discovery of the human chromosome number, establishing human cytogenetics as a scientific discipline and setting the basis for modern medical genetics. First Years of Human Chromosomes draws together the ground-breaking work of the main researchers in the key period 1955 to 1960...read more

The geneticist-author of The Seven Daughters of Eve offers a close-up study of the defining characteristic of men, and the Y chromosome in their DNA, and explains why this could be men's fatal flaw, drawing on the latest research in a variety of scientific fields to explore such issues as the potential for a male homosexual gene and the genetic causes of male aggression. (view table of contents)

Product Description: One Hundred Years of Chromosome Research: What Remains to be Learned, offers the reader a critical analysis of the observations and experiments that shaped the last 100 years of chromosome research, as well as the ideas which prevailed during this period...read more