Product Description: Complex metabolic pathway diagrams are a hallmark of many biochemistry textbooks. But what do they tell us about disease, physiology, cell signaling, aging, immunity, and gene expression? In a refreshing approach to the subject of metabolism, Navigating Metabolism provides a conceptual framework for navigating these pathways, showing how cells generate energy and synthesize cellular constituents and then further relating metabolic reactions to molecular, genetic, and signaling underpinnings...read more

Product Description: A variety of metabolic processes are known to be intimately involved in the maintenance of cellular structure and function. It has also become clear that metabolic events involved in the synthesis and hydrolysis of ATP as well as for the synthesis of proteins and phospholipids are essential for cellular health...read more

Product Description: 1. Secondary Metabolism and Differentiation In addition to the primary metabolic reactions, which are similar in all living beings (formation and breakdown of nucleic acids and proteins as well as of their precursors, of most carbohy­ drates, of some carboxylic acids, etc...read more

Product Description: The understanding of physiological processes requires knowledge at different scales, ranging from physical chemistry to whole organisms. This book examines the remarkable diversity of metabolic processes involved in capillary permeation, cellular transport and reaction kinetics...read more

Product Description: Complex and unexplained phenomena tend to foster unorthodox perspectives. This publication is an example, as is a prior publication that emphasized the concept that intermediary metabolism might play a significant and determining role in hepatocyte proliferation and 1 tumorigenesis...read more

Product Description: The book covers major advances made in cellular bioenergetics, a central topic in biological and medical research. The chapters, contributed by authors representing major groups working in the field, extend from the latest advancements in X-ray crystallographic analysis of the atomic structure of energy transfer membrane proteins and analysis of their mechanism of action, to perspectives on the implication of their genetic and phenotypic defects in human diseases...read more (view table of contents, read Amazon.com's description)

Product Description: Allegory in America surveys the history of American allegorical writing from the Puritans through the period of American romanticism to postmodernism. In a series of theoretical chapters the cultural function of allegory is discussed in relation to the mythology of American exceptionalism...read more

Product Description: This book is about the chemistry of phosphate monoester hydrolysis catalyzed by enzymes called phosphatases, focusing on their chemistry at a molecular level, i.e. their structure, function, and mechanism of action. At present, six classes of phosphatase are well characterized: (i) alkaline phosphatases, (ii) purple acid phosphatases, (iii) high molecular weight acid phosphatases, (iv) low molecular weight acid phosphatases, (v) phosphotyrosine phosphatases, and (vi) serine/threonine phosphatases...read more

Product Description: This book is about enzyme organization in matrix spaces of the cell, which is a prerequisite of metabolite channelling, a process which facilitates substrate delivery in metabolic pathways. The structural, functional and regulatory consequences as well as physiological significance of these processes are reviewed on the bases of theoretical and experimental results carried out at different levels of complexity and organization...read more

Product Description: Adenine Nucleotides play a major role in cellular metabolism and functions, serving as high-potential phosphate transfer compounds in energy metabolism and as substrates and co-factors for proteins involved in signal transduction...read more

Product Description: Intracellular Calcium Regulation Editor Felix Bronner A notable development in biological research is the recent widespread interest in the role played by calcium in cellular metabolism. Calcium homeostasis has been studied intensively for many years and mechanisms by which calcium absorption, excretion and bone deposition are effected and regulated are beginning to be understood in detail...read more (view table of contents, read Amazon.com's description)