All Mrs. Pollifax wants on this spring day is the peace and quiet of her Connecticut greenhouse. Then she discovers that a young woman, Kadi Hopkirk, has been hiding in her junk closet for two days. Kadi spills out an improbable story - that since a chance meeting with a childhood friend she has been followed by persons unknown in a sinister van. She's convinced that the henchmen inside are hellbent on finding her. A little experiment on Mrs. P's part proves at least this part of the story correct.

Kadi soon confides the rest of the story - a close tie with an assassinated foreign president and an item in her possession that makes both her and our sleuth moving targets for - someone. When Mrs. P puts in a call for help to her old CIA crony Carstairs, he's wrapped up in the kidnap of a wealthy financier. Before she knows it, what began as a dash for safety and a call for help expands into an assignment that leads to hair-trigger violence in exotic places.