Tables of Contents for Bioartificial Organs II

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Chapter/Section Title

Page #

Page Count

Dedication

Acknowledgments

David Hunkeler

Introduction

xiii

David Hunkeler

Part I. Overview

Bioartificial Organs: Risks and Requirements

David Hunkeler

Part II. Novel Materials

Control of Complement Activities for Immunoisolation

Hiroo Iwata

Yoshinobu Murakami

Yoshito Ikada

Designing Biomaterials to Direct Biological Responses

Kevin E. Healy

Alireza Rezania

Ranee A. Stile

New Microcapsules Based on Oligoelectrolyte Complexation

Artur Bartkowiak

David Hunkeler

Development of Cellulose Sulfate-based Polyelectrolyte Complex Microcapsules for Medical Applications

Horst Dautzenberg

Ute Schuldt

Gerd Grasnick

Peter Karle

Petra Muller

Matthias Lohr

Mireia Pelegrin

Marc Piechaczyk

Kerstin V. Rombs

Walter H. Gunzburg

Brian Salmons

Robert M. Saller

Radiation Sterilization of a Bifunctional Cement Formulation of Hydroxilapatite-Plaster-Polymers

Dianelys Sainz Vidal

Dania Rodriguez Napoles

Gaston Fuentes Estevez

Mercedes Guerra

Williams Arcis Soriano

Eduardo Peon Aves

Jose M. Diaz Argota

Dionisio Zaldivar Silva

Part III. Encapsulation: Fundamentals and Applications

Artificial Cells, Encapsulation and Immobilization

Thomas Ming Swi Chang

Physico-Chemical and Mass Transfer Considerations in Microencapsulation

Mattheus F.A. Goosen

In Situ Electrochemical Oxygen Generation with an Immunoisolation Device

105

Haiyan Wu

Efstathios S. Avgoustiniatos

Larry Swette

Susan Bonner-Weir

Gordon C. Weir

Clark K. Colton

Conformal Coating of Small Particles and Cell Aggregates at a Liquid-Liquid Interface

126

Michael H. May

Michael V. Sefton

New Multicomponent Capsules for Immunoisolation

135

Artur Bartkowiak

Laurence Canaple

Ion Ceausoglu

Nathalie Nurdin

Andreas Renken

Lorenz Rindisbacher

Christine Wandrey

Beatrice Desvergne

David Hunkeler

Encapsulation for Somatic Gene Therapy

146

Patricia L. Chang

Review---The Use of Immunosuppressive Agents to Prevent Neutralizing Antibodies Against a Transgene Product

159

Murray A. Potter

Patricia L. Chang

Part IV. Islet Isolation, Transplantation and the Bioartificial Pancreas

Potential Application of Neonatal Porcine Islets as Treatment for Type 1 Diabetes: A Review

175

Gina R. Rayat

Ray V. Rajotte

Gregory S. Korbutt

Clinical Islet Transplantation: A Review

189

Jose Oberholzer

Frederic Triponez

Jinning Lou

Philippe Morel

Islet Cryopreservation Protocols

200

Ray V. Rajotte

Bioartificial Pancreas: Alternative Supply of Insulin Secreting Cells

208

Daobiao Zhou

Ekaterina Kintsourashivili

Salim Mamujee

Ivan Vacek

Anthony M. Sun

Transplantation of Pancreatic Islets Contained in Minimal Volume Microcapsules in Diabetic High Mammalians

219

Riccardo Calafiore

Giuseppe Basta

Giovanni Luca

Carlo Boselli

Andrea Bufalari

Antonello Bufalari

Maria Paola Cassarani

Gian Mario Giustozzi

Paolo Brunetti

Evaluation of Graft-Host Response for Various Tissue Sources and Animal Models

233

Collin J. Weber

Susan Safley

Mary Hagler

Judith Kapp

Part V. Biological Aspects

Antigen Presentation Pathways for Immunity to Islet Transplants: Relevance to Immunoisolation

255

Ronald G. Gill

Factors in Xenograft Rejection

261

Simon C. Robson

Jan Schulte Am Esch II

Fritz H. Bach

Encapsulated, Genetically Engineered Cells, Secreting Glucagon-like Peptide-1 for the Treatment of Non-Insulin-dependent Diabetes Mellitus

277

Remy Burcelin

Eric Rolland

Wanda Dolci

Stephane Germain

Veronique Carrel

Bernard Thorens

Genetically Engineered Pancreatic β-Cell Lines for Cell Therapy of Diabetes

286

Shimon Efrat

Re-engineering the Functions of a Terminally Differentiated Epithelial Cell in Vivo

294

Bruce J. Baum

Songlin Wang

Edna Cukierman

Christine Delporte

Hideaki Kagami

Yitzhak Marmary

Philip C. Fox

David J. Mooney

Kenneth M. Yamada

Reverse Engineering of Bioadhesion in Marine Mussels

301

J. Herbert Waite

Part VI. Bioartificial Liver

Overview of Extracorporeal Liver Support Systems and Clinical Results

310

Brian E. McLaughlin

Christine M. Tosone

Linda M. Custer

Claudy Mullon

Bioreactors for Hybrid Liver Support: Historical Aspects and Novel Designs

326

Benedikt Busse

Jorg C. Gerlach

Novel Bioartificial Liver Support System: Preclinical Evaluation

340

John F. Patzer II

George V. Mazariegos

Roberto Lopez

Ernesto Molmenti

David Gerber

Fridtjov Riddervold

Ajai Khanna

Wen-Yao Yin

Yong Chen

Victor L. Scott

Shushma Aggarwal

David J. Kramer

Robert A. Wagner

Yue Zhu

Melissa L. Fulmer

Geoffrey D. Block

Bruce P. Amiot

Three-dimensional in Vitro Cell Culture Leads to a Marked Upregulation of Cell Function in Human Hepatocyte Cell Lines---An Important Tool for the Development of a Bioartificial Liver Machine

353

Clare Selden

Ali Shariat

Paschal McCloskey

Tim Ryder

Eve Roberts

Humphrey Hodgson

Cultivation and Characterization of a New Immortalized Human Hepatocyte Cell Line HepZ for the Usage in an Artificial Liver Support System

364

A. Werner

S. Duvar

J. Muthing

H. Buntemeyer

U. Kahmann

H. Lunsdorf

J. Lehmann

Part VII. Skin, Bone, Cartilage and Craniofacial Issues

rhBMP-Collagen Sponges as Osteoinductive Devices: Effects of in Vitro Sponge Characteristics and Protein pI on in Vivo rhBMP Pharmacokinetics

369

H. Uludag

W. Friess

D. Williams

T. Porter

G. Timony

D. D'Augusta

C. Blake

R. Palmer

B. Biron

J. Wozney

Tissue Engineering of Bone in the Craniofacial Complex

379

Jeffrey O. Hollinger

Shelley R. Winn

Computer Controlled Bioreactor for Large-scale Production of Cultured Skin Grafts

386

J.E. Prenosil

M. Kino-Oka

A Method for Tissue Engineering of Cartilage by Cell Seeding on Bioresorbable Scaffolds

398

Ronda E. Schreiber

Noushin S. Dunkelman

Gail Naughton

Anthony Ratcliffe

Bioreactor Development for Tissue-Engineered Cartilage

405

Florence Wu

Noushin Dunkelman

Al Peterson

Twana Davisson

Rebecca De La Torre

Deepak Jain

Index of Contributors

413