Foreword

Preface

Contributors

Part I. Background Issues in Hypertension

Studies Justifying the Use of Treatment to Prevent Cardiovascular Events

Henry R. Black

Effects of Aging on Blood Pressure

Vincent DeQuattro

Effects of Race on Blood Pressure

John M. Flack

Genetics in Hypertension

Joel M. Neutel

David H. G. Smith

Sodium and Other Dietary Factors

Myron H. Weinberger

Role of Stress in Development of Hypertension

Thomas G. Pickering

Neuroendocrine Factors: Role of the Sympathetic Nervous and Renin Angiotensin Systems

Stevo Julius

Left Ventricular Hypertrophy and Diastolic Dysfunction

George A. Mansoor

William B. White

Role of the Endothelium in Hypertension

Ellis R. Levin

Part II. Diagnosis and Special Tests

Systolic, Diastolic, Mean, or Pulse Pressure: Which Is the Best Predictor of Hypertensive Cardiovascular Risk?

Stanley S. Franklin

Manual Blood Pressure Measurement---Still the Gold Standard: Why and How to Measure Blood Pressure the Old Fashioned Way

Carlene M. Grim

Clarence E. Grim

Initial Routine Tests for Diagnosis and Risk Stratification of the Patient with Hypertension: What Is Mandatory?

Tudor Vagaonescu

Robert A. Phillips

When to Suspect Secondary Hypertension

Donald G. Vidt

Evaluation of Renal Function and Proteinuria

Ira W. Reiser

Jerome G. Porush

Ambulatory Blood Pressure Monitoring

David H. G. Smith

Arterial Compliance in Hypertension

G. E. McVeigh

Li Lan Yoon

Part III. Principles of Treatment

Starting Hypertension Treatment: Setting Targets

Michael A. Weber

Choosing the First Agent

Matthew R. Weir

Managing an Inadequate Response to the First Agent: Changing Doses or Drugs, Adding Drugs

L. Michael Prisant

Rationale of Low-Dose Combination Therapy in Cardiovascular Risk Management

Joel M. Neutel

David H. G. Smith

How to Monitor Progress in Hypertensive Patients

Ehud Grossman

Problems of Treatment Compliance and Polypharmacy

Gordon S. Stokes

Philip A. Atkin

Should Treatment Differ in African-American and Caucasian Patients?

W. Dallas Hall

Measuring the Benefits of Antihypertensive Treatment

Michael A. Weber

Part IV. Major Hypertensive Drug Classes

Diuretics in Hypertension Therapy

James R. Sowers

Joel M. Neutel

Matthew R. Weir

β-Adrenergic Blocker Treatment of Hypertension: Pharmacodynamics and Guide to Patient Selection

Jon D. Blumenfeld

Calcium Antagonists

Franz H. Messerli

Jayant Dey

Zhanbin Feng

Angiotensin-Converting Enzyme Inhibitors

Irene Gavras

Haralambos Gavras

The Angiotensin II Receptor Blockers

Michael A. Weber

Selective α1 - Blockers

Joseph L. Izzo, Jr.

Centrally Acting Antihypertensive Drugs

Mark Houston

Part V. Solving Problems in Hypertension Management

The National Health and Nutrition Examination Survey III: How Are We Doing with Blood Pressure Control?

David A. Calhoun

Suzanne Oparil

Lipid Abnormalities and Hypertension

Thomas D. Giles

Diabetes and Hypertension

Kurt M. R. Sowers

James R. Sowers

Treatment of Hypertensive Patients with Chronic Renal Insufficiency

Samuel Spitalewitz

Jerome G. Porush

Treating Angina Pectoris in Hypertension

Hal L. Chadow

Joel A. Strom

Hypertension and Its Treatment in Concomitant Conditions: Degenerative Joint Disease, Depression, Alzheimer's Disease, and Parkinson's Disease

Domenic A. Sica

Cognitive Disorders and Dementia in Hypertension: Implications for Treatment

Lena Kilander

Refractory Hypertension

C. Venkata S. Ram

Hypertensive Emergencies

Dilek K. Sowers

Referring to Hypertension Experts: The Hypertension Consultant

Lawrence R. Krakoff

Index