Preface

Acknowledgments

Contributors

Analytical Issues Affecting the Clinical Performance of Cardiac Troponin Assays

Alan H.B. Wu

Prepare To Meet Your Markers: Making the Most out of Troponin I Degradation

Jason L. McDonough

Ralf Labugger

Jennifer E. Van Eyk

Functional Sensitivity of Cardiac Troponin Assays and its Implications for Risk Stratification for Patients with Acute Coronary Syndromes

Kiang-Teck J. Yeo

Kelly S. Quinn-Hall

Stephanie W. Bateman

George A. Fischer

Stacey Wieczorek

Alan H.B. Wu

Report on a Survey of Analytical and Clinical Characteristics of Commercial Cardiac Troponin Assays

Fred S. Apple

Jesse E. Adams, III

Alan H.B. Wu

Allan S. Jaffe

The Current Assessment of Qualitative and Quantitative Point-of-Care Testing of Cardiac Markers

Roland Valdes, Jr.

Saeed A. Jortani

Acute Coronary Syndromes: Pathophysiology, Clinical Presentation, and Initial Diagnostic Strategies

Jesse E. Adams, III

Vickie A. Miracle

WHO Criteria: Where Do We Go from Here?

Allan S. Jaffe

An Integrated Diagnostic Approach to the Patient with Chest Pain

Robert L. Jesse

Michael C. Kontos

The Use of Cardiac Markers for Therapeutic Decisions in Acute Coronary Syndromes

Michael P. Hudson

Britta U. Goldmann

E. Magnus Ohman

The Evaluation of Acute Coronary Syndrome in the Emergency Department: The Impact of Cardiac Biomarkers and ST-Segment Trend Monitoring

David A. Grundy

W. Brian Gibler

Cardiac Troponin T in Coronary Artery Disease: Where Do We Stand?

Evangelos Giannitsis

Britta Weidtmann

Margit Muller-Bardorff

Norbert Frey

Hugo A. Katus

Creatine Kinase: A Marker for the Early Diagnosis of Acute Myocardial Infarction

Robert Fromm

Robert Roberts

Fatty Acid Binding Protein as a Plasma Marker for the Early Assessment of Individuals with Acute Coronary Syndromes

Jan F.C. Glatz

Wim T. Hermens

Oxidized Low-Density Lipoprotein and Malondialdehyde-Modified Low-Density Lipoprotein: Markers of Coronary Artery Disease

Paul Holvoet

Frans Van de Werf

Johan Vanhaecke

Desire Collen

High-Sensitivity C-Reactive Protein: A Novel Inflammatory Marker for Predicting the Risk of Coronary Artery Disease

Paul M. Ridker

Nuclear Factor Kappa B: A Marker of Coronary Artery Disease Activity?

George K. Daniel

Richa Gupta

Jessica Gillespie

Rose Felten

Linda Cise

Kathy Sturdevant

Michael E. Ritchie

The Use of Troponins to Detect Cardiac Injury after Cardiac and Noncardiac Surgery

Jesse E. Adams, III

The Role of Cardiac Troponin Testing in Renal Disease

Fred S. Apple

The Use of Cardiac Biomarkers for the Detection of Drug-Induced Myocardial Damage

Eugene H. Herman

V.J. Ferrans

The Utility of Brain Natriuretic Peptides in Patients with Heart Failure and Coronary Artery Disease

Johannes Mair

Index