Introduction

Michael B Kastan

Control of the G(1)/S Transition

S.I.Reed

S Phase Damage Sensing Checkpoints in Mammalian Cells

J.M.Larner

H.Lee

J.L.Hamlin

Cyclins and the G(2)/M Transition

M.R.Jackman

J.N.Pines

The DNA Replication Licensing System

Pia Thommes

J.Julian Blow

Cyclin Dependent Kinase Inhibitors

J.Wade Harper

Yeast Checkpoint Controls and Relevance to Cancer

T.Weinert

The Anaphase Promoting Complex

A.M.Page

P.Hieter

Mammalian G(1) and G(2) Phase Checkpoints

P.M.O'Connor

Maintaining Genetic Stability through TP53 Mediated Checkpoint Control

G.M.Wahl

S.P.Linke

T.G.Paulson

L.-c Huang

Functions of the DNA Dependent Protein Kinase

Shengfang Jin

Satoshi Inoue

David T. Weaver

Telomerase, Checkpoints and Cancer

Calvin B. Harley

Steven W. Sherwood

The ATM Gene and Protein: Possible Roles in Genome Surveillance, Checkpoint Controls and Cellular Defence against Oxidative Stress

Galit Rotman

Yosef Shiloh

Apoptosis and Cancer Mechanisms

Huichin Pan

Chaoying Yin

Terry Van Dyke

Genetic Instability in Animal Tumorigenesis Models

Larry A Donehower

BIOGRAPHICAL NOTES

INDEX