Series Introduction

Michael A. Kaliner

Richard F. Lockey

Preface

Contributors

Part One INTRODUCTION

Introduction

Burton Zweiman

Part Two COMPONENTS IN THE ALLERGIC INFLAMMATORY RESPONSE

Mast Cells and Basophils

Lawrence B. Schwartz

Eosinophils

Douglas S. Robinson

Andrew J. Wardlaw

A. Barry Kay

Neutrophils

Burton Zweiman

Lymphocytes

Sergio Romagnani

Leukocyte-Blood Vessel Interactions

Kelly L. Davenpeck

Bruce S. Bochner

Extracellular Matrix

Clive R. Roberts

David C. Walker

R. Robert Schellenberg

The Regulation of IgE Synthesis

Donata Vercelli

Effector Roles of IgE Antibodies: Targeting Allergen to the High-Affinity IgE Receptor for FcϵRI-Dependent Signaling and Antigen Presentation

Bridget S. Wilson

Janet M. Oliver

Lipid Inflammatory Mediators: Leukotrienes, Prostaglandins, Platelet-Activating Factor

Pandora E. Christie

William R. Henderson, Jr.

Cytokines in Allergic Inflammation

Rafeul Alam

Gita Kampen

Part Three ALLERGIC INFLAMMATORY MECHANISMS IN CLINICAL DISORDERS

Mechanisms of Allergic Rhinitis

Yong-Jin Park

James N. Baraniuk

Nasal Polyps and Sinusitis

Raymond G. Slavin

Allergic Eye Disorders

Leonard Bielory

Sergio Bonini

Stefano Bonini

Asthma

Saju S. Eapen

William W. Busse

Atopic Dermatitis

Peck Y. Ong

Donald Y. M. Leung

Urticaria

Malcolm Watson Greaves

Anaphylaxis and Inflammation

Mark S. Dykewicz

Nonanaphylactic Drug Disorders

Roland Solensky

Rebecca S. Gruchalla

Vasculitis

Nabih I. Abdou

Allergic Bronchopulmonary Aspergillosis, Allergic Fungal Sinusitis, and Hypersensitivity Pneumonitis

Paul A. Greenberger

Part Four EMERGING CONCEPTS IN THE MODULATION OF ALLERGIC INFLAMMATION

Pharmacological Approaches

Pedro C. Avila

Jeffrey L. Kishiyama

Daniel C. Adelman

Synthetic and Genetically Engineered Allergen Derivatives for Specific Immunotherapy of Type I Allergy

Rudolf Valenta

Susanne Vrtala

Margit Focke-Tejkl

Anna Twardosz

Ines Swoboda

Agnes Bugajska-Schretter

Susanne Spitzauer

Dietrich Kraft

Anti-IgE Antibody Therapy

Donald MacGlashan, Jr.

Allergen Injection Immunotherapy

Eva-Maria Varga

Stephen R. Durham

DNA Immunomodulation of Asthma

Joel N. Kline

Zuhair K. Ballas

Part Five OVERALL SUMMARY/CONCLUSIONS

Mechanisms of Allergic Disease and the Implications for Therapeutic Interventions

Lawrence B. Schwartz

Index