Preface

Contributors

Novel Cytokines and Cellular Components

Thrombopoietin: Basic Biology and Clinical Effects

Kenneth Kaushansky

C. Glenn Begley

Preclinical Biology and Potential Clinical Utility of flt3 Ligand

Douglas E. Williams

Stem Cell Factor

Leo Lacerna, Jr.

Russell Basser

C. Glenn Begley

Jeffrey Crawford

George Demetri

Craig H. Moskowitz

Guido Tricot

Andrew Weaver

William P. Sheridan

John A. Glaspy

Cytokine Modulation of Hematopoietic Stem Cell Phenotype

Ahmad-Samer Al-Homsi

Peter J. Quesenberry

Homing and Self-Renewal of Hematopoietic Stem Cells

Anthony D. Ho

Michael Punzel

Stefan Fruehauf

Shiang Huang

Bernhard Palsson

Requirements for Hematopoietic Stem Cell Engraftment and Graft Engineering: Role of Facilitating Cells

Michael Neipp

Christina L. Kaufman

Marianne Bergheim

Beate G. Exner

Suzanne T. Ildstad

Ins and Outs of Hematopoietic Stem Cells: Regulation by Genes and Stromal Cells

Christa E. Muller-Sieburg

Rajeev Soni

Cell-Signaling by Adhesion Receptors in Normal and Leukemic Hematopoiesis

Catherine M. Verfaillie

Yuehua Jiang

Robert C. H. Zhao

Felipe Prosper

Ravi Bhatia

Detection of Infrequent Cells in Blood and Bone Marrow by Flow Cytometry

Leon W. M. M. Terstappen

Animal Models

Human/Sheep Hematopoietic Chimeras

Graca Almeida-Porada

Christopher D. Porada

Nam D. Tran

Joao L. Ascensao

Esmail D. Zanjani

Canine Models for Transplantation and Gene Therapy

Hans-Peter Kiem

Rainer Storb

Murine Model of In Utero Transplantation

Ewa Carrier

CD34+ Selection

CD34 Selection Using Immunomagnetic Beads

Robert A. Preti

Andrew L. Pecora

Tauseef Ahmed

Timothy J. Farley

Autologous and Allogeneic Transplantation with Blood CD34+ Cells: A Pediatric Experience

Yoshifumi Kawano

Yoichi Takaue

Tsutomu Watanabe

Yasuhiro Okamoto

Takanori Abe

Yasuhiro Kuroda

Arata Watanabe

Using Allogeneic Graft Engineering to Improve Long-Term Survival

Stephen J. Noga

Purging

Detection and Significance of Minimal Residual Disease from Solid Tumor Malignancies in Stem Cell Autografts

Amy A. Ross

Stem Cell Isolation with Immunomagnetic Beads and Tumor Cell Contamination

Gunnar Kvalheim

Anne Pharo

Harald Holte

Elisabeth Lenschow

Mengyu Wang

Bjorn Erikstein

Stein Kvaloy

John Magne Nesland

Erlend Smeland

Ex Vivo Expansion

CD34 Cell Culture: Clinical Needs and Applications

Dennis E. Van Epps

Critical Parameters Influencing the Expansion and Differentiation of Cultured Human CD34+ Cells

Jane S. Lebkowski

Lisa R. Schain

Advances in Allogeneic Transplantation

Mobilization of Peripheral Blood Stem Cells from Normal Donors

Thomas A. Lane

Ping Law

Innovative Approaches for Allogeneic Blood and Marrow Transplantation for Treatment of Hematological Malignancies: Graft Engineering and Nonmyeloablative Preparative Regimens

Richard E. Champlin

Peripheral Blood Stem Cells for Allogeneic Transplantation

Lutz Uharek

Peter Dreger

Bertram Glass

Matthias Zeis

Norbert Schmitz

Mechanisms of Cure of Acute Myeloid Leukemia with Allogeneic Transplantation

Frederick R. Appelbaum

Late Complications of Hematopoietic Stem Cell Transplantation

Emin Kansu

Keith M. Sullivan

GVHD, GVL

Prevention of Acute Graft-Versus-Host Disease by Delayed or Selected Lymphocyte Add Back

John Barrett

Dimitrios Mavroudis

Advances in Autologous Transplantation

Blood Stem Cell Versus Bone Marrow Transplantation: A Critical Appraisal

Anne Kessinger

Autologous Peripheral Blood Stem Cell Collection and Engraftment

Stefan Hohaus

Maria Teresa Voso

Simona Martin

Rainer Haas

Stem Cell Transplantation for Hodgkin's Disease

Ram Kancherla

Tauseef Ahmed

Stem Cell Transplantation for Multiple Myeloma-10 Years Later

David S. Siegel

Seah H. Lim

Guido Tricot

K. R. Desikan

A. Fassas

Jayesh Mehta

Seema Singhal

Elias Anaissie

Sundar Jagannath

Barthel Barlogie

High-Dose Therapy for Primary and Metastatic Breast Cancer

Gary Spitzer

Kenneth Meehan

Douglas Adkins

Genetic and Immune Therapy

Gene Therapy Using Hematopoietic Stem Cells

Donald B. Kohn

Gay M. Crooks

Jan A. Nolta

Gene Therapy for Human Immunodeficiency Virus Infection Using Stem Cell Transplantation

Alain Gervaix

Flossie Wong-Staal

Autografting Followed by Low-Intensity Conditioning Regimen for Allografting

Angelo M. Carella

Development of Retroviral Vectors that Target Hematopoietic Stem Cells

Chris A. Benedict

Yi Zhao

Nori Kasahara

Paula M. Cannon

W. French Anderson

Index