Contributors

Series Preface

Roger R. Markwald

Foreword

Roger R. Markwald

Preface

PART I: ASSEMBLY OF MYOFIBRILLAR PROTEINS IN STRIATED MUSCLE

Myofibrillogenesis in Cardiac Muscle

Joseph W. Sanger

Jean M. Sanger

Dynamics of Contractile Proteins Constituting Myofibrils in Living Muscle Cells

Yutaka Shimada

Tin Moe Nwe

Fukuko Hasebe-Kishi

Homare Suzuki

Emergence of the First Myofibrils and Targeting Mechanisms Directing Sarcomere Assembly in Developing Cardiomyocytes

Elisabeth Ehler

Jean-Claude Perriard

Tropomodulin: An Important Player in Cardiac Myofibrillogenesis

Catherine McLellan

Carol C. Gregorio

PART II: MAINTENANCE AND MANIPULATION OF MYOFIBRILLAR ORGANIZATION

Maintaining the Fully Differentiated Cardiac Sarcomere

Daniel E. Michele

Joseph M. Metzger

Manipulation of Myofibrillogenesis in Whole Hearts

Robert W. Zajdel

Matthew D. McLean

Christopher R. Denz

Syamalima Dube

Larry F. Lemanski

Dipak K. Dube

PART III: REGULATION OF EXPRESSION OF MYOFIBRILLAR PROTEINS

Molecular Regulation of Cardiac Myofibrillogenesis: Roles of Serum Response Factor, Nkx2-5, and GATA-4

Robert J. Schwartz

Jorge Sepulveda

Narasimhaswamy S. Belaguli

Regulation and Organization of Human Troponin Genes

Paul J.R. Barton

Kimberley A. Dellow

Pankaj K. Bhavsar

Martin E. Cullen

Antony J. Mullen

Nigel J. Brand

Signal Transduction in Myofibrillogenesis, Cell Growth, and Hypertrophy

M.A.Q. Siddiqui

Michael Wagner

Eduardo Mascareno

Saiyid Shafiq

Cytoskeletal Gene Expression in the Developing Cardiac Conduction System

Robert E. Welikson

Takashi Mikawa

PART IV: HEART DEVELOPMENT AND MYOFIBRILLAR ORGANIZATION

Onset of a Cardiac Phenotype in the Early Embryo

Leonard M. Eisenberg

Carol A. Eisenberg

Cellular, Molecular, and Developmental Studies on Heart Development in Normal and Cardiac Mutant Axolotls, Ambystoma mexicanum

Larry F. Lemanski

Xupei Huang

Robert W. Zajdel

Sharon L. Lemanski

Chi Zhang

Fanyin Meng

Dalton Foster

Qing Li

Dipak K. Dube

PART V: CARDIOMYOPATHY AND MYOFIBRILLAR ORGANIZATION

The Function of Normal and Familial Hypertrophic Cardiomyopathy-Associated Tropomyosin

Rethinasamy Prabhakar

Kathy Pieples

Ganapathy Jagatheesan

Stephanie Burge

David F. Wieczorek

Cardiomyopathies and Myofibril Abnormalities

Jeffrey A. Towbin

Neil E. Bowles

Index