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Tables of Contents for Foye's Principles of Medicinal Chemistry
Chapter/Section Title
Page #
Page Count
Introduction Origins of Medicinal Chemistry
William O. Foye
1
10
Part I Principles of Drug Discovery
11
234
Overview Drug Design and Development: A Perspective
Michael Williams
12
12
Natural Products
Alice M. Clark
24
13
Drug Design and Relationship of Functional Groups to Pharmacologic Activity
James J. Knittel and Robin M. Zavod
37
31
Molecular Modeling and Drug Design
Eric Billings
68
18
Receptors and Drug Action
Timothy J. Maher and David A. Johnson
86
14
Drug Design Through Enzyme Inhibition
Stephen G. Kerr
100
14
Peptide and Protein Drugs
Michael Mokotoff
114
29
Physicochemical and Biopharmaceutical Properties of Drug Substances and Pharmacokinetics
Sunil Jambhekar
143
31
Drug Metabolism
David A. Williams
174
60
U.S. Drug Regulation: An Overview
Douglas J. Pisano
234
11
Part II Pharmacodynamic Agents
245
19
Overview Drug Receptors: A Perspective
David J. Triggle
246
18
Section 1 Drugs Affecting Neurotransmission
264
93
Drugs Affecting Cholinergic Neurotransmission
Danny L. Lattin and E. Kim Fifer
264
28
Drugs Affecting Adrenergic Neurotransmission
Robert Griffith
292
23
Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission
Richard A. Glennon and Malgorzata Dukat
315
23
Local Anesthetics
Matthias C. Lu
338
19
Section 2 Drugs Affecting Central Nervous System
357
140
Volatile Anesthetics
Timothy J. Maher
357
13
Hypnotics
William Soine
370
14
Antiseizure Drugs
Barbara W. Leduc
384
24
Psychotherapeutic Drugs: Antipsychotic and Anxiolytic Agents
Raymond G. Booth and John L. Neumeyer
408
26
Hallucinogens, Stimulants, and Related Drugs of Abuse
Richard A. Glennon
434
19
Opioid Analgesics
David S. Fries
453
27
Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents
Raymond G. Booth and John L. Neumeyer
480
17
Section 3 Drugs Affecting the Cardiovascular System
497
132
Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs
Ahmed S. Mehanna
497
21
Diuretics
Gary O. Rankin
518
15
Angiotensin Converting Enzyme Inhibitors, Antagonists and Calcium Blockers
Marc W. Harrold
533
29
Central and Peripheral Sympatholytics and Vasodilators
David A. Williams
562
18
Antihyperlipoproteinemics and Inhibitors of Cholesterol Biosynthesis
Marc W. Harrold
580
24
Antithrombotics, Thrombolytics, Coagulants and Plasma Extenders
Robert B. Palmer
604
25
Section 4 Drugs Affecting the Hormonal Systems
629
122
Insulin and Oral Hypoglycemic Drugs
Robert A. Wiley
629
24
Adrenocorticoids
Duane D. Miller Robert W. Brueggemeier and James T. Dalton
653
32
Estrogen, Progestins and Androgens
Robert W. Brueggemeier Duane D. Miller and James T. Dalton
685
33
Thyroid Function and Thyroid Drugs
Ali R. Banijamali
718
21
Calcium Homeostasis
Robin M. Zavod
739
12
Section 5 Drugs Affecting the Immune Systems
751
68
Nonsteroidal Anti-Inflammatory Agents
Ronald F. Borne
751
43
Antihistamines and Related Antiallergic and Antiulcer Agents
Wendel L. Nelson
794
25
Section 6 Chemotherapeutic Agents
819
162
Antibiotics and Antimicrobial Agents
Lester A. Mitscher
819
48
Antiparasitic Agents
Thomas L. Lemke
867
24
Antifungal Drugs
Robert Griffith and Timothy Tracy
891
13
Antimycobacterial Agents
Thomas L. Lemke
904
20
Cancer and Cancer Chemotherapy
Patrick S. Callery and Peter M. Gannett
924
28
Antiviral Agents and Protease Inhibitors
Manohar L. Sethi
952
29
Part III Recent Advances in Drug Discovery
981
89
Pharmaceutical Biotechnology
Robert D. Sindelar
982
34
Gene Therapy
Ronald E. Reid
1016
36
Antisense Therapeutic Agents
Marilyn K. Speedie
1052
7
Selective Estrogen Receptor Modulators
V. Craig Jordan
1059
11
Appendices pKa Values for Some Drugs and Miscellaneous Organic Acids and Bases pH Values for Tissue Fluids
David A. Williams
1070
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