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Tables of Contents for Foye's Principles of Medicinal Chemistry
Chapter/Section Title
Page #
Page Count
Introduction Origins of Medicinal Chemistry
1
10
Part I Principles of Drug Discovery
11
234
Overview Drug Design and Development: A Perspective
12
12
Natural Products
24
13
Drug Design and Relationship of Functional Groups to Pharmacologic Activity
37
31
Molecular Modeling and Drug Design
68
18
Receptors and Drug Action
86
14
Drug Design Through Enzyme Inhibition
100
14
Peptide and Protein Drugs
114
29
Physicochemical and Biopharmaceutical Properties of Drug Substances and Pharmacokinetics
143
31
Drug Metabolism
174
60
U.S. Drug Regulation: An Overview
234
11
Part II Pharmacodynamic Agents
245
19
Overview Drug Receptors: A Perspective
246
18
Section 1 Drugs Affecting Neurotransmission
264
93
Drugs Affecting Cholinergic Neurotransmission
264
28
Drugs Affecting Adrenergic Neurotransmission
292
23
Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission
315
23
Local Anesthetics
338
19
Section 2 Drugs Affecting Central Nervous System
357
140
Volatile Anesthetics
357
13
Hypnotics
370
14
Antiseizure Drugs
384
24
Psychotherapeutic Drugs: Antipsychotic and Anxiolytic Agents
408
26
Hallucinogens, Stimulants, and Related Drugs of Abuse
434
19
Opioid Analgesics
453
27
Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents
480
17
Section 3 Drugs Affecting the Cardiovascular System
497
132
Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs
497
21
Diuretics
518
15
Angiotensin Converting Enzyme Inhibitors, Antagonists and Calcium Blockers
533
29
Central and Peripheral Sympatholytics and Vasodilators
562
18
Antihyperlipoproteinemics and Inhibitors of Cholesterol Biosynthesis
580
24
Antithrombotics, Thrombolytics, Coagulants and Plasma Extenders
604
25
Section 4 Drugs Affecting the Hormonal Systems
629
122
Insulin and Oral Hypoglycemic Drugs
629
24
Adrenocorticoids
653
32
Estrogen, Progestins and Androgens
685
33
Thyroid Function and Thyroid Drugs
718
21
Calcium Homeostasis
739
12
Section 5 Drugs Affecting the Immune Systems
751
68
Nonsteroidal Anti-Inflammatory Agents
751
43
Antihistamines and Related Antiallergic and Antiulcer Agents
794
25
Section 6 Chemotherapeutic Agents
819
162
Antibiotics and Antimicrobial Agents
819
48
Antiparasitic Agents
867
24
Antifungal Drugs
891
13
Antimycobacterial Agents
904
20
Cancer and Cancer Chemotherapy
924
28
Antiviral Agents and Protease Inhibitors
952
29
Part III Recent Advances in Drug Discovery
981
89
Pharmaceutical Biotechnology
982
34
Gene Therapy
1016
36
Antisense Therapeutic Agents
1052
7
Selective Estrogen Receptor Modulators
1059
11
Appendices pKa Values for Some Drugs and Miscellaneous Organic Acids and Bases pH Values for Tissue Fluids
1070