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Tables of Contents for Histopathology
Chapter/Section Title
Page #
Page Count
CHAPTER 1 CELL PATHOLOGY
1
25
Diagram
1
1.1 Response of the cell to physiologic and pathologic stimuli
1
2
1.2 Reaction of the cell to injury
3
3
1.3 Cell swelling, vacuolization, and cytoplasmic storage
6
6
1.4 Adaptive changes induced by cell injury
12
4
1.5 Metaplasia
16
2
1.6 Cell death
18
Plate
6
1.1 Vacuolar change
6
1.2 Genetic storage diseases
8
1.3 Cytoplasmic storage
10
1.4 Cellular adaptations
12
1.5 Cellular adaptations in the breast
14
1.6 Metaplasia
16
1.7 Cell death
18
1.8 Necrosis
20
CHAPTER 2 INFLAMMATION AND REPAIR
26
13
Diagram
26
2.1 Inflammatory cells
26
2
2.2 Schematic presentation of acute inflammation
28
4
2.3 Granuloma
32
4
2.4 Granulation tissue
36
Plate
26
2.1 Inflammatory cells--electron microscopy
26
2.2 Acute inflammation
28
2.3 Chronic inflammation
30
2.4 Chronic inflammation
32
2.5 Histologic features of various macroscopically distinct forms of inflammation
34
2.6 Repair and healing
36
CHAPTER 3 CIRCULATORY DISTURBANCES
39
25
Diagram
39
3.1 Circulatory disturbances
39
3
3.2 Clinically important forms of edema
42
2
3.3 Major clinically important forms of hemorrhage
44
4
3.4 Thrombosis
48
6
3.5 Pathogenesis of shock
54
Plate
42
3.1 Edema
42
3.2 Hemorrhage
44
3.3 Hyperemia and congestion
46
3.4 Thrombosis
48
3.5 Embolism
50
3.6 Infarct
52
3.7 Shock
54
CHAPTER 4 NEOPLASIA
64
28
Diagram
64
4.1 Cytological differences between normal and neoplastic cells
64
4
4.2 Grading of adenocarcinomas
68
2
4.3 Epithelial tumors of epidermis and mucosal surfaces
70
4
4.4 Adenocarcinoma
74
8
4.5 Histogenesis of teratomas
82
4
4.6 Principles of immunohistochemistry
86
Plate
64
4.1 Morphology of tumor cells
64
4.2 Cytology of neoplasia
66
4.3 Grading of tumors
68
4.4 Benign epithelial tumors
70
4.5 Malignant epithelial tumors
72
4.6 Malignant epithelial tumors
74
4.7 Benign mesenchymal tumors
76
4.8 Malignant mesenchymal tumors
78
4.9 Mixed tumors
80
4.10 Embryonal tumors
82
4.11 Other tumors
84
4.12 Special techniques--immunohistochemistry
86
4.13 Electron microscopy
88
CHAPTER 5 CARDIOVASCULAR SYSTEM
92
32
Diagram
92
5.1 Normal cardiovascular system
92
6
5.2 Pathogenesis of atherosclerosis
98
2
5.3 Myocardial infarct
100
1
5.4 Temporal sequence in the appearance of cells infiltrating a myocardial infarct
100
2
5.5 Rheumatic fever
102
2
5.6 Various forms of endocarditis
104
4
5.7 Cardiomyopathy
108
6
5.8 Diseases involving the aorta
114
Plate
98
5.1 Atherosclerosis
98
5.2 Coronary atherosclerosis and myocardial infarcts
100
5.3 Rheumatic carditis
102
5.4 Endocarditis
104
5.5 Myocarditis
106
5.6 Cardiomyopathy
108
5.7 Pericarditis
110
5.8 Neoplasms of the cardiovascular system
112
5.9 Diseases of the aorta and its major branches
114
5.10 Vascular changes caused by hypertension
116
5.11 Vasculitis
118
5.12 Vasculitis
120
CHAPTER 6 RESPIRATORY SYSTEM
124
28
Diagram
124
6.1 Normal respiratory system
124
6
6.2 Respiratory distress syndrome
130
2
6.3 Bacterial pneumonia
132
2
6.4 Viral pneumonia
134
2
6.5 Pulmonary tuberculosis
136
2
6.6 Chronic pneumonia
138
2
6.7 Immunological lung injury
140
2
6.8 Pneumoconioses
142
2
6.9 Chronic bronchitis
144
2
6.10 Emphysema
146
2
6.11 Lung cancer
148
Plate
130
6.1 Alveolar damage and atelectasis
130
6.2 Bacterial pneumonia
132
6.3 Viral and parasitic pneumonia
134
6.4 Tuberculosis and fungal pneumonia
136
6.5 Chronic pneumonia
138
6.6 Immune-mediated lung disease
140
6.7 Chronic interstitial pneumonia
142
6.8 Chronic obstructive pulmonary disease
144
6.9 Neoplasms of the lung
146
6.10 Neoplasms of the lung and pleura
148
CHAPTER 7 HEMATOPOIETIC SYSTEM
152
28
Diagram
152
7.1 Normal blood cells in circulation
152
1
7.2 Hematopoietic and lymphoid organs--thymus, lymph node, spleen, bone marrow
152
6
7.3 Morphology of RBCs in various forms of anemia
158
2
7.4 Morphology of RBCs in various forms of anemia
160
2
7.5 Bone marrow in anemia
162
4
7.6 FAB classification of acute leukemias
166
6
7.7 Cells of malignant lymphomas
172
2
7.8 Histopathology of Hodgkin disease
174
Plate
158
7.1 Anemia
158
7.2 Anemia
160
7.3 Bone marrow changes in anemia
162
7.4 Consequences and complications of anemia
164
7.5 Acute leukemias
166
7.6 Chronic leukemias
166
7.7 Tissue infiltrates in leukemia
170
7.8 Malignant lymphoma
172
7.9 Hodkin disease (HD)
174
7.10 Plasma cell neoplasia
176
CHAPTER 8 DIGESTIVE SYSTEM
180
32
Diagram
180
8.1 Normal digestive system
180
6
8.2 Most common infections of the upper digestive tract
186
4
8.3 Gastritis and peptic ulcer
190
2
8.4 Peptic ulcer
192
2
8.5 Gastric neoplasms
194
2
8.6 Small intenstinal lesions associated with malabsorption
196
4
8.7 Circulatory disturbances of the intestine
200
2
8.8 Appendicitis
202
2
8.9 Non-neoplastic intestinal polyps
204
2
8.10 Neoplastic polyps
206
Plate
186
8.1 Inflammation of the upper digestive system
186
8.2 Neoplasms of the upper digestive system
188
8.3 Gastritis
190
8.4 Peptic ulcer
192
8.5 Tumors of the stomach
194
8.6 Small intestinal lesions associated with malabsorption
196
8.7 Inflammatory bowel disease
198
8.8 Circulatory disorders and diverticulosis
200
8.9 Intestinal infections
202
8.10 Non-neoplastic polyps
204
8.11 Neoplastic polyps
206
8.12 Malignant neoplasms
208
CHAPTER 9 HEPATOBILIARY SYSTEM
212
31
Diagram
212
9.1 Normal hepatobiliary system
212
8
9.2 Biliary obstruction
220
6
9.3 Viral hepatitis
226
Plate
220
9.1 Obstructive jaundice
220
9.2 Metabolic disorders
222
9.3 Alcohol-induced liver changes
224
9.4 Acute viral hepatitis
226
9.5 Massive hepatic necrosis
228
9.6 Chronic hepatitis
230
9.7 Bacterial and parasitic hepatitis
232
9.8 Immunologic liver diseases
234
9.9 Cirrhosis
236
9.10 Liver tumors
238
9.11 Gallbladder diseases
240
CHAPTER 10 PANCREAS
243
15
Diagram
243
10.1 Normal pancreas
243
5
10.2 Acute pancreatic necrosis
248
1
Plate
248
10.1 Acute pancreatitis
248
10.2 Cystic fibrosis and meconium peritonitis
250
10.3 Pancreatic neoplasms
252
10.4 Diabetes mellitus
254
CHAPTER 11 URINARY SYSTEM
258
40
Diagram
258
11.1 Normal urinary tract
258
1
11.2 Normal glomerulus
259
9
11.3 Glomerular changes in nephrotic syndrome
268
4
11.4 Glomerular changes in nephritic syndrome
272
6
11.5 Crescentic glomerulonephritis
278
6
11.6 Developmental kidney diseases
284
10
11.7 Urinary bladder cancer
294
Plate
268
11.1 Lipoid nephrosis and focal segmental sclerosis
268
11.2 Membranous nephropathy
270
11.3 Poststreptococcal glomerulonephritis
272
11.4 Lupus nephritis
274
11.5 Membranoproliferative glomerulonephritis
276
11.6 Crescentic glomerulonephritis
278
11.7 IgA nephropathy, chronic glomerulonephritis
280
11.8 Vascular diseases
282
11.9 Developmental kidney diseases
284
11.10 Tubulointerstitial nephritis and tubular necrosis
286
11.11 Pyelonephritis
288
11.12 Renal tumors
290
11.13 Cystitis
292
11.14 Urinary bladder tumors
294
CHAPTER 12 MALE REPRODUCTIVE SYSTEM
298
21
Diagram
298
12.1 Normal male reproductive system
298
8
12.2 Epididymo-orchitis
306
2
12.3 Histogenesis of testicular germ cell tumors
308
6
12.4 Prostate
314
Plate
304
12.1 Developmental and genetic disorders
304
12.2 Infections
306
12.3 Carcinoma in situ and seminoma
308
12.4 Nonseminomatous germ cell tumors
310
12.5 Sex cord tumors and metastases
312
12.6 Prostatic diseases
314
12.7 Diseases of penis
316
CHAPTER 13 FEMALE GENITAL SYSTEM
319
32
Diagram
319
13.1 Normal female reproductive system
319
7
13.2 Infectious lesions of the female reproductive system
326
6
13.3 Carcinoma of the cervix
332
6
13.4 Ovarian neoplasms
338
2
13.5 Ovarian tumors of surface ("germinal") epithelium
340
1
13.6 Serous tumor
340
4
13.7 Germ cell tumors
344
2
13.8 Sex cord cell tumors
346
Plate
326
13.1 Vulvovaginitis
326
13.2 Inflammation of uterus and fallopian tubes
328
13.3 Vulvar dystrophy and carcinoma
330
13.4 Cervical neoplasia
332
13.5 Endometrial hormonal changes
334
13.6 Neoplasms of the uterus
336
13.7 Ovarian cysts
338
13.8 Ovarian neoplasms of surface epithelium
340
13.9 Ovarian neoplasms of surface epithelium
342
13.10 Germ cell tumors
344
13.11 Sex cord cell tumors, stromal cells and metastases
346
13.12 Pathology of pregnancy
348
CHAPTER 14 BREAST
351
19
Diagram
351
14.1 Normal breast
351
7
14.2 Fibrocystic change
358
4
14.3 Carcinoma of breast
362
Plate
356
14.1 Non-neoplastic lesions
356
14.2 Fibrocystic change
358
14.3 Gynecomastia and benign tumors
360
14.4 Intraductal carcinomas
362
14.5 Infiltrating duct carcinoma
364
14.6 Variants of breast carcinoma
366
CHAPTER 15 ENDOCRINE GLANDS
370
27
Diagram
370
15.1 Normal endocrine glands
370
12
15.2 Thyroiditis
382
2
15.3 Thyroid tumors
384
2
15.4 Parathyroid diseases
386
2
15.5 Adrenal cortical diseases
388
4
15.6 Embryogenesis and tumors of adrenal medulla
392
Plate
376
15.1 Pituitary adenoma
376
15.2 Diseases causing hypopituitarism
378
15.3 Non-neoplastic thyroid diseases
380
15.4 Thyroiditis
382
15.5 Thyroid tumors
384
15.6 Parathyroid lesions
386
15.7 Adrenal lesions
388
15.8 Adrenal cortical hyperfunction
390
15.9 Adrenal medulla
392
CHAPTER 16 SKIN
397
25
Diagram
397
16.1 Normal skin
397
7
16.2 Principal skin lesions
404
4
16.3 Infectious diseases (viral)
408
2
16.4 Infectious diseases (bacterial and fungal)
410
2
16.5 Immune diseases
412
2
16.6 Tumors of epithelial cells
414
2
16.7 Pigmented lesions
416
Plate
404
16.1 Idiopathic skin diseases
404
16.2 Lesions caused by exogenous physical injury
406
16.3 Infectious diseases (viral)
408
16.4 Infectious diseases (bacterial and fungal)
410
16.5 Immunological diseases
412
16.6 Neoplasms (epithelial)
414
16.7 Pigmented lesions
416
16.8 Dermal tumors
418
CHAPTER 17 BONES AND JOINTS
422
26
Diagram
422
17.1 Anatomy and histology of a typical long bone
422
6
17.2 Developmental disorders of the bone
428
2
17.3 Metabolic bone diseases
430
1
17.4 Rickets
430
2
17.5 Osteitis fibrosa caused by hyperparathyroidism
432
2
17.6 Healing of fracture
434
4
17.7 Bone tumors
438
2
17.8 Osteoarthritis
440
2
17.9 Rheumatoid arthritis
442
Plate
428
17.1 Developmental disorders
428
17.2 Metabolic disorders
430
17.3 Metabolic disorders
432
17.4 Osteomyelitis and fractures
434
17.5 Benign bone tumors
436
17.6 Malignant bone tumors
438
17.7 Osteoarthritis
440
17.8 Rheumatoid arthritis
442
17.9 Other joint diseases
444
CHAPTER 18 SKELETAL MUSCLES
448
12
Diagram
448
18.1 Normal skeletal muscle
448
2
18.2 Denervation of muscle due to nerve injury with subsequent reinnervation
450
2
18.3 Myopathic pattern of muscle injury
452
Plate
450
18.1 Neurogenic atrophy of the muscles
450
18.2 Muscular dystrophy
452
18.3 Myopathy
454
18.4 Myositis
456
CHAPTER 19 NERVOUS SYSTEM
460
31
Diagram
460
19.1 Components of the nervous system
460
10
19.2 Important infections of the CNS
470
6
19.3 Multiple sclerosis
476
4
19.4 Alzheimer disease
480
2
19.5 Neurodegenerative, nutritional, and toxic disorders
482
2
19.6 Most common histological features of intracranial tumors
484
Plate
466
19.1 Reaction of neurons
466
19.2 Reaction of glia cells to injury
468
19.3 Infectious diseases--meningitis
470
19.4 Infectious diseases--encephalitis
472
19.5 Infectious diseases--AIDS
474
19.6 Demyelinating diseases
476
19.7 Cerebrovascular diseases
478
19.8 Alzheimer disease
480
19.9 Nutritional deficiencies and toxic diseases
482
19.10 Neoplasms--astrocytic tumors
484
19.11 Neoplasms--astrocytic tumors
486
19.12 Meningiomas, nerve sheath tumors, and mesenchymal tumors
488
Index
491