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Tables of Contents for Therapeutic Immunology
Chapter/Section Title
Page #
Page Count
Contributors
ix
 
Preface
xv
 
PART I: INTRODUCTION
1
28
Adaptive Immunity
3
15
Emil R. Unanue
Innate Immunity and Instruction of the Adaptive Immune Response
18
11
Douglas T. Fearon
PART II: DRUGS
29
148
Antimetabolites and Radiomimetics
Cyclophosphamide
31
20
Alfred D. Steinberg
The Purine Antagonists: Azathioprine and Mycophenolate Mofetil
51
14
Nina E. Tolkoff-Rubin
Robert H. Rubin
Methotrexate
65
16
Michael E. Weinblatt
Immunosupression and Immunophilin Binding Agents: Current Research and Clinical Application
81
22
Shairaz Baksh
Jeff Friedman
Steven J. Burakoff
Barbara E. Bierer
Corticosteroids
Glucocorticoid Action
103
14
Jeffrey N. Miner
Myles Brown
Anti-Inflammatory Agents
Cyclooxygenase Inhibitors
117
15
William L. Smith
David L. DeWitt
Antileukotrienes (Leukotriene Modifiers) in the Treatment of Asthma
132
8
Jeffrey M. Drazen
Phosphodiesterase Inhibitors
140
10
Nicky Cooper
Mamidipudi Thirumala Krishna
Robert Gristwood
Stephen Holgate
Tryptase Inhibitors
150
9
Andrew F. Walls
5-Aminosalicylic Acid (Mesalamine) and Sulfasalazine
159
9
Richard P. MacDermott
Antihistamines (H1-Receptor Antagonists)
168
9
F. Estelle
R. Simons
PART III: BIOLOGIC AGENTS
177
280
Cytokines
Hematopoietic Growth Factors
179
22
Colin A. Sieff
Cytokines Regulating Immune Inflammation: Interleukin-4, Interleukin-10, and Interleukin-12
201
19
Richard N. Mitchell
Abul K. Abbas
The Interferons: Basic Biology and Therapeutic Potential
220
20
Vijay Shankaran
Robert D. Schreiber
Interleukin-21 Immunostimulation
240
11
Kendall A. Smith
A Soluble TNF Receptor-Fc Fusion Protein (Etanercept) in the Treatment of Inflammatory Diseases
251
13
Michael B. Widmer
Leslie Garrison
Kendall M. Mohler
Macromolecules
Intravenous Immunoglobulin Therapy
264
23
Francisco A. Bonilla
Raif S. Geha
Therapeutic Inhibition of Complement Activation with Emphasis on Drugs in Clinical Trials
287
15
Lloyd B. Klickstein
Francis D. Moore, Jr.
John P. Atkinson
Treatment of Angioedema Resulting from C1-Inhibitor Deficiency
302
11
A. Thomas Waytes
Fred S. Rosen
Antibody-Based Therapy
Inhibitors of Tumor Necrosis Factor
313
14
Arthur F. Kavanaugh
Peter E. Lipsky
Targeting the IL-2 Receptor with Antibodies or Chimeric Toxins
327
5
Terry B. Strom
Monoclonal Antibodies to CD3
332
10
Lucienne Chatenoud
Anti-IgE: Immunotherapy for Allergic Diseases
342
10
Donald MacGlashan, Jr.
Immunotherapy of Allergic Disease
Specific and Nonspecific Immunotherapy for Asthma and Allergic Diseases
352
19
M. Larche
A.B. Kay
Treatment of Allergy to Insect Stings
371
12
Martin D. Valentine
Chimeric Protein
The CD28 T-Cell Costimulatory Pathway: Pharmacologic Inhibition and Augmentation
383
18
Carl H. June
Jeffrey A. Ledbetter
Vaccines and Peptide Therapy
Bacterial Vaccines
401
12
Hilde-Kari Guttormsen
Dennis L. Kasper
Viral Vaccines
413
17
Ronald W. Ellis
DNA Vaccines
430
11
Harriet L. Robinson
Blockade of the CD40L/CD40 Pathway
441
16
Leonard Chess
PART IV: MANEUVERS
457
180
Transplantation
Renal Transplantation
459
10
Manikkam Suthanthiran
Terry B. Strom
Pancreas Transplantation
469
5
Michael E. Shapiro
Cardiac Transplantation
474
8
Abdallah G. Kfoury
David O. Taylor
Dale G. Renlund
Lung Transplantation
482
14
Steven J. Mentzer
Scott J. Swanson
Hemopoietic Stem Cell Transplantation
496
22
Voravit Ratanatharathorn
James L.M. Ferrara
Cell Transplantation
518
10
Luca Inverardi
Alberto Pugliese
Camillo Ricordi
Liver Transplantation
528
7
Roberto Gedaly
James J. Pomposelli
Roger L. Jenkins
Xenotransplantation
535
15
Tomasz Sablinski
David K.C. Cooper
David H. Sachs
Cellular Therapy
Cellular Therapy
550
24
Philip D. Greenberg
Stanley R. Riddell
Genetically Engineered Cancer Vaccines
574
6
Glenn Dranoff
Gene Therapy
Gene Therapy for Inherited Immunodeficiencies
580
17
Fabio Candotti
R. Michael Blaese
Additional Interventions
Plasmapheresis and Immunoadsorption
597
15
Sian Griffin
C. Martin Lockwood
Charles D. Pusey
Drug Therapy for HIV Infection
Drug Therapy for HIV Infection
612
25
John P. Doweiko
Jerome E. Groopman
Index
637