List of contributors

Preface

Acknowledgements

I. Circuitry for cognition and emotion

The prefrontal cortex and the integration of sensory, limbic and autonomic information

H. J. Groenewegen

H. B. M. Uylings

Neurobiological mechanisms of emotionally influenced, long-term memory

L. Cahill

Hypothalamic connections with the cerebral cortex

C. B. Saper

Functional neuroanatomy of the prefrontal cortex: autonomic interactions

C. G. Van Eden

R. M. Buijs

II. Attention and decision making

Functional anatomy of arousal and attention systems in the human brain

T. Paus

Attentional processes and learning and memory in rats: the prefrontal cortex and hippocampus compared

L. M. Broersen

Limitations in information processing in the human brain: neuroimaging of dual task performance and working memory tasks

T. Klingberg

Role of the prefrontal cortex of the rat in learning and decision making: effects of transient inactivation

J. P. C. De Bruin

M. G. P. Feenstra

L. M. Broersen

M. Van Leeuwen

C. Arens

S. De Vries

R. N. J. M. A. Joosten

III. Stress and reward systems in cognition

The integration of stress by the hypothalamus, amygdala and prefrontal cortex: balance between the autonomic nervous system and the neuroendocrine system

R. M. Buijs

C. G. Van Eden

Dopamine and noradrenaline release in the prefrontal cortex in relation to unconditioned and conditioned stress and reward

M. G. P. Feenstra

Locus coeruleus and regulation of behavioral flexibility and attention

G. Aston-Jones

J. Rajkowski

J. Cohen

Stress impairs prefrontal cortical function in rats and monkeys: role of dopamine D1 and norepinephrine α-1 receptor mechanisms

A. F. T. Arnsten

Involvement of basal ganglia and orbitofrontal cortex in goal-directed behavior

J. R. Hollerman

L. Tremblay

W. Schultz

Reward-dependent learning in neuronal networks for planning and decision making

S. Dehaene

J. -P. Changeux

The glutamate hypothesis of reinforcement learning

C. M. A. Pennartz

B. L. McNaughton

A. B. Mulder

Interactions between medial prefrontal cortex and meso-limbic components of brain reward circuitry

R. A. Wise

Limbic cortical-ventral striatal systems underlying appetitive conditioning

J. A. Parkinson

R. N. Cardinal

B. J. Everitt

Plasticity of neuronal firing in deep layers of the medial prefrontal cortex in rats engaged in operant conditioning

A. B. Mulder

R. Nordquist

O. Orgut

C. M. A. Pennartz

Activity patterns in mesolimbic regions in rats during operant tasks for reward

D. J. Woodward

J. -Y. Chang

P. Janak

A. Azarov

K. Anstrom

IV. Mental disorders

Reward deficiency syndrome: genetic aspects of behavioral disorders

D. E. Comings

K. Blum

Evidence of fronto-thalamic involvement in schizophrenia

M. M. Sitskoorn

M. C. M. Appels

H. E. Hulshoff Pol

R. S. Kahn

The importance of a human 3D database and atlas for studies of prefrontal and thalamic functions

H. B. M. Uylings

E. Sanz Arigita

K. de Vos

W. J. A. J. Smeets

C. W. Pool

K. Amunts

G. Rajkowska

K. Zilles

Interaction of prefrontal cortical and hypothalamic systems in the pathogenesis of depression

D. F. Swaab

E. Fliers

W. J. G. Hoogendijk

D. J. Veltman

J. N. Zhou

Histopathology of the prefrontal cortex in major depression: what does it tell us about dysfunctional monoaminergic circuits?

G. Rajkowska

Functional anatomical abnormalities in limbic and prefrontal cortical structures in major depression

W. C. Drevets

Role for dopamine in the behavioral functions of the prefrontal corticostriatal system: implications for mental disorders and psychotropic drug action

J. D. Jentsch

R. H. Roth

J. R. Taylor

Section V. The integrative role of PFC in cognition, emotion and autonomic responses

Eighth C. U. Ariens Kappers lecture1

The fabric of the mind: a neurobiological perspective

A. R. Damasio

From arousal to cognition: the integrative position of the prefrontal cortex

T. W. Robbins

Subject Index