Series Preface

Preface

Contributors

Part I Epidemiology/Molecular Biology

Molecular Epidemiology

Donghui Li

The Molecular Biology of Pancreatic Cancer

Marina E. Jean

Andrew M. Lowy

Paul J. Chiao

Douglas B. Evans

Molecular Markers as a Tool for the Early Diagnosis of Pancreatic Cancer

James R. Howe

Cell Signaling Pathways in Pancreatic Cancer

Jason B. Fleming

Epithelial Stem Cells in Pancreatic Regeneration and Neoplasia

Ingrid M. Meszoely

Anna L. Means

Charles R. Scoggins

Steven D. Leach

Inherited Pancreatic Cancer Syndromes

David H. Berger

William E. Fisher

Part II Staging

Pancreatic Cancer: Radiologic Staging

Harmeet Kaur

Evelyne M. Loyer

Elizabeth A. Lano

Chusilp Charnsangavej

Endoscopic Diagnosis and Staging: Endoscopic Ultrasound, Endoscopic Retrograde Cholangiopancreatography

Richard A. Erickson

Laparoscopic Staging

H. J. Kim

K. C. Conlon

Part III Surgery/Therapeutic Endoscopy/Pain Management

Whipple Procedure: 1935 to Present

Richard D. Schulick

Charles J. Yeo

Regional Lymph Node Dissection for Pancreatic Adenocarcinoma

Peter W.T. Pisters

Murray F. Brennan

Pylorus Preservation versus Standard Pancreaticoduodenectomy: Oncologic Controversies

Karen E. Todd

Howard A. Reber

Vascular Resection and Reconstruction for Localized Pancreatic Cancer

Charles R. Scoggins

Ingrid M. Meszoely

Steven D. Leach

A. Scott Pearson

Techniques for Biliary and Pancreatic Reconstruction After Pancreaticoduodenectomy

Jeffrey A. Drebin

Steven M. Strasberg

Transduodenal Local Resection for Periampullary Neoplasms

Bryan Clary

Theodore N. Pappas

Douglas Tyler

Distal Pancreatectomy for Pancreatic Cancer

Gulam Abbas

Gary R. Gecelter

Risks of Perioperative Mortality with Pancreaticoduodenectomy

Laura A. Lambert

John D. Birkmeyer

Endoscopic Palliation for Locally Advanced and Metastatic Disease: Biliary and Duodenal Stents

Kiranpreet S. Parmar

Irving Waxman

Celiac Plexus Block versus Systemic Opioid Medication in the Management of Pancreatic Cancer Pain

Suresh K. Reddy

Lurry L. Zhou

Part IV Multimodality Therapy

Postoperative Adjuvant Therapy: Past, Present, and Future Trial Development

William F. Regine

Preoperative (Neoadjuvant) Therapy for Resectable Adenocarcinoma of the Pancreas

Wayne A.I. Frederick

Robert A. Wolff

Christopher H. Crane

Jeffrey E. Lee

Peter W.T. Pisters

Douglas B. Evans

European Adjuvant Trials

Paula Ghaneh

David Smith

Jennifer Almond

Deborah Moffitt

Janet Dunn

John Slavin

Robert Sutton

Claudio Bassi

Paolo Pederzoli

Hans G. Beger

Karl H. Link

Helmut Freiss

Markus Buchler

John P. Neoptolemos

Adjuvant Regional Infusion Therapy

Two-Channel Chemotherapy to Prevent Hepatic Metastasis After Extended Pancreatectomy for Adenocarcinoma of the Pancreas: The Osaka Experience

Osamu Ishikawa

Hiroaki Ohigashi

Terumasa Yamada

Yo Sasaki

Masao Kameyama

Masahiro Hiratsuka

Toshiyuki Kabuto

Shingi Imaoka

Adjuvant Intra-arterial Chemotherapy With and Without Radiation Therapy in Pancreatic Cancer: The Ulm Experience

Frank Gansauge

Karl H. Link

Andrea Formentini

Miriam Schatz

Erwin Rottinger

Johannes Gorich

Hans G. Beger

Locoregional Targeting Immunochemotherapy for Resectable and Unresectable Pancreatic Head Carcinoma: The Athens Experience

Nikolaos J. Lygidakis

Labros Vlachos

Sotirios Raptis

George Rassidakis

Christos Kittas

Intraoperative Radiation for Pancreatic Cancer

Nora A. Janjan

Christopher H. Crane

Conformal Radiation Therapy in Pancreatic Cancer

Christopher H. Crane

Nora A. Janjan

Radiation Sensitizers, Fractionation Schedules, and Future Clinical Trials

A. William Blackstock

Cytotoxic Chemotherapy for Pancreatic Cancer: Past, Present, and Future

Robert A. Wolff

Part V Emerging Therapies

Animal Models of Pancreatic Adenocarcinoma

Ramon E. Jimenez

Andrew L. Warshaw

Carlos Fernandez-del Castillo

Strategies for Gene Therapy

Eugene A. Choi

Francis R. Spitz

Photodynamic Therapy and Endoscopic Ultrasound-Guided Therapy for Pancreatic Cancer

Sandeep Lahoti

Vaccine Therapy for Pancreatic Cancer

Eileen M. O'Reilly

Antiangiogenic Strategies in Pancreatic Cancer

Christiane J. Bruns

Lee M. Ellis

Robert Radinsky

Role of Matrix Metalloproteinase Inhibition in the Treatment of Pancreatic Cancer

Alexander S. Rosemurgy II

Mahmudul Haq

Regulation of Pancreatic Cancer Growth by Gastrointestinal Hormones: A Clinically Useful Strategy?

William E. Fisher

David H. Berger

Farnesyltransferase Inhibitors: Biological Considerations for Future Therapeutics

Adrienne D. Cox

L. Gerard Toussaint, III

Novel Therapeutic Targets for Drug Development

Daniel D. Von Hoff

Elizabeth R. Campbell

David J. Bearss

Index