Overview

1. Advances in Swine in Biomedical Research

Mike E. Tumbleson

Lawrence B. Schook

General

2. Swine in Physiological and Pathophysiological Research

David R. Brown

James M. Terris

3. Swine as a Model in Cardiovascular Research

Jack E. McKenzie

4. Porcine Endotoxemia: Chemical Mediators and Therapeutic Interventions

Neil C. Olson

5. Bronchial Function in the Porcine Lung-From the Fetus to the Adult

Malcolm P. Sparrow

6. The Pig as a Model for Studying the Pathobiology of Intestinal Transport in Infectious Enteric Disease

Robert A. Argenzio

7. Developments in Breeding Gottingen Minipigs

Peter J. A. Bollen

Lars Ellegaard

8. Evaluation of the Mechanism of Cyclosporine A Nephrotoxicity

David A. Calvert

James M. Terris

9. Functional Modulation of the Porcine Small Intestine: Effects of Opioids and Characteristics of Enteric Opioid Receptors

David R. Brown

Mark A. Osinski

Teresa R. Kowalski

Sutthasinee Poonyachoti

Mary S. Pampusch

Michael P. Murtaugh

10. Ultrastructure of the Liver From Piglets Fed Dietary Oils

Amreek Singh

Cornelia Gilroy

Esmail Shahidi

11. Effects of Fumonisins in Swine: Implications for Biomedical Reseach

Wanda M. Haschek

Laura A. Gumprecht

Geoffrey W. Smith

Helen M. Parker

Val R. Beasley

Mike E. Tumbleson

12. Artificial Surfactant as a Vehicle for Endortracheal Epinephrine in Pediatric Porcine Cardiopulmonary Arrest

Melinda S. Jasani

Vinay M. Nadkarni

Michael Szatkowski

John Stefano

Patricia Resnik

Gerald A. Mandell

Steven K. Salzman

13. Age-Related Cardiovascular Responses to Phenyl Biguanide in Piglets

Shiwei Tong

Isaac D. Frasier

Susan Ingenito

Anthony L. Sica

Norman Gootman

Phyllis M. Gootman

14. Differential Effects of Left and Right Cardiac Sympathetic Denervation on Ventricular Fibrillation Threshold in Developing Swine

Shiwei Tong

Susan Ingenito

Isaac D. Frasier

Norman Gootman

Phyllis M. Gootman

Transgenics

15. Transplantation and Genetic Manipulation in Porcine Systems

Mark S. Rutherford

16. Immunologic Advances Towards Clinical Xenotransplantation

Shu S. Lin

Jeffrey L. Platt

17. Assessment of Public Health Aspects of Porcine Xenotransplantation

Peter J. Matthews

George W. Beran

33. Pathogenesis of Enteric Bacterial Infections

Richard E. Isaacson

34. Aujeszky's Disease (Pseudorabies): A Natural Host-Virus Model of Human Herpesviral Diseases

Gail Scherba

Federico A. Zuckermann

35. Establishment of Latency in the Natural Host Animal by Aujeszky's Disease (Pseudorabies) Virus Lacking the Putative LAT Gene Promoter

Ling Jin

William M. Schnitzlein

Gail Scherba

36. Pathogenesis of Viral Infections

Richard C. Wardley

Stephen Martin

Linda J. Sair

Author Index

Subject Index

18. Porcine Model of Orthotopic Liver Transplantation for Chronic Studies: Results of Initial Two Week Investigations of Biochemical Parameters and Hepatic Hemodynamics

Mohammed Sika

James G. Drougas

Yolanda T. Becker

William C. Chapman

J. Kelly Wright

Kevin L. Donovan

Volker I. Striepe

David B. Van Buren

Kathy A. Stokes

Sue Ellen Barnard

Kimberly Taylor Blair

Kareem Jabbour

Phillip E. Williams

C. Wright Pinson

19. Genetic Engineering of Swine

Vernon G. Pursel

Morse B. Solomon

Robert J. Wall

20. Development of Swine Embryonic Stem (ES) Cells

Laurie A. Rund

Gregory T. Bleck

Melissa M. Izard

Linda R. Grum

Raymond W. Gerfen

Matthew B. Wheeler

21. PCR-RFLP Genotyping of SLA-DQB and SLA-DRB Alleles

Mark S. Rutherford

Xuexian Zhang

Lawrence B. Schook

22. Identifying Tumor Initiator/Suppressor and Penetrance Associated Genes by Gene Mapping

Timothy P. L. Smith

Craig W. Beattie

Immunology and Infectious Deseases

23. Immunology and Infectious Diseases of Swine

Reinhard Pabst

Gail Scherba

24. The Functional Structure of the Pig's Immue System, Resting and Activated

Richard M. Binns

Reinhard Pabst

25. Immunological Functions of the Intestinal Lamina Propria

Mick Bailey

Karen Haverson

Christopher R. Stokes

26. Soluble Effector and Regulatory Functions in the Porcine Immune System

Michael P. Murtaugh

John E. Butler

Bernard Charley

27. Swine Have a Single JH, 20 VH Genes and No IgD: Are They Suitable Immunological Models for Humans?

John E. Bulter

Jishan Sun

Pedro Navarro

28. Cellular Immune Responses Controlling Infectious Diseases

Joan Lunney

Armin Saalmueller

Thomas Pauly

Patricia Boyd

Sarah Hyatt

David Strom

Stephen Martin

Federico Zuckermann

29. Spontaneous Regression of Sinclair Swine Cutaneous Malignant Melanoma

Max S. Amoss, Jr.

Valeria A. Fadok

Asha S. Multani

Sen Pathak

John F. Greene, Jr.

John W. Measel, Jr.

Clinton D. Morgan

30. The Human and Swine CD4/CD8 Double Positive T Lymphocyte

Federico A. Zuckermann

Robert J. Husmann

31. Defining the Isoforms of Porcine CD45

William M. Schnitzlein

Federico A. Zuckermann

32. Associations between Stress-Susceptibility and Immune Status in Pigs