Product Description: Serotonin (5-HT) was isolated and chemically characterized nearly four decades ago, and is now generally accepted to function as a neurotransmitter and neuromodulatory agent. Early research focused on the measurement of concentrations, synthesis, and metabolism of 5-HT, and only recently has the focus shifted to characterization of 5-HT receptors...read more

Product Description: The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized, and they show a modulatory role in learning and memory processes and food intake...read more

Product Description: This book provides a comprehensive, up-to-date review of the distribution, pharmacology and physiology of central 5-hydroxytryptamine (5-HT)4 receptors. The 5-HT receptor subtypes exhibit a unique pharmacology, distribution and function, of which the 5-HT4 receptor has been one of the most intensively studied in recent years, both from a basic research standpoint and as a target for novel therapeutics...read more

Product Description: This volume provides an up-to-date and comprehensive overview of the anatomy, physiology, and basic and applied pharmacology of CNS serotonin neurons and serotonin receptor subtypes required for understanding the role(s) of serotonin in brain function and in behavior...read more (view table of contents, read Amazon.com's description)

Product Description: An international group of authors have produced an overview of the progress made in the medicinal chemistry of compounds (selectively) acting at serotonin receptors or serotonin transporters either as agonists, partial agonists or antagonists...read more (view table of contents, read Amazon.com's description)

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Product Description: This monograph presents wide-ranging views on the roles of serotonin in various functions, such as sleep, pain, and behavior, as well as new developments in serotonin research. Placing major emphasis on serotonin receptors, it examines the progress made in scientific understanding in the field, including coverage of specific receptors linked to the utilization of inositol phosphate(s) as a second messenger, peripheral serotonin receptors, the production and clinical significance of targeted antagonists to these receptors, and evidence supporting the presence of at least five types of serotonin receptors in the mammalian nervous system, including various experimental strategies and findings on their functional significance...read more