New clinical developments and very practical protocols and outlines for evaluation and treatment are the core of the Third Edition, which provides vital guidance for anyone who interacts clinically with endocrine patients, including endocrinologists, diabetologists, internists, fellows, house officers, medical students, and nurses. New topics covered include Syndrome X, type 2 diabetes in children, the molecular endocrine laboratory, new drugs for both type 1 and type 2 diabetes mellitus, the latest theories on atherogenesis, and the close relationship between insulin and heart disease. Emphasizes concise descriptions of evaluation, management, and treatment.

Iron is of fundamental importance to the growth, development and well-being of almost all living organisms. Multiple biological systems have evolved for the uptake, utilisation, storage, and homeostasis of iron in microbes, plants and mammals. Both iron deficiency and iron overload are found extensively in humans; the intimate links between iron and oxidative stress are associated with a wide range of pathologies. Iron has a well established role in infections by a range of microorganisms and parasites. Other metals such as copper and zinc are also closely linked with iron metabolism. Iron overloads and deficiencies are important factors in the health of humans and are therefore a key target in drug development. Iron Metabolism: From Molecular Mechanisms to Clinical Consequences, 3rd Edition presents a comprehensive overview of this important field.Topics covered include: Solution chemistry of iron in biological media The importance of iron for biological systems Microbial iron transport and metabolism Iron uptake by plants and fungi Cellular iron uptake and export in mammals Intracellular iron storage and biomineralization Intracellular iron metabolism and cellular iron homeostasis Iron absorption in mammals, with particular reference to man, and regulation of systemic iron balance Pathophysiology of iron deficiency and iron overload in man Iron and oxidative stress Brain iron homeostasis and its perturbation in various neurodegenerative diseases Interactions between iron and other metals Written in a lively style by one of the leaders in the field and presented in full colour, this third, expanded edition of Iron Metabolism has been fully updated with the latest discoveries. Major additions include recent information on mitochondrial iron metabolism and the role of frataxin; transcriptional control of iron homeostasis; orally active iron chelators; the roles of hepcidin and erythropoietin; the increasing number of types of iron overload; and the importance of iron in Alzheimer’s disease.  Iron Metabolism is essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and the medical sciences.  It will also find space on the bookshelves of bioinorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, and pharmacologists in the pharmaceutical industry interested in developing novel iron-binding drugs.

Product Description: This issue of Endocrinology and Metabolism Clinics examines the timely topic of Lipidology. In addition to the New Recommendations - ACC/AHA Lipid Guidelines, the issue also includes Familial Hypercholesterolemia; LDL Apheresis; Lipids in Pregnancy and Women; Diabetes and Lipidology; Diabetic Dyslipidemia; Fatty Liver Disease; Lipids and HIV Disease; Residual Risk; and Statins' effects on diabetes, cognition, and liver safety...read more

Product Description: How the Endocrine System Works is not another standard introduction to endocrinology, but an innovative and fun way to learn about the importance of the key glands in the human body and the hormones they control. It is explained in 9 easy-to-understand lectures, with additional material on the treatment and management of endocrine disorders...read more

Product Description: Establishing endocrinology as a distinct medical specialty was no easy task. This engaging volume chronicles the journey through the stories of the men –and occasional women—who shaped the specialty through the ages. In 108 brief chapters, A Biographical History of Endocrinology illuminates the progress of endocrinology from Hippocrates to the modern day...read more

The purpose of this book is to try to explain the biological and clinical behaviour of tumours of the human thyroid follicular cell in terms of their underlying genetic and biochemical abnormalities. As a background, the mechanisms controlling normal thyroid cell division are discussed before considering the changes occurring in tumour cells. The development of the various stages of tumourigenesis is discussed in the light of modern concepts of neoplasia, emphasizing particularly the fundamental role of oncogenes. Older studies of experimental thyroid carcinogenesis are also included and re-evaluated to the more recent data. This book should be of interest to pathologists and endocrinologists wishing to know more of the basic biology of thyroid tumours. and also to non-clinical cancer biologists.

Product Description: Thoroughly revised and extensively expanded, this encyclopedic, highly acclaimed title addresses all aspects of the etiology, pathogenesis, diagnosis, initial treatment and long-term management of all varieties of thyroid cancer. Expertly edited by Drs...read more

Product Description: Part memoir, part cookbook, and all rock and roll, Red Velvet Underground tells the story of how musician Freda Love Smith's indie-rock past grew into her family- and food-centric present. Smith, born in Nashville and raised in Indiana, is best known as the drummer and co-founder of bands such as the Boston-based Blake Babies, Antenna, and the Mysteries of Life...read more

Product Description: This issue of Endocrinology and Metabolism Clinics, edited by Drs. Nanette Santoro and Lubna Pal, is devoted to Postmenopausal Endocrinology.  Articles in this issue include: Endocrinology of Menopause; Menopausal Symptoms; Bone Health and Osteoporosis; Surgical Menopause; Premature Menopause; Cardiovascular Changes; MHT: Current Considerations; Breast Cancer and Hormones; Other Cancers and Menopause; CAM for Menopausal Symptoms; Menopause and Sexuality; and Menopause and Metabolism...read more

Since the first description of Hashimoto disease appeared in 1912, understanding of the disease has greatly altered. The aim of this volume is to describe the latest concepts of immunogenetics, clinical aspects and cellular and humoral autoimmunity of Hashimoto disease. The volume focuses on the definition, criteria, classification, diagnosis and etiology of the disease.

Product Description: Exposure to chronic stress has cumulative adverse effects on physical and mental health, considered to be the consequence of chronic exposure to high levels of stress hormones. Consequently, there is extensive research in progress to investigate and better understand how the brain organises neuroendocrine stress responses and how interventions may be able to moderate these responses to improve mental and physical health...read more

Product Description: A new title in this popular series profiles the hippo, from its extraordinary size, to its social routines, habitat, and much more. With clear, simple text, accompanied by abundant color photos, this title is a great introduction to research routines and nonfiction.

Product Description: This fluffy feline is perfect for a family home. Birmans love both affection and play, but are quiet and refined as well. Some of their favorite things to do are play with interactive toys and run around with other pets. Cuddle up with this silken cat in this fun title for beginner readers...read more

Product Description: This is a series of contemporary techniques and diagnostic advances for adrenal conditions. It covers various pathological alterations of adrenal glands, clarifying the more problematic areas of evaluation. It also focuses on newly-recognized entities, such as macronodular cortical hyperplasia...read more