Product Description: Originally published in 1955, on behalf of the Institute of Actuaries and the Faculty of Actuaries, this book forms the first of two volumes on actuarial practice in relation to mortality and other investigations. Taken together, both volumes were written to meet the requirements of the Examination Syllabus of the Institute of Actuaries...read more

America's Civil War and violent attempts by the Indians to regain their land in Minnesota force the Nilsson family--emigrants from Sweden and now citizens--to demonstrate their strength and courage once again

Product Description: The premise of Quality by Design (QbD) is that the quality of the pharmaceutical product should be based upon a thorough understanding of both the product and the manufacturing process. This state-of-the-art book provides a single source of information on emerging statistical approaches to QbD and risk-based pharmaceutical development...read more

This Handbook is a reference for all aspects of the field of health services and outcomes research. It addresses the increasing need for comprehensive, yet balanced, information in a field that welcomes various disciplines: medicine, public health, statistics, economics, management, policy, and information technology. This well-organized reference is an indispensable source of information for everyone who seeks to develop understanding of health systems and to learn about historical, political, and socioeconomic factors that influence health policies at the global, national, regional and local level. Specifically, the Handbook helps readers: Recognize core concepts of health services and outcomes research, such as, need, access, equity, quality and safety; Become familiar with social, political, organizational, behavioral and economic theories that have influenced health systems designs; Learn about frameworks developed for evaluating the organization, financing, delivery, utilization and outcomes of health services; Get an introduction to methods of comparative effectiveness research, program evaluation, health technology assessment and health economics; Identify types and sources of data appropriate for generating valid and reliable information about the delivery of health services; Learn about strengths and weaknesses of various research designs used to study health services and policy issues. The online version of Health Care Systems and Policies is in the format of a dynamically updated knowledge base, offering search tools, cross-referencing across chapters and linking to supplement data, other major reference works and external articles. The Handbook is accessible at the level of graduate students even if it is not their focus area. This includes students with various backgrounds: medicine, public health, statistics, economics, management or information technology.

Product Description: This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to stop the trial prematurely under control of the Type I error rate...read more

Product Description: The Handbook of Health Services Research is a reference for all aspects of the field of health services and outcomes research. It addresses the increasing need for comprehensive, yet balanced, information in a field that welcomes various disciplines: medicine, public health, statistics, economics, management, policy, and information technology...read more

Product Description: This book presents a systematic and comprehensive treatment of various prior processes that have been developed over the past four decades for dealing with Bayesian approach to solving selected nonparametric inference problems. This revised edition has been substantially expanded to reflect the current interest in this area...read more