Product Description: Pathology of Laboratory Rodents and Rabbits has become a standard text for both veterinary pathologists and veterinarians in laboratory animal medicine. Newly recognized infectious diseases continue to emerge and molecular methods for studying infectious agents are becoming widely used for the classification of these and previously known pathogens...read more

Product Description: This volume provides a comprehensive overview of advanced research in the field of efficient, clean and renewable energy production, conversion and storage. The ten chapters, written by internationally respected experts, address the following topics: (1) solar and wind energy; (2) energy storage in batteries; (3) biomass; and (4) socio-economic aspects of energy...read more

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Product Description: The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science...read more

Product Description: In Motor Activity and Movement Disorders thirteen state-of-the-art articles explicate forefront research methodologies for measuring and interpreting motor activity in animals, as well as their applications to preclinical and clinical research involving motor disorders...read more

Since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States. By addressing questions and problems that often confront institutions, The IACUC Handbook, Second Edition provides accurate, succinct answers. It features comprehensive updates for all pertinent federal laws, regulations, and policies. It also contains an expanded survey of IACUC practices from institutions around the nation. With accessible information, this new editionprovides a foundation for those attempting to understand and implement the many and varied responsibilities of these committees.

Product Description: Toxicity Assessment Alternatives: Methods, Issues, Opportunities contains a broad array of critical surveys, contributed by active and respected investigators, describing their research and offering updates on toxicity assessment alternatives, directions determined by current and future grant programs, opportunities for mechanistically based test methods to detect endocrine disruptor activity, the use of alternatives in the Department of Defense hazard assessment initiatives, and the issues and opportunities for validation and regulatory acceptance...read more

Product Description: This book presents essential information on the use of the immunodeficient C.B.-17 SCID/SCID mouse for studying human hematopoiesis in vivo. Because of the lack of both humoral and cellular immunity, this mouse can be a unique host for implantation of human hematopoietic tissue using different methods...read more

Product Description: Scientists are coming under increasing pressure from activist groups to stop animal experimentation, branded as cruel and unnecessary for improving human health. This attitude, however, stems from an unrealistic evaluation of the situation and distorted information about present scientific knowledge...read more

Product Description: 9. REFERENCES 90 CHAPTER 9: OPPORTUNITIES FOR REPLACEMENT, REDUCTION AND REFINEMENT: HUMAN VIRAL VACCINES 93 1. INTRODUCTION 93 2. TESTS FOR EXTRANEOUS MICROORGANISMS 94 3. MUMPS VACCINE . . . 94 4. HEPATITIS B VACCINE 95 4. 1. Test for freedom from live hepatitis virus 95 4...read more

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This completely revised edition of The Rat Brain in Stereotaxic Coordinates, the second most cited book in science, represents a dramatic update from the previous edition. Based on a single rat brain, this edition features an entirely new coronal set of tissue cut in regular 120 micron intervals with accompanying photographs and drawings of coronal, horizontal and sagittal sections of this new set. The use of the single brain allows for greater consistency between sections, while advances in histochemistry techniques provides increased refinement in the definition of brain areas, making this the most accurate and detailed stereotaxic rat atlas produced to date. The atlas will also include a CD-ROM featuring all of the graphics and text. Every lab working with the rat as an experimental animal model will want to use this book as their atlas of choice.This book is also available in a softcover spiral binding at the same price. * Includes twice as many coronal sections, nissl plates, and sagittal plates as the previous edition * Uses a single rat brain allowing for better consistency and better delineations in the line drawings of structures * Provides improved stereotaxic coordinates at a higher level of detail * Accompanying CD-ROM features graphics and text* Now available as hardcover version and softcover version with a spiral binding at the same price.

Product Description: This book represents a major innovation in the institutional analysis of cities and their planning, management and governance. Using concepts of transaction costs and property rights, the work shows systematically how urban order evolves as individuals co-operate in cities for mutual gain...read more

Product Description: Presents the latest research on the analysis, metabolism, function, and physicochemical properties of fiber, fiber concentrates, and bioactive isolates--exploring the effect of fiber on chronic disease, cardiovascular health, cancer, and diabetes...read more

Product Description: A comprehensive review of recent scientific evidence examining the contributions of animal experimentation to human healthcare. The book also explores toxicity prediction, animal use during life and health sciences education, impacts on student attitudes toward animals, and the extent to which animals suffer in laboratories...read more

As the editors of the first book on the squirrel monkey prophesied in 1968,* there has been an incredible expansion in primate research during the past 16 years. Their projection that the squirrel monkey would play an increasingly important role in this research effort has also come to be true during the ensuing years. One inadvertent result of the rapid growth, however, is that it has become more and more difficult for investigators to keep track of new information, both in their own disciplines and in related fields. For scientists who study and use the squirrel monkey in research, this problem is particularly pronounced, because articles are often published in specialized and disparate journals. We felt that a new synthesis of the vast amount of information on Saimiri would resolve this problem and would provide an extremely valuable com­ panion volume to the first book. The idea grew out of a small symposium held at the IX Congress of the International Primatological Society in Atlanta, Geor­ gia, during August, 1982. Following the format of The Squirrel Monkey, ad­ ditional authors were invited to discuss advances in areas which had experi­ enced exceptional growth or to review basic information that would be of practical value to future researchers. Even with focused topics and synthetic reviews, the wealth of new data resulted in many long manuscripts. In response to the continuing problems with Saimiri nomenclature, Richard Thorington has provided us with a definitive statement on squirrel monkey taxonomy.

Product Description: This book contains the proceedings of the Serono Symposia USA interna­ tional symposium on Genetic Models of Immune and Inflammatory Dis­ eases held on October 20 to 23, 1994, in Savannah, Georgia. The advent of methods for introducing genes into the germlines of mice, and for targeted disruption of particular genes by homologous recombination, has provided scientists in many disciplines with an extraordinarily powerful set of analyti­ cal tools...read more

Product Description: The publication of research articles involving animal studies is central to many disciplines in science and biomedicine. Effective descriptions in such publications enable researchers to interpret the data, evaluate and replicate findings, and move the science forward...read more