Product Description: Autosomal dominant inheritance means an abnormal gene from one parent can cause disease, even though the matching gene from the other parent is normal. The abnormal gene dominates. In this book, the authors present new research in autosomal dominant disorders...read more

Product Description: Based on original ethnographic research with scientists, clinicians and families, this book examines Rett syndrome to illuminate more general issues concerning the construction and interpretation of diseases and syndromes. It derives from research with a specialist team of clinicians and scientists, and a series of families referred with a potential diagnosis of Rett syndrome, and documents the scientific, clinical, patient and family experiences over a three-year period...read more

From a beloved master of crime fiction, The Empty Copper Sea is one of many classic novels featuring Travis McGee, the hard-boiled detective who lives on a houseboat.Asking for help is something a proud man like Van Harder would never do. So when he shows up at the Busted Flush, Travis McGee knows that he must be the man’s last resort. What Harder wants salvaged is his reputation. After a long career as a seaman, he was piloting a boat the night his employer fell overboard. Harder is certain he’s been set up, but to help him, McGee must prove that a dead man is actually alive.“John D. MacDonald is a shining example for all us in the field. Talk about the best.”―Mary Higgins ClarkThe fateful ride started with Harder at the helm of Hubbard Lawless’s luxury cruiser. It ends with him coming to, fuzzy and disoriented, and Hub lost to the water. Now everyone is saying that Harder got drunk, passed out, and is negligent in his boss’s death. The thing is, Van’s not a drinker…at least, not anymore.Who would want to frame the good captain, and to what end? Dead or alive, Lawless is worth a lot of money. People are always eager to get a piece of that action―including some, as McGee soon finds, who are willing to take a piece out of anyone who gets in their way.

Product Description: This ground-breaking resource demonstrates how genetic knowledge can influence our understanding of a child's behaviour and therefore inform their behavioural support plan. With expert advice and clear instructions, it shows exactly how to go about incorporating syndrome knowledge into ABA practice and start treating children with specific genetic syndromes more effectively...read more

Product Description: The latest title in the Salem Health series, Genetics & Inherited Conditions provides comprehensive, non-specialist inforamtin on an array of topics. Essays discuss the growth of our genetic knowledge - from the human genome, stem cells, and common inherited conditions, to the ehical and sociocultural issues...read more

Product Description: The latest title in the Salem Health series, Genetics & Inherited Conditions provides comprehensive, non-specialist inforamtin on an array of topics. Essays discuss the growth of our genetic knowledge - from the human genome, stem cells, and common inherited conditions, to the ehical and sociocultural issues...read more

Product Description: Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males...read more

Product Description: This book shows how the mitochondrial genome is transmitted, segregated and inherited. Opens by describing mtDNA mutations and deletions and showing how these impact the offspring’s well-being, covers mtDNA transmission and discusses transmittal and adaptation.

Product Description: Anthony Killeen, MD, PhD, offers a comprehensive yet concise introduction to molecular pathology that encompasses both applied and theoretical knowledge. Writing in a very readable style, the author reviews the basic concepts of human molecular biology, explains the principles of the most commonly used analytical methods, and discusses the molecular principles that underlie both inherited diseases and acquired genetic abnormalities that lead to cancer...read more

Product Description: Human beings normally have a total of 46 chromosomes, with each chromosome present twice, apart from the X and Y chromosomes in males. Some three million people worldwide, however, have 47 chromosomes: they have a small supernumerary marker chromosome (sSMC) in addition to the 46 normal ones...read more

Product Description: The contributors to The Story Within share powerful experiences of living with genetic disorders. Their stories illustrate the complexities involved in making decisions about genetic diseases: whether to be tested, who to tell, whether to have children, and whether and how to treat children medically, if treatment is available...read more

W. French Anderson, M.D. The publication of this book comes at an opportune time for the young field of human gene therapy. After a decade of long struggle at the laboratory bench and many long hours under the harsh lights of the federal review process, gene therapy has emerged as a legitimate scientific discipline. It is now time to move away from the period of questioning whether gene therapy will be a useful part of the physician armamentarium to begin to actively teach the concepts and practices that make gene therapy a reality. This book is a comprehensive collection of chapters that describe the basic biology and potential application of viruses as gene transfer reagents. It is not a coincidence that a modified virus was the reagent used in the first human gene therapy trials. Viruses have evolved with the human species (and most likely with all forms of life) to be the masters of gene transfer.