Product Description: Provides a review of novel pharmaceutical approaches for Tuberculosis drugsPresents a novel perspective on tuberculosis prevention and treatmentConsiders the nature of disease, immunological responses, vaccine and drug delivery, disposition and responseMultidisciplinary appeal, with contributions from microbiology, immunology, molecular biology, pharmaceutics, pharmacokinetics, chemical and mechanical engineerin...read more

Product Description: This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications...read more

Product Description: Drug delivery systems and pharmaceutical nanocarriers that respond to different types of stimuli, such as internal ones, intrinsic for the pathological area (changes in pH, temperature, redox condition, activity of certain enzymes), or external, artificially applied (magnetic field, ultrasound, various irradiations), represent an important and continuously growing area of research...read more

Product Description: Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices...read more

Product Description: Provides solutions for two- and three-dimensional linear models of controlled-release systemsReal-world applications are taken from used to help illustrate the methods in Cartesian, cylindrical and spherical coordinate systemsCovers the modeling of drug-delivery systems and provides mathematical tools to evaluate and build controlled-release devicesIncludes classical and analytical techniques to solve boundary-value problems involving two- and three-dimensional partial differential equationsProvides detailed examples, case studies and step-by-step analytical solutions to relevant problems using popular computational softwar...read more

Product Description: This symposium provided a setting in which scientists could gather to discuss recent advances and state-of-the-art technology in drug delivery. Speakers included pharmaceutical scientists, polymer chemists, bioengineers, pharmacologists and physicians who were considered to be leaders in the field of research and development of drug delivery systems...read more

This edition of Shakespeare's Henry IV, Part 1 uses a variety of approaches to Shakespeare, including historical and cultural studies approaches. Shakespeare's text is accompanied by an intriguing collection of thematically arranged historical and cultural documents and illustrations designed to give a firsthand knowledge of the contexts out of which Henry IV, Part 1 emerged. Hodgdon's intelligent and engaging introductions to the play and to the documents (most of which are presented in modern spelling and with annotations) offer a richly textured understanding of Elizabethan culture and Shakespeare's work within that culture.

The 2003 edition of this best-selling handbook has been revised with hundreds of new drug facts and approximately 10 to 15 new monographs for FDA-approved IV drugs. Revised annually, it provides detailed information for more than 350 drugs in a clinically useful format. Acclaimed for its consistency, comprehensiveness, and accuracy, this handbook gives health care personnel quick access to complete, authoritative IV drug information.Provides coverage of more than 350 IV drugs alphabetically by generic name for quick clinical reference in any settingLists dosage information for each drug on a single- or two-page spread to ensure that the health care worker does not contaminate his or her hands by having to turn the page.Provides all the essential clinical information on IV drug administration in an easy-to-use format.Highlights dose variances in special sections for geriatric, pediatric, infant, and neonatal patients.Lists all side effects and incompatibilities in alphabetical order for quick access.Includes over 100 concise, easily accessible charts detailing dosing guidelines, dilution guidelines, recommended dose modifications, combination schedules, infusion rates, contraindications, and more.Ensures fast, easy access to desired information with extensive cross-referencing.Provides valuable patient education information, as well as coverage of unlabeled uses, is included when applicable.Includes helpful appendixes to provide quick, valuable guidance: Recommendations for the Safe Handling of Cytotoxic Drugs (Appendix A); Alternate Choices for Infrequently Used Drugs (Appendix B); FDA Pregnancy Categories (Appendix C); Information for Patients Receiving Immunosuppressive Agents (Appendix D); and National Cancer Institute Common Toxicity Grading Criteria (Appendix E).Highlights Important IV Therapy Facts at the beginning of the book.General Dilution and Solution Compatibility Charts provide a fast and easy reference in the clinical setting.Highlights each new monograph with lightly shaded monograph headings for quick readability and focus.Support practical use in the clinical environment with the spiral binding and portable size.Indicates exclusive Canadian availability with Canadian maple leaf icon preceding the trade name.

Product Description: This book presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles.

Recent years have seen enormous advances in the field of protein and peptide engineering and a greater understanding in the way in which biological response modifiers function in the body. It is now possible through the use of recombinant DNA techniques, or by solid phase protein synthesis, to produce significant quantities of a wide variety of regulatory agents that are therapeutically applicable. The list of these response modifiers expands almost daily to include interferons, macrophage activation factors, neuropeptides and agents that may have potential in cardiovascular disease, inflammation, contraception etc. Prospects to use some of these materials in medicine have reached the stage where products have either been approved by regulatory authorities or are the subject of applications as investigatory drugs or as new therapeutic agents. In some uses the pertinent agent will be administered on an acute basis in the form of a simple injection, as, for example, the use of a tissue plasminogen activator for the treatment of coronary infarct. In other cases regulatory proteins and peptides are indicated for chronic therapy and here they will need to be administered by an appropriate delivery system. Unfortunately, the research on delivery systems for peptides and proteins has not kept pace with the rapid progress in biotechnology and, consequently, there are presently few systems that are entirely appropriate for the administration of macromolecular drugs according to complex dosage regimens, (eg intermittent and pulsed therapy). Furthermore essential pharmacokinetic and pharmacodynamic data may be missing.