Product Description: In this book Mircea Steriade cautions against the tendency of some neuroscientists to infer global brain functions such as arousal and sleep, epileptic events, and even conscious thinking from the properties of single cells. Based on his lifetime of research on intact brains, Steriade emphasizes the need to understand isolated networks within the context of the whole mammalian brain and to understand the brain of a behaving animal in terms of its fully dissected circuits...read more

Product Description: Brain Slices in Basic and Clinical Research describes advancements in the field of brain function and dysfunction through use of central nervous system slice preparations. Topics are authored by leading scientists and include the following:Mechanisms of synaptic plasticity as the basis of memory processesChaos and synaptic variabilityBrain calcium currentsGlutamate receptorsPathophysiology of excitotoxinsCerebral hypoxia-ischemiaNeuronal injuryFree radicalsOptical methods of measuring brain metabolismVoltammetry in brain slicesCalcium imagingPatch-clamp recording and application of macromolecules through patch-clamp pipettes in brain slicesIntracellular double labeling of various neuronal populationsUse of brain slices in teaching neurophysiological methodsMost of the topics are published in book format for the first time, and some of the techniques are more fully detailed than in any other book...read more

Product Description: This volume brings together both classic papers and specially commissioned chapters on how neural systems interact to produce or influence observed behavior patterns. The first part focuses on the necessity for the unique strengths of a descriptive neuroethological approach to studying brain-behavioral relations...read more