This volume covers the latest developments in optical imaging of the brain which is becoming an increasingly important functional neuroimaging method. Optical intrinsic signals offer unrivaled temporal and spatial resolution of functional measurements of the exposed brain cortex in animals and humans. Near-infrared spectroscopy and imaging ap­ proaches permit the noninvasive functional assessment of the human brain at bedside. Main advantages of these optical techniques are the biochemical specificity of the meas­ urements and the potential of measuring correlates of intracellular and intravascular oxy­ genation simultaneously. Recent data indicate that one may also measure a more direct correlate of neuronal activity associated with changes in light scattering. In this volume, recent technical progress of the optical method is covered as well as the physiological basis of the measurements. In simultaneous studies, near-infrared spec­ troscopy measurements are directly compared to other functional methods, especially PET and fMRI and examples are given for new applications of the NIRS-method. Based on re­ sults obtained with optical methods and other functional techniques the latest in our under­ standing of the coupling of neuronal activity and cerebral blood flow response is reviewed. This is an important basis for a better understanding of all functional neuroi­ maging methods which rely on neurovascular coupling such as PET, SPET and fMRI. Fi­ nally the optical method is put into the perspective of presently available functional neuroimaging methods including fMRI, PET, MEG and EEG.

Product Description: This book constitutes the refereed proceedings of the Second International Workshop on Multimodal Brain Image Analysis, held in conjunction with MICCAI 2012, in Nice, France, in October 2012. The 19 revised full papers presented were carefully reviewed and selected from numerous submissions...read more

Product Description: The advent of non-invasive neuro-imaging (computerized tomography) marked the beginning of a new era in our understanding of psychiatric illness. A variety of neuroimaging techniques have since become available which made it possible to detect subtle structural brain abnormalities in the major psychiatric disorders, to identify dysfunctional brain circuits that may be disease or symptom specific, and to study underlying neurotransmitter abnormalities and how they can be pharmacologically modified...read more

Product Description: This text covers topics in medical imaging and includes four sections which looks at lung imaging, general physiologic imaging, cardiovascular imaging, and brain imaging.

Product Description: This book is a compilation of papers by scientists from various areas of biophysical and biochemical techniques, with the aim of exploring ways in which multidiscipline approaches can be brought to deepen understanding of how the brain works.

Product Description: This is a unique and richly illustrated book that concisely explains topographic mapping of electrical and magnetic brain activity, and relates this technique to metabolic and regional blood flow studies. Also addressed are important results of experimental and clinical investigations, as well as problems of electrical magnetic data and topographic display...read more