Product Description: The Forest Runners

Product Description: The Border Watch

Product Description: ing Lear is a tragedy written by William Shakespeare. It depicts the gradual descent into madness of the title character, after he disposes of his kingdom giving bequests to two of his three daughters based on their flattery of him, bringing tragic consequences for all...read more

Product Description: Media Law for Producers is a comprehensive handbook that explains, in lay terms, the myriad legal issues that the producer will face on a regular basis - contracts, permits, defamation, patents, releases and insurance, libel, royalties and residuals, as well as protecting the finished production...read more

Product Description: This fiction title is paired to the nonfiction title "My Farm" for connecting across texts and comprehension through connection strategies.

Perhaps as many as 50 in every 100 mentally ill patients are parents living with their children. It is well established that mental illness in a parent seriously and often adversely affects their children's development, though strangely this is not adequately reflected in clinical service provision. It is hoped that, through the experiences and studies described, this volume will provide an impetus to redress this deficit. This innovative book covers hitherto uncharted territory. By drawing together clinical experience from a wide range of centres, it effectively addresses the needs of mentally ill parents and their children; helping to bridge the current gap between adult and children's services and foster a family oriented perspective. The wide range of editorial experience from both social work and psychiatry at research and clinical levels are vital attributes in providing depth and breadth to this multidisciplinary volume. Enlivened by case vignettes, the coverage ranges from medical and general psychological and psychiatric issues through to intervention strategies and clinical service provision. It will be sure to interest all professionals dealing with adult mental illness and child care issues.

Product Description: Frightfully Friendly Ghosties, described as "exciting, charming and ridiculous," by The Guardian, is a hilarious book for young readers about the adventures of a funny, charming, and terribly polite group of ghosts who just want to get along with their housemates...read more

Product Description: Bright photos and easy-to-read descriptions examine the various animals who live in the warm waters around a coral reef.

Product Description: Felix Hausdorff gehört zu den herausragenden Mathematikern der ersten Hälfte des 20. Jahrhunderts. Er hinterließ einen ungewöhnlich reichhaltigen Korpus wissenschaftlicher Manuskripe. Sein Gesamtwerk soll nun in 9 Bänden, jeweils mit detaillierten Kommentaren, herausgegeben werden...read more

Cellular drug resistance is a major limitation to the success of chemotherapy of leu­ kemia and lymphoma. The importance of this has now been recognized by both clinicians and scientists. It is of utmost importance to bridge the gap between laboratory and clinic in this field of research. This is the main purpose of the series of International Symposia on Drug Resistance in Leukemia and Lymphoma. These are held every three years in Am­ sterdam, The Netherlands, since 1992. This book contains the proceedings of the third of these meetings, organised in 1998. The book covers all important aspects of drug resistance in leukemia and lymphoma, both in the form of extensive reviews as in manuscripts describing original data. General mechanisms of resistance are discussed, including the drug resistance related proteins p­ glycoprotein, MRP (multi-drug resistance protein) and LRP (lung resistance protein), and the role of glutathione and glutathione-S-transferases. Moreover, more drug type-specific mechanisms of resistance are a topic, such as for glucocorticoids and antifolates. Much in­ formation is provided on apoptosis and its regulators, and on the results of cell culture drug resistance assays. Several papers focus on the modulation or circumvention of drug resistance.

Product Description: Completely revised and updated for 2013 and now in its twelfth edition, Antibiotic Essentials 2013 is a leading antimicrobial/infectious disease pocket guide for clinicians. The book’s contributors are leading world experts in their fields from various distinguished institutions...read more

Product Description: Antibody-directed enzyme prodrug therapy (ADEPT) directly addresses the major problem in cancer chemotherapy-its lack of selectivity. Antibody delivery combined with the amplification provided by the enzymatic activation of prodrugs enables selection to be made between tumour and normal tissue...read more

HMG-CoA reductase inhibitors (statins) are established drugs for the treatment of hypercholesterolemia. Furthermore, they induce regression of vascular atherosclerosis as well as reduction of cardiovascular-related morbidity and death in patients with and without coronary artery disease. This book deals with statins which have substantially altered the approach to therapy of atherosclerosis and its sequelae. Emphasis is placed on the scientific background to the discoveries and the development of the therapy, including an overview of the current state of knowledge of the drugs. Clinical data are reviewed extensively. This book not only provides the reader with valuable information but also stimulates further research into the pathogenesis of atherosclerosis and the mechanisms behind the action of effective statins. It sets the stage for creative thinking among scientists of many disciplines for the accomplishment of our ultimate goals in treating atherosclerosis and its sequelae. This topical volume...

Product Description: This volume describes recent research in the field of metalloproteinases (a family of enzymes that can catalyze tissue degradation), in particular their participation in autoimmune diseases such as rheumatoid arthritis, reviewing the latest developments in metalloproteinase inhibitor design and the current status of clinical candidates...read more

Product Description: Maurie Markman and a panel of distinguished clinicians and leading clinical investigators comprehensively review the current status of regional antineoplastic drug delivery in the management of malignant disease. These authorities present a critical analysis of both the rationale and limitations of regional therapy and discuss potential clinical trials designed to explain the effectiveness of this method of therapy in special settings...read more

A noted herbalist presents fifteen herbs that can be used effectively in treating a range of drug-resistant ailments--such as pneumonia, ear infections, and meningitis--along with tips on making and using infusions, tinctures, teas, and salves from aloe, echinacea, garlic, and other natural sources. Original. (view table of contents)

Product Description: The purpose of this book is to clarify the use of antibiotics in the management of the eommon respiratory illnesses seen in general practiee. The underlying philosophy, whieh embraees the avoidanee of unneeessary use, is that proper use entails a full understanding of the nature of the illness...read more

Product Description: Completely revised and updated for 2012 and now in its eleventh edition, Antibiotic Essentials 2012 is a leading antimicrobial/infectious disease pocket guide for clinicians. The book’s contributors are leading world experts in their fields from various distinguished institutions...read more

Product Description: Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery...read more

Product Description: This book contains 32 chapters based on the corresponding papers delivered at the International Symposium on Antimicrobial Agents and Immunity, held in Siena, Italy on May 2-4, 1985 as a Satellite Symposium of the Third International Conference on Immunopharmacology, held in Florence, Italy on May 6-10, 1985...read more

Product Description: Soon after the first description of monoclonal antibodies in 1976, there was enormous interest in the clinical application of antibodies, especially in the context of cancer. Antibodies appeared to offer the “magic bullet” that would allow the specific destruction of neoplastic cells...read more

This text aims to introduce advanced medical students and young doctors to the principles of antimicrobial chemotherapy, and to foster good prescribing habits, which are essential if antibiotics are to retain their value for the future. Topics covered include the general properties of antimicrobial agents of all kinds (antibacterial, antifungal, antiviral and antiparasitic), laboratory aspects of antimicrobial chemotherapy, problems of resistance, general principles of treatment (including pharmacokinetic aspects and the special problems of children and the elderly), side effects, chemoprophylaxis, and the treatment of specific groups of infectious diseases. There is a useful postscript on the development of new antimicrobial drugs.