Product Description: This comprehensive text focuses on the systems approach to simulating and predicting pharmacokinetic behavior (including metabolism-based drug-drug interactions), in patient populations using demographic, physiological, and genetic information, as well as input from in vitro studies of drug absorption and disposition...read more

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Product Description: Internationally renowned authorities from diverse fields present the principles and practice regarding the measurement of drug effects in humans and its role in the analysis and development of new chemical entities. The main thrust is on surrogate endpoints, peripheral vascular disease, the reliability of data collection and interpretation as well as the identification, predictability and performance of drug interactions and adverse effects...read more (view table of contents, read Amazon.com's description)