The first edition of Mark Ptashne's 1986 book describing the principles of gene regulation in phage lambda became a classic in both content and form, setting a standard of clarity and precise prose that has rarely been bettered. This edition is a reprint of the original text, together with a new chapter updating the story to 2004. Among the striking new developments are recent findings on long-range interactions between proteins bound to widely separated sites on the phage genome, and a detailed description of how gene activation works. (view table of contents)

Product Description: Genes & Signals analyzes gene regulation from a new perspective. The first chapter describes mechanisms found in bacteria, and two subsequent chapters discuss which of these is most highly exploited in higher organisms. A final chapter relates these molecular strategies to other enzymatic processes, including those involving kinases, RNA splicing enzymes, proteases, and others...read more (view table of contents, read Amazon.com's description)

Product Description: A Genetic Switch is concerned with how a virus called lambda uses its genes - its DNA - to direct its growth. Biologists have long wished to know how genes are 'switched' on and off during development and, aberrantly, in diseased states. (view table of contents, read Amazon.com's description)

Product Description: "A Genetic Switch" is an introduction to gene function - specifically the genetic repressor. Understanding the repressor function is essential to an understanding of biochemical activity within the gene as it is fundamental to the process by which growth and development are regulated at the molecular level...read more