Today we witness an eventful time in which the powerful new forces of genomics, information technology and economics are rapidly changing the science and art of medicine. This will require more specialization than ever before. However, there is also an increasing demand for an integrated approach, which is provided by the discipline of Clinical Pharmacology (CP). CP pursues a scientific goal by studying drug action in patients and volunteers, a clinical goal by administering appropriate drug therapy and a regulatory goal by assessing the risk/benefit ratio of drug candidates in drug development and reimbursement. This introduction to current topics of CP covers traditional topics of clinical drug research and trial methodology but also provides insight in current topics like genomics, imaging technology and issues in drug reimbursement. A number of concrete case studies in clinical drug research and development help to give a better understanding of the general principles of CP.

Product Description: One of the most important sculptors of his generation, Basque artist Eduardo Chillida (1924–2002) created monumental public sculptures that adorn buildings and public places worldwide. From Eulogy to the Horizon to Toleranceby Dialogue to the eighty-ton weathered steel work De Musica, which stands in front of the Meyerson Symphony Center in Dallas, Chillida’s work has enjoyed wide critical acclaim for its ability to convey tensions in space...read more

Product Description: Joe Coleman, who spends months and even years working on a single painting, has described his process as an “internal dig.” His complex, obsessive excavations, which dive into the often violent histories and biographies of subjects like Osama Bin Laden or Joan Collins, certainly create an idiosyncratic and dense experience for the viewer...read more

Product Description: Picasso met Françoise Gilot, the young French student who was to become his muse and favorite model, while waiting out the war years in Paris. She appeared again and again in his works of the 1940s and 50s, often with her face stylized to recall the sun or a plant...read more

Product Description: In honor of "Food", the restaurant which Gordon Matta-Clark established in Soho, New York, this publication is presented in the form of a restaurant menu, and documents the artist's varied and imaginative work, including sculptures, film stills, and photos.