Product Description: Drug design is intrinsically involved in the discovery of a new drug: it can be incorporated into the identification of a lead compound by intelligent screening; involved when a new molecule for synthesis is created by computer or by intuition, based upon an intelligent understanding of the protein target; or in converting compounds such as peptides and carbohydrates into peptidomimetics or carbohydramimetics, retaining the original role of the compound while operating pharmaceutically...read more

Product Description: Over the last few years, the considerable progress made in biochemistry, virology, molecular biology and genetics has revealed some of the intimate mechanisms of the neurodegenerative diseases. The present volume is an attempt to review the latest data in the field to illuminate new avenues for future research...read more

Product Description: This is the sixth Rhone-Poulenc (now Rhone-Poulenc Rorer) Round Table volume and addresses perhaps the most topical subject so far. Toxicologists face a dilemma - how to guarantee consumer safety by implementing the increasingly stringent standards of the regulatory authorities and also drastically reduce animal experimentation? In vitro methods are a possible solution and this volume is specially compiled to report the reviews from a meeting of one hundred experts together with a distillation of their discussions...read more