Product Description: This expert volume covers an interdisciplinary and rapidly growing area of biomedical research comprising genetic, biochemical, pathological, and clinical studies aimed at the diagnosis and therapy of human diseases which are either caused by or associated with mitochondrial dysfunction...read more

Product Description: The concept of mitochondrial diseases originated in 1962 with the description by Luft and coworkers of a patient with nonthyroidal hypermetabolism due to loose coupling of oxidation and phosphorylation in muscle mitochondria. Over the following quarter of century, thanks to W...read more (view table of contents, read Amazon.com's description)

Product Description: This brand-new text provides you with an easy-to-use, comprehensive reference that features a clinical perspective balanced with relevant basic science. Inside, you'll find discussions of the latest research and how it has led to a greater understanding of the cause of disease, as well as burgeoning tests and the latest therapeutic agents available...read more

Product Description: Mitochondrial dysfunction is increasingly being recognized as the basis of a wide variety of human diseases. Providing an authoritative update on our current knowledge of mitochondrial medicine, this text draws together world authorities from various fields to present general therapeutic strategies, as well as the treatments presently available in different specialties - thus making it essential reading for clinicians involved with the management of patients with mitochondrial diseases...read more

Product Description: The United States Congress has designated the 1990s as the "Decade of the Brain" in recognition of the major importance of neurology and the other neurosciences in the health and well-being of Americans. It has been suggested that as many as 20% of all patients seeking medical treatment have neurologic problems, either as the presenting complaint or as an associated condition complicating the primary illness...read more (view table of contents, read Amazon.com's description)

Product Description: Looks at the results of the recent discovery that disorders of the mitochondria have a role to play in many neurological disorders such as muscular degenerative diseases and Parkinson's Disease. Part of the "BIMR" series, this volume discusses this emerging field.

Product Description: This volume examines the genetics, molecular biology, and clinical features of diseases resulting from defects of mitochondrial DNA (mtDNA) and describes current strategies for diagnosing and treating mitochondrial diseases. Coverage includes chapters on diseases associated with spontaneous deletions and duplications, maternally inherited defects, inherited Mendelian defects, and quantitative defects of mtDNA...read more

Product Description: This volume presents molecular and genetic studies that shed new light on the pathogenesis of these diseases. The contributors show how molecular and genetic analyses of mitochondria can explain the variable clinical features of mitochondrial encephalomyopathies and provide a basis for classifying these diseases...read more

Product Description: Written by leaders in the field, this book will give readers a grounding in the basic concepts and language of molecular genetics and a survey of the neurologic and neuromuscular diseases that have been studied with these techniques...read more