Product Description: The recent explosion of information in innate immune pathways for recognition, effect or responses, and genetic regulation has given impetus to investigations into analogous pathways in the human immune response, which in turn has produced attendant insights into both normal physiology and immunopathology...read more

Product Description: This volume provides a comprehensive and multi-disciplinary overview of the aging lung, written by the main researchers in the field. Current physiological, cellular and molecular understanding of how the lungs age and the relationship to age-associated lung diseases will be presented...read more

Product Description: Malaria is one of the most important "emerging" or "resurgent" infectious diseases. According to the World Health Organization, this mosquito-borne infection is a leading cause of suffering, death, poverty, and underdevelopment in the world today...read more

Product Description: The role of the cytokine, macrophage migration inhibitory factor (MIF), in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well established. The aim of this handbook is to provide an authoritative volume covering all aspects of MIF, from basic molecular biology to structure-function relationships, pathophysiology, genetics, and drug development...read more

Product Description: This volume provides a comprehensive and multidisciplinary overview of fibrocytes, written by the main researchers in the field. It is aimed at a broad audience of scientists and clinicians with an interest in the role of circulating fibrocytes in the etiopathogenesis of different fibrosing disorders, atherosclerosis, autoimmunity, and cancer...read more

Product Description: In recent years, researchers have identified a pivotal, upstream role for macrophage migration inhibitory factor (MIF) in the innate immune response. This pioneering book describes this renaissance of knowledge in the biology of MIF...read more

Product Description: Since the discovery of the circulating fibrocyte in 1994 as a collagen-producing cell of the peripheral blood, the physiologic and pathologic role of this unique cell populaton has grown steadily. This pioneering new book provides the first comprehensive review of the role of fibrocytes in wound repair, granuloma formation, antigen presentation, scar formation, and various fibrosing disorders such as interstitial lung disease and nephrogenic systemic fibrosis...read more