In the twenty-first century, the Apaches join forces with renegade politician Ross Prager, dynamic head of the Posterity Party, and the Chutzba family to battle government injustice

Epithelial phenotype is a dynamic stage of differentiation that can be modulated during several physiological or pathological events. The rapid conversion to a mesenchymal-like phenotype is called an epithelial-mesenchymal transition (EMT). The Rise and Fall of Epithelial Phenotype is the first book to comprehensively introduce the concept of EMT. The first part of this volume describes main examples and models and explains their physiological relevance. These examples include hydra morphogenesis, gastrulation in mouse, drosophila and sea urchin, as well as neural crest cell migration and heart morphogenesis in vertebrates. Part two reviews in detail, specific EMT molecular pathways covering extracellular induction, transduction and transcription response and modulation of cell-cell adhesion structures. It emphasizes new specific pathways with potential medical applications. EMTs can also be linked to pathological events such as wound healing and cancer progression, as detailed in this section of the book.

Great for grades 2-3! Each book in this terrific new series is packed with teacher-tested ideas and activities that teach important reading, writing, grammar, spelling, or listening skills and correlate with the Language Arts Standards. Includes tips for working with second language learners; assessment ideas; and writing, art, music, and movement connections for kids of all learning styles. You’ll also find reproducible graphs, charts, graphic organizers, games, mini-books, easy-to-make manipulatives, and much more! For use with Grades 2-3.