The first HMG-CoA reductase inhibitor (statin) lovastatin, has been on the market since 1987. In that time, five more drugs from this class, atorvastatin, pravastatin, fluvastatin, rosuvastatin, and simvastatin, have been approved by the FDA. Statins, among the top ten most commonly prescribed drugs in the US, are now recommended as first-time treatments by all major regulatory agencies in the US and elsewhere. As shown in numerous clinical trials, statins are extremely powerful and effective in reducing LDL cholesterol, accompanied by a significant reduction of cardiac events and strokes. As a class, they are well-tolerated by most patients and are easy to administer. However, the withdrawal of cerivastatin (Baycol) from the market in 2001 due to severe myopathy in some patients has led to increased concern among clinicians with respect to this and other side effects, such as liver and kidney disease. Some studies suggest this has led to increased reluctance among clinicians to initiate a statin drug regimen or to adjust dosage to increase therapeutic effect. While a small minority of patients do develop serious complications while on statin therapy, current clinical evidence strongly suggests that the benefits of timely statin administration significantly outweigh the risks. Oxford American Pocket Notes: Statin Prescribing Guide aims to provide clinicians with concise, easily accessible guidance on prescribing statins in various clinical settings. This volume features evidence-based discussion on the indications, pharmacokinetics, and safety profiles of the available statins and how these properties translate into selection of the appropriate treatment regimen for the individual patient. Useful tools, such as treatment algorithms, charts, tables, and illustrations greatly help enhance the value of this volume as a portable reference tool.

Product Description: An MCQ book for medical students, related to Kumar and Clark: Clinical Medicine, but able to be used for general revision by all students, whether or not they are using Kumar and Clark as their main text.over 1000 self-assessment questions with answers 3 different types of questions: MCQs, 'best of 5' and short answer questions all 3 types are similar to those used in medical schools throughout clinical years and afterwards for other exams content of questions derived from Kumar and Clark's Clinical Medicine answers derived from Kumar and Clark questions grouped in chapters that reflect the contents list of Kumar and Clark cover will be tied into new 5th edition of Kumar and Clarktypes of questions have been diversified for this edition - no longer just MCQs there are now 3 question types: MCQs, 'best of 5', and short answer questions this will give the book wider appeal - more in keeping with the way exams are going answers will appear at end of chapter - more convenient; readers' requested it answers will include explanations - more helpful; again, responding to readers' request...read more

Product Description: Multiple choice questions (MCQs) are popular with examining bodies because they allow accurate ranking of examinees in a convenient manner. This volume contains over 1600 questions, each with five statements, derived for the fourth edition of Kumar and Clark's "Clinical Medicine"...read more

Product Description: A practical self-assessment text designed to test the examination candidates' underlying knowledge of clinical medicine and diagnostic skills. The presentation of the clinical cases is designed to mirror precisely the examination situation and the cases included are those which most frequently occur...read more