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: Simulation and Decision Making, Multi-Agent Applications, Management and e-Business, Mobile Agents and Robots, and Machine Learning. In addition to the main tracks of the symposium there were the following five special sessions: Agent- Based Optimization (ABO2010), Agent-Enabled Social Computing (AESC2010), Digital Economy (DE2010), Using Intelligent Systems for Information Technology Assessment (ISITA2010) and a Doctoral Track. Accepted and presented papers highlight new trends and challenges in agent and multi-agent research. We hope these results will be of value to the research com- nity working in the fields of artificial intelligence, collective computational intel- gence, robotics, machine learning and, in particular, agent and multi-agent systems technologies and applications. We would like to express our sincere thanks to the Honorary Chairs, Romuald Cwilewicz, President of the Gdynia Maritime University, Poland, and Lakhmi C. Jain, University of South Australia, Australia, for their support. Our special thanks go to the Local Organizing Committee chaired by Ireneusz Czarnowski, who did very solid and excellent work. Thanks are due to the Program Co-chairs, all Program and Reviewer Committee members and all the additional - viewers for their valuable efforts in the review process, which helped us to guarantee the highest quality of selected papers for the conference. We cordially thank the - ganizers and chairs of special sessions, which essentially contributed to the success of the conference.